(3R)-3-amino-3-(5-methyl-3-oxo-1,2-oxazol-4-yl)propanoic acid

• 分子结构分类: 有机化合物 - 有机酸及其衍生物 - 羧酸及其衍生物
• 英文名称: (3R)-3-amino-3-(5-methyl-3-oxo-1,2-oxazol-4-yl)propanoic acid
• 化学式: C₇H₁₀N₂O₄
• 分子量: 186.17
• InChiKey: VYDDCJKXVNKSGD-SCSAIBSYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  -2.6
• 重原子数：
  13
• 可旋转键数：
  2
• 环数：
  1.0
• sp3杂化的碳原子比例：
  0.43
• 拓扑面积：
  106
• 氢给体数：
  2
• 氢受体数：
  4

文献信息

• RADIOLABELED MICROTUBULE IMAGING COMPOUNDS AND USES THEREOF
  申请人：The Trustees of Columbia University in the City of New York

  公开号：US20200290976A1

  公开（公告）日：2020-09-17

  The present disclosure relates to radiolabeled compounds and methods of uses for diagnosis, monitoring, and treatment of various degenerative neurological disorders, neuropsychiatric disorders, brain injuries, vascular diseases, and cancers. Radiolabled compounds for imaging of microtubules or microtubules and other targets using positron-emission tomography (PET) are specifically disclosed.