tridec-12-en-1-yl acrylate

• 分子结构分类: 有机化合物 - 脂质和类脂质分子 - 脂肪酰基
• 英文名称: tridec-12-en-1-yl acrylate
• 英文别名: Tridec-12-enyl prop-2-enoate；tridec-12-enyl prop-2-enoate
• 化学式: C₁₆H₂₈O₂
• 分子量: 252.397
• InChiKey: AOJVOWGMVKOPBC-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  6.3
• 重原子数：
  18
• 可旋转键数：
  14
• 环数：
  0.0
• sp3杂化的碳原子比例：
  0.69
• 拓扑面积：
  26.3
• 氢给体数：
  0
• 氢受体数：
  2

反应信息

• 作为反应物：
  描述：

  tridec-12-en-1-yl acrylate 在 Mo(NC₆F₅)(CHCMe₂Ph)(2,5-dimethylpyrrolide)(2,6-dimesitylphenoxide) 作用下， 以 苯 为溶剂， 反应 2.0h， 以44%的产率得到(Z)-oxacyclopentadec-3-en-2-one
  参考文献：
  名称：

  通过催化立体选择性闭环复分解制备大环Z-烯酸酯和(E,Z)-或(Z,E)-二烯酸酯

  摘要：

  公开了产生Z-烯酸酯以及(E,Z)-或(Z,E)-二烯酸酯的催化剂控制的立体选择性大环闭环复分解反应的第一个实例。3.0-10 mol% 的 Mo 基单芳氧基吡咯化合物配合物促进的反应在室温下 2-6 小时内完成。所需的大环以 79:21 至 >98:2 Z/E 选择性形成；层析后可获得立体异构纯产物，产率为 43-75%。通过天然产物 (+)-阿西西林的简明形式合成的应用证明了实用性。

  DOI：

  10.1021/ja510768c
• 作为产物：
  描述：

  十三碳-12-烯-1-醇 、 丙烯酰氯 在 三乙胺 作用下， 以 二氯甲烷 为溶剂， 反应 1.0h， 以83%的产率得到tridec-12-en-1-yl acrylate
  参考文献：
  名称：

  通过催化立体选择性闭环复分解制备大环Z-烯酸酯和(E,Z)-或(Z,E)-二烯酸酯

  摘要：

  公开了产生Z-烯酸酯以及(E,Z)-或(Z,E)-二烯酸酯的催化剂控制的立体选择性大环闭环复分解反应的第一个实例。3.0-10 mol% 的 Mo 基单芳氧基吡咯化合物配合物促进的反应在室温下 2-6 小时内完成。所需的大环以 79:21 至 >98:2 Z/E 选择性形成；层析后可获得立体异构纯产物，产率为 43-75%。通过天然产物 (+)-阿西西林的简明形式合成的应用证明了实用性。

  DOI：

  10.1021/ja510768c

文献信息

• Preparation of Organosilicon Compound Having (Meth)acryloyloxy Group
  申请人：Shin-Etsu Chemical Co., Ltd.

  公开号：US20210139515A1

  公开（公告）日：2021-05-13

  A (meth)acryloyloxy-containing organosilicon compound (3) is prepared by simultaneously feeding a hydrohalosilane compound (1) and a (meth)acrylate compound (2) in the presence of a polymerization inhibitor to a reaction system, and effecting hydrosilylation reaction in the presence of a platinum catalyst. The content of (meth)acrylate compound (2) is 0-100 mol % based on the content of organosilicon compound (3) in the reaction system. R is a C 1 -C 10 monovalent hydrocarbon group, X is halogen, n is 1, 2 or 3, R 2 is H or methyl, and R 3 is a C 1 -C 18 alkylene group.

  通过在聚合抑制剂的存在下同时加入羟卤代硅烷化合物（1）和（甲基）丙烯酸酯化合物（2）到反应体系中，利用铂催化剂进行氢硅烷化反应，制备含有（甲基）丙烯酰氧基的有机硅化合物（3）。在反应体系中，（甲基）丙烯酸酯化合物（2）的含量基于有机硅化合物（3）的含量为0-100摩尔％。其中，R是C1-C10一价烃基，X是卤素，n为1、2或3，R2为氢或甲基，R3为C1-C18烷基。
• PREPARATION OF ORGANOSILICON COMPOUND HAVING (METH)ACRYLOYLOXY GROUP
  申请人：Shin-Etsu Chemical Co., Ltd.

  公开号：EP3819301A1

  公开（公告）日：2021-05-12

  A (meth)acryloyloxy-containing organosilicon compound (3) is prepared by simultaneously feeding a hydrohalosilane compound (1) and a (meth)acrylate compound (2) in the presence of a polymerization inhibitor to a reaction system, and effecting hydrosilylation reaction in the presence of a platinum catalyst. The content of (meth)acrylate compound (2) is 0-100 mol% based on the content of organosilicon compound (3) in the reaction system. R1 is a C1-C10 monovalent hydrocarbon group, X is halogen, n is 1, 2 or 3, R2 is H or methyl, and R3 is a C1-C18 alkylene group.

