difluoro[pivalamidopyrazinato-O,N]boron

• 分子结构分类: 有机化合物 - 有机杂环化合物 - 二嗪类
• 英文名称: difluoro[pivalamidopyrazinato-O,N]boron
• 英文别名: 8-t-butyl APB；4-Tert-butyl-2,2-difluoro-3-oxa-5,8-diaza-1-azonia-2-boranuidabicyclo[4.4.0]deca-1(6),4,7,9-tetraene
• 化学式: C₉H₁₂BF₂N₃O
• 分子量: 227.022
• InChiKey: BGFNKNOBXYRWPH-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  1.7
• 重原子数：
  16
• 可旋转键数：
  1
• 环数：
  2.0
• sp3杂化的碳原子比例：
  0.44
• 拓扑面积：
  38.4
• 氢给体数：
  0
• 氢受体数：
  6

反应信息

• 作为产物：
  描述：

  N-(吡嗪-2-基)新戊酰胺 在 三氟化硼乙醚 、 N,N-二异丙基乙胺 作用下， 以 二氯甲烷 为溶剂， 以83%的产率得到difluoro[pivalamidopyrazinato-O,N]boron
  参考文献：
  名称：

  Synthesis and fluorescence properties of difluoro[amidopyrazinato-O,N]boron derivatives: a new boron-containing fluorophore

  摘要：

  New boron-containing fluorophores, difluoro[amidopyrazinato-O,N]boron (APB) derivatives, were prepared from amidopyrazines. The fluorescence properties of APB were successfully modulated by an aryl substitution at the C8 position. (C) 2010 Elsevier Ltd. All rights reserved.

  DOI：

  10.1016/j.tetlet.2010.01.072

文献信息

• Synthesis and fluorescence properties of difluoro[amidopyrazinato-O,N]boron derivatives: a new boron-containing fluorophore
  作者：Sojiro Hachiya、Takayuki Inagaki、Daisuke Hashizume、Shojiro Maki、Haruki Niwa、Takashi Hirano

  DOI：10.1016/j.tetlet.2010.01.072

  日期：2010.3

  New boron-containing fluorophores, difluoro[amidopyrazinato-O,N]boron (APB) derivatives, were prepared from amidopyrazines. The fluorescence properties of APB were successfully modulated by an aryl substitution at the C8 position. (C) 2010 Elsevier Ltd. All rights reserved.