三(2,4-二甲基苯基)亚磷酸酯 | 33073-05-1

• 分子结构分类: 有机化合物 - 苯类化合物 - 苯和取代衍生物
• 中文名称: 三(2,4-二甲基苯基)亚磷酸酯
• 英文名称: Tris(2.4-dimethylphenyl)phosphit
• 英文别名: tri-(2,4-dimethylphenyl)phosphite；Tris(2,4-dimethylphenyl) phosphite
• CAS: 33073-05-1
• 化学式: C₂₄H₂₇O₃P
• 分子量: 394.45
• InChiKey: HABWCPIKWOZMSN-UHFFFAOYSA-N

物化性质

• 沸点：
  459.3±45.0 °C(Predicted)

计算性质

• 辛醇/水分配系数(LogP)：
  7.7
• 重原子数：
  28
• 可旋转键数：
  6
• 环数：
  3.0
• sp3杂化的碳原子比例：
  0.25
• 拓扑面积：
  27.7
• 氢给体数：
  0
• 氢受体数：
  3

反应信息

• 作为反应物：
  描述：

  三(2,4-二甲基苯基)亚磷酸酯 在 tris-(dibenzylideneacetone)dipalladium(0) 、 苯基三氟甲烷磺酸酯 作用下， 以 neat (no solvent) 为溶剂， 反应 16.0h， 以87%的产率得到bis(2,4-dimethylphenyl) (2,4-dimethylphenyl)phosphonate
  参考文献：
  名称：

  通过Michaelis–Arbuzov重排由（ArO）3 P从钯催化无溶剂制备芳基膦酸酯ArP（O）（OAr）2

  摘要：

  本发明公开了钯催化的三芳基亚磷酸酯的Michaelis-Arbuzov重排以产生相应的芳基膦酸酯，产率高至优异。与传统方法相比，此新方法具有很高的原子效率，并且很通用，因为它可以轻松扩展到芳基亚膦酸酯和次膦酸酯。还证实了在低催化剂用量的情况下（PhO）3 P对PhP（O）（OPh）2的克级反应，显示了其潜在的实用价值。提出了一种合理的机制。

  DOI：

  10.1021/acs.organomet.0c00573
• 作为产物：
  描述：

  2,4-二甲基苯酚 在 三氯化磷 作用下， 生成 三(2,4-二甲基苯基)亚磷酸酯
  参考文献：
  名称：

  Formation of three-coordinate nickel(0) complexes by phosphorus ligand dissociation from NiL4

  摘要：

  DOI：

  10.1021/ja00808a009

文献信息

• HYDROCYANATION PROCESS WITH REDUCED YIELD LOSSES
  申请人：FOO THOMAS

  公开号：US20080015381A1

  公开（公告）日：2008-01-17

  The invention provides a hydrocyanation process for the production of adiponitrile and other dinitriles having six carbon atoms, the process comprising: a) forming a reaction mixture in the presence of at least one Lewis acid, said reaction mixture comprising ethylenically unsaturated nitrites having five carbon atoms, hydrogen cyanide, and a catalyst precursor composition, by continuously feeding ethylenically unsaturated nitrites, hydrogen cyanide, and a catalyst precursor composition; b) controlling X and Z, wherein X is the overall feed molar ratio of 2-pentenenitriles to all unsaturated nitriles and Z is the overall feed molar ratio of hydrogen cyanide to all unsaturated nitrites, by selecting a value for X in the range from about 0.001 to about 0.5, and a value for Z in the range from about 0.5/1 to about 0.99/1, such that the value of quotient Q, wherein Q = X [ ( moles   3  PN + 4  PN   in   the   feed ) ( moles   all   unsaturated   nitriles   in   the   feed ) ] - Z is in the range from about 0.2 to about 10, wherein 3PN is 3-pentenenitriles and 4PN is 4-pentenenitrile; and c) withdrawing a reaction product mixture comprising adiponitrile; wherein the ratio of the concentration of 2-pentenenitriles to the concentration of 3-pentenenitriles in the reaction mixture is from about 0.2/1 to about 10/1; wherein the catalyst precursor composition comprises a zero-valent nickel and at least one bidentate phosphite ligand; and wherein the bidentate phosphite ligand is selected from a member of the group represented by Formulas I and 11 as described herein.