  在聚合抑制剂存在下，将氢卤硅烷化合物（1）和(甲基)丙烯酸酯化合物（2）同时加入反应体系，并在铂催化剂存在下进行氢化硅反应，制备含(甲基)丙烯酰氧基的有机硅化合物（3）。根据反应体系中有机硅化合物（3）的含量，(甲基)丙烯酸酯化合物（2）的含量为 0-100 摩尔%。R1 是 C1-C10 单价烃基，X 是卤素，n 是 1、2 或 3，R2 是 H 或甲基，R3 是 C1-C18 亚烷基。
• BIO-ELECTRODE COMPOSITION, BIO-ELECTRODE, METHOD FOR MANUFACTURING BIO-ELECTRODE, POLYMER COMPOUND, AND COMPOSITE
  申请人：Shin-Etsu Chemical Co., Ltd.

  公开号：EP3984456A1

  公开（公告）日：2022-04-20

  A bio-electrode composition contains (A) a composite of an ionic polymer material and particles. The component (A) contains the particles bonding to the polymer containing a repeating unit having a structure selected from the group consisting of salts of ammonium, lithium, sodium, potassium, and silver formed with any of fluorosulfonic acid, fluorosulfonimide, and N-carbonyl-fluorosulfonamide. Thus, the present invention provides: a bio-electrode composition capable of forming a living body contact layer for a bio-electrode which is excellent in electric conductivity and biocompatibility, light-weight, and manufacturable at low cost, and which prevents significant reduction in the electric conductivity even when wetted with water or dried; a bio-electrode including a living body contact layer formed of the bio-electrode composition; and a method for manufacturing the bio-electrode.

  一种生物电极组合物包含（A）离子聚合物材料和颗粒的复合材料。组分（A）包含与聚合物粘合的颗粒，聚合物含有重复单元，该重复单元的结构选自由铵盐、锂盐、钠盐、钾盐和银盐组成的组，这些盐与氟磺酸、氟磺酰亚胺和 N-羰基-氟磺酰胺中的任意一种形成。因此，本发明提供了：一种能够为生物电极形成活体接触层的生物电极组合物，其导电性和生物相容性极佳，重量轻，可低成本制造，即使被水浸湿或干燥，也不会显著降低导电性；一种生物电极，包括由该生物电极组合物形成的活体接触层；以及一种制造该生物电极的方法。
• Preparation of organosilicon compound having (meth)acryloyloxy group
  申请人：Shin-Etsu Chemical Co., Ltd.

  公开号：US11377455B2

  公开（公告）日：2022-07-05

  A (meth)acryloyloxy-containing organosilicon compound (3) is prepared by simultaneously feeding a hydrohalosilane compound (1) and a (meth)acrylate compound (2) in the presence of a polymerization inhibitor to a reaction system, and effecting hydrosilylation reaction in the presence of a platinum catalyst. The content of (meth)acrylate compound (2) is 0-100 mol % based on the content of organosilicon compound (3) in the reaction system. R1 is a C1-C10 monovalent hydrocarbon group, X is halogen, n is 1, 2 or 3, R2 is H or methyl, and R3 is a C1-C18 alkylene group.

  含(meth)acryloyloxy基的有机硅化合物(3)，是将含卤有机硅烷化合物(1)与(meth)acrylate化合物(2)同时加入到装有聚合抑制剂的反应体系中，并在铂催化剂存在下进行氢硅化反应而得到了。基于反应体系中有机硅化合物(3)的量，(meth)acrylate化合物(2)的含量为0-100mol%。R1是C1-C10的单价烃基，X是卤素，n为1、2或3，R2是H或甲基，R3是C1-C18的亚烷基。
• BIO-ELECTRODE COMPOSITION, BIO-ELECTRODE, METHOD FOR MANUFACTURING BIO-ELECTRODE, AND REACTION COMPOSITE
  申请人：SHIN-ETSU CHEMICAL CO., LTD.

  公开号：US20220135763A1

  公开（公告）日：2022-05-05

  A bio-electrode composition contains (A) a reaction composite of an ionic polymer material and a carbon particle. The component (A) contains the carbon particle bonding to the polymer containing a repeating unit having a structure selected from the group consisting of salts of ammonium, lithium, sodium, potassium, and silver formed with any of fluorosulfonic acid, fluorosulfonimide, and N-carbonyl-fluorosulfonamide. Thus, the present invention provides: a bio-electrode composition capable of forming a living body contact layer for a bio-electrode which is excellent in electric conductivity and biocompatibility, light-weight, and manufacturable at low cost, and which prevents significant reduction in the electric conductivity even when wetted with water or dried; a bio-electrode including a living body contact layer formed of the bio-electrode composition; and a method for manufacturing the bio-electrode.