(+/-)-6-allyl-1-[3-(4-methoxybenzyloxy)propyl]-5,6-dimethylcyclohexen-1-ene

• 分子结构分类: 有机化合物 - 苯类化合物 - 苯和取代衍生物
• 英文名称: (+/-)-6-allyl-1-[3-(4-methoxybenzyloxy)propyl]-5,6-dimethylcyclohexen-1-ene
• 英文别名: 1-[3-[(5S,6R)-5,6-dimethyl-6-prop-2-enylcyclohexen-1-yl]propoxymethyl]-4-methoxybenzene
• 化学式: C₂₂H₃₂O₂
• 分子量: 328.495
• InChiKey: ADCYNEBWWPSLDY-PGRDOPGGSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  5.6
• 重原子数：
  24
• 可旋转键数：
  9
• 环数：
  2.0
• sp3杂化的碳原子比例：
  0.55
• 拓扑面积：
  18.5
• 氢给体数：
  0
• 氢受体数：
  2

反应信息

• 作为产物：
  描述：

  3-[(4-甲氧基苄基)氧基]-1-丙醇 在 4-二甲氨基吡啶 、 叔丁基锂 、 sodium iodide 作用下， 以 乙醚 、 二氯甲烷 、 丙酮 为溶剂， 反应 33.0h， 生成 (+/-)-6-allyl-1-[3-(4-methoxybenzyloxy)propyl]-5,6-dimethylcyclohexen-1-ene
  参考文献：
  名称：

  Studies on the synthesis of (±)-pathylactone A, a nor-sesquiterpene lactone isolated from marine sources

  摘要：

  An approach to the synthesis of a highly substituted carbon skeleton exhibited by some unusual nor-sesquiterpenes isolated from marine sources, is described. Our strategy was applied for the total synthesis of pathylactone A, which has now been prepared by an unambiguous route and found to be different from the natural product. (C) 2002 Elsevier Science Ltd. All rights reserved.

  DOI：

  10.1016/s0040-4020(02)00058-3

文献信息

• Studies on the synthesis of (±)-pathylactone A, a nor-sesquiterpene lactone isolated from marine sources
  作者：Fernando Coelho、Gaspar Diaz

  DOI：10.1016/s0040-4020(02)00058-3

  日期：2002.2

  An approach to the synthesis of a highly substituted carbon skeleton exhibited by some unusual nor-sesquiterpenes isolated from marine sources, is described. Our strategy was applied for the total synthesis of pathylactone A, which has now been prepared by an unambiguous route and found to be different from the natural product. (C) 2002 Elsevier Science Ltd. All rights reserved.