  该发明提供了一种水氰化过程，用于生产己二腈和其他具有六个碳原子的二腈，该过程包括： a) 在至少一种Lewis酸的存在下形成反应混合物，所述反应混合物包括具有五个碳原子的乙烯基未饱和亚硝酸酯，氰化氢和催化剂前体组成物，通过持续进料乙烯基未饱和亚硝酸酯，氰化氢和催化剂前体组成物； b) 控制X和Z，其中X是2-戊烯亚硝酸酯对所有未饱和亚硝酸酯的总进料摩尔比，Z是氰化氢对所有未饱和亚硝酸酯的总进料摩尔比，通过选择X值在约0.001至约0.5范围内的值，Z值在约0.5/1至约0.99/1范围内的值，使商数Q的值在约0.2至约10范围内，其中Q=X[(进料中的摩尔数3PN+4PN)(进料中的所有未饱和亚硝酸酯的摩尔数)]-Z； c) 撤回包括己二腈的反应产物混合物； 其中反应混合物中2-戊烯亚硝酸酯与3-戊烯亚硝酸酯的浓度比在约0.2/1至约10/1之间； 其中催化剂前体组成物包括零价镍和至少一种双齿膦酸酯配体； 双齿膦酸酯配体从以下描述的I和11式所代表的组中选择。
• HYDROCYANATION OF PENTENENITRILES
  申请人：Foo Thomas

  公开号：US20090182164A1

  公开（公告）日：2009-07-16

  The invention provides a hydrocyanation process to produce adiponitrile and other dinitriles having six carbon atoms, in the presence of catalyst composition comprising a zero-valent nickel and at least one bidentate phosphorus-containing ligand wherein the bidentate phosphorus-containing ligand gives acceptable results according to at least one protocol of the 2-Pentenenitrile Hydrocyanation Test Method.

  本发明提供了一种氢氰化工艺，用于在包含零价镍和至少一种双齿含磷配体的催化剂组合物存在下生产己二腈和其他具有六个碳原子的二腈，其中所述双齿含磷配体根据至少一种2-戊烯腈氢氰化测试方法的规程给出可接受的结果。
• Process for Production of Trialkylphosphine
  申请人：Ide Toshihisa

  公开号：US20120220803A1

  公开（公告）日：2012-08-30

  A production process of a trialkylphosphine according to the present invention includes: a first step of forming a trialkylphosphine by reaction of an organic metal compound and an organic phosphorous compound in an ether solvent having a difference in boiling point with the trialkylphosphine formed such that the difference in boiling point is in a range of 0° C. to 20° C.; a second step of obtaining a silver complex by absorption of a gas phase of the first step into an aqueous solution of AgI and KI; a third step of heating the silver complex obtained in the second step, in a metallic reaction vessel, at a temperature of 170° C. to 350° C. in a reduced pressure atmosphere of 1.333×10 −7 MPa to 6.133×10 −2 MPa; and a fourth step of cooling a gas product of the third step at a very low temperature range of −196° C. to −50° C. to trap the trialkylphosphine.

  根据本发明的一种三烷基膦的生产工艺包括：第一步是通过有机金属化合物和有机磷化合物在具有与形成的三烷基膦具有沸点差的醚溶剂中反应形成三烷基膦，使沸点差在0°C至20°C范围内；第二步是通过将第一步的气相吸收到AgI和KI的水溶液中获得银络合物；第三步是在金属反应容器中，将第二步获得的银络合物在170°C至350°C的温度下，在1.333×10^-7MPa至6.133×10^-2MPa的减压气氛中加热；第四步是在非常低的温度范围内（-196°C至-50°C）冷却第三步的气体产物以捕获三烷基膦。
• Selective Hydrogenation Catalyst and Methods of Making and Using Same
  申请人：Cheung Tin-Tack Peter

  公开号：US20100228065A1

  公开（公告）日：2010-09-09

  A composition comprising a supported hydrogenation catalyst comprising palladium and an organophosphorous compound, the supported hydrogenation catalyst being capable of selectively hydrogenating highly unsaturated hydrocarbons to unsaturated hydrocarbons. A method of making a selective hydrogenation catalyst comprising contacting a support with a palladium-containing compound to form a palladium supported composition, contacting the palladium supported composition with an organophosphorus compound to form a catalyst precursor, and reducing the catalyst precursor to form the catalyst. A method of selectively hydrogenating highly unsaturated hydrocarbons to an unsaturated hydrocarbon enriched composition comprising contacting a supported catalyst comprising palladium and an organophosphorous compound with a feed comprising highly unsaturated hydrocarbon under conditions suitable for hydrogenating at least a portion of the highly unsaturated hydrocarbon feed to form the unsaturated hydrocarbon enriched composition.

