bis-(2,2,2-trichlorophenyl) 1-phenylprop-2-yl phosphate

• 分子结构分类: 有机化合物 - 苯类化合物 - 苯和取代衍生物
• 英文名称: bis-(2,2,2-trichlorophenyl) 1-phenylprop-2-yl phosphate
• 英文别名: 2-[Oxido-bis(2,2,2-trichloroethoxy)phosphaniumyl]oxypropylbenzene；2-[oxido-bis(2,2,2-trichloroethoxy)phosphaniumyl]oxypropylbenzene
• 化学式: C₁₃H₁₅Cl₆O₄P
• 分子量: 478.951
• InChiKey: APHAZGMXEZNBNU-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  5.6
• 重原子数：
  24
• 可旋转键数：
  8
• 环数：
  1.0
• sp3杂化的碳原子比例：
  0.54
• 拓扑面积：
  50.8
• 氢给体数：
  0
• 氢受体数：
  4

反应信息

• 作为产物：
  描述：

  1-苯基-2-丙醇 、 [3-[Oxido-bis(2,2,2-trichloroethoxy)phosphaniumyl]-1,3-thiazolidin-2-ylidene]cyanamide 在 叔丁基氯化镁 作用下， 以 四氢呋喃 为溶剂， 反应 0.25h， 以78%的产率得到bis-(2,2,2-trichlorophenyl) 1-phenylprop-2-yl phosphate
  参考文献：
  名称：

  3-Phosphono-2-(N-cyanoimino)thiazolidine derivatives, new phosphorylating agents for alcohols

  摘要：

  We have developed new phosphorylating agents, 3-phosphono-2-(N-cyanoimino)-thiazolidine derivatives (3-phosphono-NCTs), which were readily synthesized by phosphorylation of NCT, and transformed primary and secondary alcohols into phosphates in good yield. The transfer of three kinds of dialkylphosphono groups [(PhO)(2)P(O)-, (EtO)(2)P(O)-, (Cl3CCH2O)(2)P(O)-] proceeded in excellent yields. Selective phosphorylation of various alcohols was also accomplished. (C) 2002 Elsevier Science Ltd. All rights reserved.

  DOI：

  10.1016/s0040-4020(02)00312-5

文献信息

• 3-Phosphono-2-(N-cyanoimino)thiazolidine derivatives, new phosphorylating agents for alcohols
  作者：Naoyoshi Maezaki、Akemi Furusawa、Yuki Hirose、Shuji Uchida、Tetsuaki Tanaka

  DOI：10.1016/s0040-4020(02)00312-5

  日期：2002.4

  We have developed new phosphorylating agents, 3-phosphono-2-(N-cyanoimino)-thiazolidine derivatives (3-phosphono-NCTs), which were readily synthesized by phosphorylation of NCT, and transformed primary and secondary alcohols into phosphates in good yield. The transfer of three kinds of dialkylphosphono groups [(PhO)(2)P(O)-, (EtO)(2)P(O)-, (Cl3CCH2O)(2)P(O)-] proceeded in excellent yields. Selective phosphorylation of various alcohols was also accomplished. (C) 2002 Elsevier Science Ltd. All rights reserved.