(2S)-2-[[(2S)-2-amino-4-methylsulfanylbutanoyl]amino]-4-methyl-N-(4-nitrophenyl)pentanamide

• 分子结构分类: 有机化合物 - 有机酸及其衍生物 - 羧酸及其衍生物
• 英文名称: (2S)-2-[[(2S)-2-amino-4-methylsulfanylbutanoyl]amino]-4-methyl-N-(4-nitrophenyl)pentanamide
• 化学式: C17H26N4O4S
• 分子量: 382.5
• InChiKey: XVTXZDCXARAASU-GJZGRUSLSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  1.6
• 重原子数：
  26
• 可旋转键数：
  9
• 环数：
  1.0
• sp3杂化的碳原子比例：
  0.53
• 拓扑面积：
  155
• 氢给体数：
  3
• 氢受体数：
  6

文献信息

• Recombinant S. aureus peptide deformylase
  申请人：——

  公开号：US20020102250A1

  公开（公告）日：2002-08-01

  An S. aureus peptide deformylase iron complex composition, a method of isolating the composition, and a method of using the composition to screen for compounds that interact with a peptide deformylase are provided. The composition of the invention retains greater than about 95% of its catalytic deformylase activity after being stored at a protein concentration of greater than about 10 mg/ml in 50% glycerol at −20° C. for six months.

  一种 金黄色葡萄球菌 提供了一种肽变形酶铁复合物组合物、一种分离该组合物的方法以及一种使用该组合物筛选与肽变形酶相互作用的化合物的方法。本发明的组合物在 50%甘油中以大于约 10 mg/ml 的蛋白质浓度在-20°C 下储存 6 个月后，其催化变形酶活性保持率大于约 95%。
• [EN] RECOMBINANT S.AUREUS PEPTIDE DEFORMYLASE<br/>[FR] S.AUREUS PEPTIDE DEFORMYLASE DE RECOMBINAISON
  申请人：UPJOHN CO

  公开号：WO2002002763A2

  公开（公告）日：2002-01-10

  An S.aureus peptide deformylase iron complex composition, a method of isolating the composition, and a method of using the composition to screen for compounds that interact with a peptide deformylase are provided. The composition of the invention retains greater than about 95 % of its catalytic deformylase activity after being stored at a protein concentration of greater than about 10 mg/ml in 50 % glycerol at -20 °C for six months.