  一种包括支持的氢化催化剂的组合物，其中氢化催化剂包括钯和有机磷化合物，支持的氢化催化剂能够选择性地将高度不饱和烃氢化为不饱和烃。一种制备选择性氢化催化剂的方法，包括将支持物与含钯化合物接触以形成支持的钯组合物，将支持的钯组合物与有机磷化合物接触以形成催化剂前体，并还原催化剂前体以形成催化剂。一种将高度不饱和烃选择性氢化为富含不饱和烃的组合物的方法，包括将包括钯和有机磷化合物的支持催化剂与含高度不饱和烃的进料接触，在适宜的氢化条件下至少部分氢化高度不饱和烃进料以形成富含不饱和烃的组合物。
• Method for the purification of triorganophosphites by treatment with a basic additive
  申请人：Ritter Joachim C.

  公开号：US20070219386A1

  公开（公告）日：2007-09-20

  The invention provides a method for separating one or more triorganophosphite components from a crude phosphite mixture containing acidic hydrolysis products, the method comprising: contacting said crude phosphite mixture with a basic additive to produce a second mixture comprising a first phase and a second phase, wherein said first phase comprises the basic additive and one or more components independently selected from the group consisting of (R 2 O)(R 3 O)POH, (R 1 O)(HO)PO(H) and H 3 PO 3 , wherein R 1 , R 2 and R 3 are independently selected from the group consisting of C 1 to C 18 alkyl, C 6 to C 18 aryl and hydroxyaryl, and C 3 to C 18 cycloalkyl and hydroxyalkyl radicals, and wherein R 2 and R 3 can optionally be connected to each other directly by a chemical bond or through an intermediate divalent group R 9 ; and said second phase comprises one or more triorganophosphite components independently selected from the group consisting of (R 4 O)(R 5 O)P(OR 6 ) and ((R 7 O)(R 8 O)PO) n A, wherein R 4 , R 5 , R 6 , R 7 and R 8 are independently selected from the group consisting of C 1 to C 18 alkyl, C 6 to C 18 aryl and C 3 to C 18 cycloalkyl radicals, wherein each of R 4 , R 5 and R 6 can optionally be connected to one or both of the other two directly by a chemical bond or through an intermediate divalent group R 10 , wherein R 7 and R 8 can optionally be connected to each other directly by a chemical bond or through an intermediate divalent group R 11 , wherein A is an optionally substituted or unsubstituted aliphatic, aromatic or heteroaromatic radical, and wherein n is an integer greater than 1; and R 9 , R 10 , and R 11 are independently selected from the group consisting of —O—, —S—, and —CH(R 12 )—, wherein R 12 is selected from the group consisting of H, C 6 to C 18 aryl, and C 1 to C 18 alkyl.

  本发明提供了一种从含有酸性水解产物的粗磷酸酯混合物中分离一个或多个三元膦酯组分的方法，包括：将所述粗磷酸酯混合物与碱性添加剂接触以产生包含第一相和第二相的第二混合物，其中所述第一相包括碱性添加剂和独立选择自羟基芳基、C1至C18烷基、C6至C18芳基和羟基芳基、C3至C18环烷基和羟基烷基基团的一个或多个组分，其中所述第二相包括独立选择自C1至C18烷基、C6至C18芳基和C3至C18环烷基基团的一个或多个三元膦酯组分，其中R4、R5、R6、R7和R8独立选择自C1至C18烷基、C6至C18芳基和C3至C18环烷基基团，其中R4、R5和R6中的每一个可选择通过化学键或通过中间的二价基团R10直接连接到其它两个中的一个或两个，其中R7和R8可选择通过化学键或通过中间的二价基团R11直接连接到彼此，其中A是一个可选择被取代或未取代的脂肪族、芳香族或杂环芳香族基团，n是大于1的整数；R9、R10和R11独立选择自—O—、—S—和—CH(R12)—基团，其中R12选择自H、C6至C18芳基和C1至C18烷基。