5-{4-[(3-Chlorophenyl)methoxy]phenylmethylene}-2,4-thiazolidinedione

• 分子结构分类: 有机化合物 - 苯类化合物 - 苯酚醚
• 英文名称: 5-{4-[(3-Chlorophenyl)methoxy]phenylmethylene}-2,4-thiazolidinedione
• 英文别名: (5E)-5-{4-[(3-chlorobenzyl)oxy]benzylidene}-1,3-thiazolidine-2,4-dione；(5E)-5-({4-[(3-chlorophenyl)methoxy]phenyl}methylidene)-1,3-thiazolidine-2,4-dione；(5E)-5-[[4-[(3-chlorophenyl)methoxy]phenyl]methylidene]-1,3-thiazolidine-2,4-dione
• 化学式: C₁₇H₁₂ClNO₃S
• 分子量: 345.806
• InChiKey: WKGUDPFFWIPJFG-OQLLNIDSSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  4.3
• 重原子数：
  23
• 可旋转键数：
  4
• 环数：
  3.0
• sp3杂化的碳原子比例：
  0.06
• 拓扑面积：
  80.7
• 氢给体数：
  1
• 氢受体数：
  4

文献信息

• Benzylidene-1,3-thiazolidine-2,4-dione compounds for promoting and/or inducing and/or stimulating the pigmentation of keratin materials and/or for limiting their depigmentation and/or whitening
  申请人：Boulle Christophe

  公开号：US20070071699A1

  公开（公告）日：2007-03-29

  The benzylidene-1,3-thiazolidine-2,4-dione compounds having the structural formula (I), or salt and/or solvate and/or isomer thereof: are useful active agents for promoting and/or inducing and/or stimulating the pigmentation of keratin materials and/or preventing and/or limiting the depigmentation and/or bleaching thereof, particularly of human head hair, beard hair, moustache hair, eyelashes and eyebrows, and advantageously are active agents for preventing and/or limiting the canities of human keratin fibers.

  具有结构式（I）或其盐和/或溶剂和/或异构体的苯甲醛基-1,3-噻唑啉-2,4-二酮化合物是促进和/或诱导和/或刺激角蛋白质材料的色素沉淀和/或预防和/或限制其褪色和漂白的有用活性剂，特别是人类头发、胡须、胡子、睫毛和眉毛，优点是预防和/或限制人类角蛋白质纤维的白发。
• US5326770A
  申请人：——

  公开号：US5326770A

  公开（公告）日：1994-07-05