Val-Val-Gly

• 分子结构分类: 有机化合物 - 有机酸及其衍生物 - 羧酸及其衍生物
• 英文名称: Val-Val-Gly
• 英文别名: 2-[[(2S)-2-[[(2S)-2-amino-3-methylbutanoyl]amino]-3-methylbutanoyl]amino]acetic acid
• 化学式: C₁₂H₂₃N₃O₄
• 分子量: 273.33
• InChiKey: AEFJNECXZCODJM-UWVGGRQHSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  -3
• 重原子数：
  19
• 可旋转键数：
  7
• 环数：
  0.0
• sp3杂化的碳原子比例：
  0.75
• 拓扑面积：
  122
• 氢给体数：
  4
• 氢受体数：
  5

文献信息

• METHOD FOR PRODUCING GAMMA -GLUTAMYL-VALYL-GLYCINE CRYSTAL
  申请人：AJINOMOTO CO., INC.

  公开号：US20150361133A1

  公开（公告）日：2015-12-17

  The present invention provides a method for efficiently producing a γ-glutamyl-valyl-glycine crystal. Specifically, the present invention provides a method for producing a γ-glutamyl-valyl-glycine crystal, which includes the steps of: preparing a mixed solution of valyl-glycine or a salt thereof and γ-glutamyl-valyl-glycine, wherein the mixed solution contains valyl-glycine or the salt thereof in an amount of 20 mass % or more relative to the mass of γ-glutamyl-valyl-glycine; adjusting the amount of valyl-glycine or the salt thereof in the prepared mixed solution to 0.1 mass % or more and less than 20 mass % relative to the mass of γ-glutamyl-valyl-glycine to prepare a γ-glutamyl-valyl-glycine solution; and subjecting the γ-glutamyl-valyl-glycine solution to a crystallization procedure to produce the γ-glutamyl-valyl-glycine crystal.

  本发明提供了一种高效生产γ-谷氨酰-缬氨酸-甘氨酸晶体的方法。具体来说，本发明提供了一种生产γ-谷氨酰-缬氨酸-甘氨酸晶体的方法，包括以下步骤：制备缬氨酸-甘氨酸或其盐和γ-谷氨酰-缬氨酸的混合溶液，其中混合溶液中缬氨酸或其盐的质量占γ-谷氨酰-缬氨酸质量的20%或以上；调整制备的混合溶液中缬氨酸或其盐的量，使其相对于γ-谷氨酰-缬氨酸的质量为0.1%或以上但小于20%；将γ-谷氨酰-缬氨酸溶液经过结晶程序进行结晶，生产γ-谷氨酰-缬氨酸晶体。
• METHOD FOR PRODUCING -GLUTAMYL-VALYL-GLYCINE CRYSTAL
  申请人：Ajinomoto Co., Inc.

  公开号：EP2883960A1

  公开（公告）日：2015-06-17

  The present invention provides a method for efficiently producing a γ-glutamyl-valyl-glycine crystal. Specifically, the present invention provides a method for producing a γ-glutamyl-valyl-glycine crystal, which includes the steps of: preparing a mixed solution of valyl-glycine or a salt thereof and γ-glutamyl-valyl-glycine, wherein the mixed solution contains valyl-glycine or the salt thereof in an amount of 20 mass% or more relative to the mass of γ-glutamyl-valyl-glycine; adjusting the amount of valyl-glycine or the salt thereof in the prepared mixed solution to 0.1 mass% or more and less than 20 mass% relative to the mass of γ-glutamyl-valyl-glycine to prepare a γ-glutamyl-valyl-glycine solution; and subjecting the γ-glutamyl-valyl-glycine solution to a crystallization procedure to produce the γ-glutamyl-valyl-glycine crystal.

  本发明提供了一种高效生产γ-谷氨酰-缬氨酰-甘氨酸晶体的方法。具体来说，本发明提供了一种生产γ-谷氨酰-缬氨酰-甘氨酸晶体的方法，该方法包括以下步骤：制备缬氨酰-甘氨酸或其盐和γ-谷氨酰-缬氨酰-甘氨酸的混合溶液，其中混合溶液中缬氨酰-甘氨酸或其盐的含量相对于γ-谷氨酰-缬氨酰-甘氨酸的质量大于等于 20 质量％；将制备的混合溶液中缬氨酰-甘氨酸或其盐的含量调整为 0.1 质量％或更多，但相对于 γ-谷氨酰-缬氨酰-甘氨酸的质量小于 20 质量％，以制备 γ-谷氨酰-缬氨酰-甘氨酸溶液；并将 γ-谷氨酰-缬氨酰-甘氨酸溶液进行结晶处理，以生成 γ-谷氨酰-缬氨酰-甘氨酸晶体。
• METHOD FOR PRODUCING gamma-GLUTAMYL-VALYL-GLYCINE CRYSTAL
  申请人：Ajinomoto Co., Inc.

  公开号：EP2883960B1

  公开（公告）日：2020-05-13
• US9512177B2
  申请人：——

  公开号：US9512177B2

  公开（公告）日：2016-12-06