Isoleucyl-Glutamine

• 分子结构分类: 有机化合物 - 有机酸及其衍生物 - 羧酸及其衍生物
• 英文名称: Isoleucyl-Glutamine
• 英文别名: (2S)-5-amino-2-[[(2S,3S)-2-amino-3-methylpentanoyl]amino]-5-oxopentanoic acid
• 化学式: C₁₁H₂₁N₃O₄
• mdl: MFCD00238001
• 分子量: 259.3
• InChiKey: CNPNWGHRMBQHBZ-ZKWXMUAHSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  -4.2
• 重原子数：
  18
• 可旋转键数：
  8
• 环数：
  0.0
• sp3杂化的碳原子比例：
  0.727
• 拓扑面积：
  136
• 氢给体数：
  4
• 氢受体数：
  5

文献信息

• Compositions to improve tic disorders
  申请人：Ozeki Makoto

  公开号：US20060217321A1

  公开（公告）日：2006-09-28

  Tic disorders can be improved by administering theanine, an amino acid that crosses the blood-brain barrier, or a dipeptide consisting of theanine and a different amino acid. In addition, these compositions can be added to foods and drinks or pharmaceuticals.

  滴状障碍可以通过给予茶氨酸改善，这是一种可以穿过血脑屏障的氨基酸，或者是由茶氨酸和另一种氨基酸组成的二肽。此外，这些组合物可以添加到食品和饮料或药品中。
• Peptide-forming enzyme gene, peptide-forming enzyme, and peptide producing method
  申请人：Tonouchi Naoto

  公开号：US20050037453A1

  公开（公告）日：2005-02-17

  The present invention provides a method for producing dipeptide using inexpensively acquirable starting materials by an industrially advantageous and simple pathway. Dipeptide is produced from L-amino acid ester and L-amino acid using a culture of microbes having the ability to produce a dipeptide from an L-amino acid ester and an L-amino acid, using microbial cells isolated from the culture, or a treated microbial cell product of the microbe.

  本发明提供了一种使用成本低廉的起始材料通过工业上有利且简单的途径生产二肽的方法。通过使用具有从L-氨基酸酯和L-氨基酸生产二肽的能力的微生物培养物，使用从培养物中分离出的微生物细胞或经处理的微生物细胞产物，从L-氨基酸酯和L-氨基酸生产二肽。
• Peptide-forming enzyme gene, peptide-forming enzyme, and dipeptide producing method
  申请人：Ajinomoto Co., Inc.

  公开号：EP1911839A1

  公开（公告）日：2008-04-16

  The present invention provides a method for producing dipeptide using inexpensively acquirable starting materials by an industrially advantageous and simple pathway. Dipeptide is produced from L-amino acid ester and L-amino acid using a culture of microbes having the ability to produce a dipeptide from an L-amino acid ester and an L-amino acid, using microbial cells isolated from the culture, or a treated microbial cell product of the microbe.

  本发明提供了一种利用廉价的可获得的起始原料，通过工业上有利的简单途径生产二肽的方法。二肽是利用具有从 L-氨基酸酯和 L-氨基酸中生产二肽能力的微生物培养物，使用从培养物中分离的微生物细胞或经处理的微生物细胞产物，从 L-氨基酸酯和 L-氨基酸中生产出来的。
• Glutamine or glutamine-containing dipeptide in a specific dosage for the treatment of inflammation
  申请人：Biotempt B.V.

  公开号：EP2106791A1

  公开（公告）日：2009-10-07

  Described are methods of treating or preventing an inflammation by administering to a patient in need thereof a pharmacologic dose of glutamine or a glutamine-containing dipeptide in a pharmaceutically acceptable carrier, wherein said dose is selected from a range of 0.09 to 90mg glutamine per kg bodyweight of the patient.

  描述了治疗或预防炎症的方法，给有需要的患者施用药理剂量的谷氨酰胺或含谷氨酰胺二肽的药学上可接受的载体，其中所述剂量选自患者每公斤体重 0.09 至 90 毫克谷氨酰胺的范围。
• COMPOSITION FOR EMBRYO CULTURE
  申请人：Fuso Pharmaceutical Industries, Ltd.

  公开号：EP2740790A1

  公开（公告）日：2014-06-11

  Provided is a composition for embryo culture, which contains a constitution suitable for embryo culture. Provided is a composition for embryo culture, which contains (a) a constitution shown in Table A below.

  本发明提供了一种胚胎培养用组合物，它含有适合胚胎培养的成分。本发明提供了一种用于胚胎培养的组合物，它含有 (a) 下表 A 所示的成分。