(2S)-2-(3-methylpyrazol-1-yl)propanoic acid

• 分子结构分类: 有机化合物 - 有机酸及其衍生物 - 羧酸及其衍生物
• 英文名称: (2S)-2-(3-methylpyrazol-1-yl)propanoic acid
• 化学式: C₇H₁₀N₂O₂
• mdl: MFCD03419630
• 分子量: 154.17
• InChiKey: DITJIAJNAOGEPM-LURJTMIESA-N

计算性质

• 辛醇/水分配系数(LogP)：
  0.7
• 重原子数：
  11
• 可旋转键数：
  2
• 环数：
  1.0
• sp3杂化的碳原子比例：
  0.43
• 拓扑面积：
  55.1
• 氢给体数：
  1
• 氢受体数：
  3

文献信息

• PROCESS FOR MAKING BETA 3 AGONISTS AND INTERMEDIATES
  申请人：MERCK SHARP & DOHME, CORP.

  公开号：US20150087832A1

  公开（公告）日：2015-03-26

  The present invention is directed to processes for preparing beta 3 agonists of Formula (I) and Formula (II) and their intermediates. The beta 3 agonists are useful in the treatment of certain disorders, including overactive bladder, urinary incontinence, and urinary urgency.
• Process for Making Beta 3 Agonists and Intermediates
  申请人：Merck Sharp & Dohme Corp.

  公开号：US20160176884A1

  公开（公告）日：2016-06-23

  The present invention is directed to processes for preparing beta 3 agonists of Formula (I) and Formula (II) and their intermediates. The beta 3 agonists are useful in the treatment of certain disorders, including overactive bladder, urinary incontinence, and urinary urgency.
• US9822121B2
  申请人：——

  公开号：US9822121B2

  公开（公告）日：2017-11-21