nitriloacetic acid trisodium hydrate

• 分子结构分类: 有机化合物 - 有机酸及其衍生物 - 羧酸及其衍生物
• 英文名称: nitriloacetic acid trisodium hydrate
• 英文别名: nitrilotriacetic acid, trisodium salt monohydrate；trisodium nitrilotriacetate monohydrate；Sodium;2-[bis(carboxylatomethyl)amino]acetate;hydrate
• 化学式: C₆H₆NO₆*H₂O*3Na
• 分子量: 275.101
• InChiKey: TUPNLVQGGZIWSO-UHFFFAOYSA-K

计算性质

• 辛醇/水分配系数(LogP)：
  -9.28
• 重原子数：
  15
• 可旋转键数：
  3
• 环数：
  0.0
• sp3杂化的碳原子比例：
  0.5
• 拓扑面积：
  125
• 氢给体数：
  1
• 氢受体数：
  8

反应信息

• 作为反应物：
  描述：

  nitriloacetic acid trisodium hydrate 、 cadmium(II) chloride 以 水 为溶剂， 生成 乙酸酯,2,2',2''-次氮基三-,盐(1:1)镉
  参考文献：
  名称：

  Szabo, Jeffrey P.; Cocivera, Michael, Canadian Journal of Chemistry, 1988, vol. 66, p. 1065 - 1072

  摘要：

  DOI：

文献信息

• Cyano-bridged dinuclear iron complexes in different oxidation states
  作者：Shaohua Gou、Franz Renz、Yutaka Fukuda、Wolfgang Linert

  DOI：10.1016/s0020-1693(99)00003-1

  日期：1999.4

  Two dinuclear iron complexes, bridged via cyano groups, containing units of [Fe(phen)2(CN)2]n (n=0 or +1) and a chelating ligand, the nitrilotriacetic acid anion, have been synthesised. These compounds, containing iron atoms in different and/or the same oxidation states [Fe(II)/Fe(III) (1); Fe(III)/Fe(III) (2)] were characterised by elemental analyses, IR and UV spectra, TGA and DSC thermograms. Mössbauer

  已合成了两个通过氰基桥接的双核铁络合物，其中含有[Fe（phen）2（CN）2 ] n（n = 0或+1）单元和螯合配体次氮基三乙酸根阴离子。这些化合物含有不同和/或相同氧化态的铁原子[Fe（II）/ Fe（III）（1）; Fe（III）/ Fe（III）（2）]通过元素分析，红外光谱和紫外光谱，TGA和DSC热谱图进行了表征。研究并讨论了配合物1的Mössbauer光谱和磁化率。
• The formation of disulfides by the [Fe(nta)Cl2]2− catalyzed air oxidation of thiols and dithiols
  作者：Marc A. Walters、Jacqueline Chaparro、Talha Siddiqui、Florence Williams、Caleb Ulku、Arnold L. Rheingold

  DOI：10.1016/j.ica.2006.03.043

  日期：2006.9

  The complexes (cnt)(2)[Fe(nta)Cl-2], where nta = nitrilotriacetate and cnt = Et4N+ or PyH+, catalyze the air oxidation of thiols to disulfides under ambient conditions. Dithiols are converted to linear and cyclic oligomers that differ in their terminal groups as a function of the counterion, cnt. Cysteine ethyl ester was converted to the corresponding cystine diethylester in high yield. (c) 2006 Elsevier B.V. All rights reserved.
• Ferric iron complexes of dopamine and 5,6-dihydroxyindole with nta, edda, and edta as ancillary ligands
  作者：Jordan Porter、Shelly Arreguin、Cortlandt G. Pierpont

  DOI：10.1016/j.ica.2010.05.011

  日期：2010.10

  Coordination of the neurotransmitter dopamine (DA) and the metal-binding component of neuromelanin 5,6-dihydroxyindole (DHI) with ferric iron has been studied in aqueous solution in the presence of ancillary ligands containing amine nitrogen and carboxylate oxygen donor sites. With nitrilotriacetic acid (nta) and ethylenediamine diacetic acid (edda) coligands, coordination of the catecholate ligands DA and DHI is observed to be complete at physiological pH. The resulting complexes of DA have the characteristic two-component electronic spectrum observed characteristically for L(4)Fe(Cat) complexes. The spectrum obtained with DHI consists of a single broad absorption in the visible region. Both DA and DHI are able to coordinate with Fe(3+) in the presence of edta, displacing carboxylate oxygen donors at pH values just above physiological pH. These results demonstrate the strong affinity of DA and DHI for Fe3+, pointing to in vivo complex formation in neuronal mixtures at physiological pH. (C) 2010 Elsevier B.V. All rights reserved.