oleoyl chloride

• 分子结构分类: 有机化合物 - 有机卤素化合物 - 酰卤
• 英文名称: oleoyl chloride
• 英文别名: oleyl chloride；(Z)-octadec-10-enoyl chloride
• 化学式: C₁₈H₃₃ClO
• 分子量: 300.912
• InChiKey: GYPDFABFZDKSPH-HJWRWDBZSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  8.3
• 重原子数：
  20
• 可旋转键数：
  15
• 环数：
  0.0
• sp3杂化的碳原子比例：
  0.83
• 拓扑面积：
  17.1
• 氢给体数：
  0
• 氢受体数：
  1

反应信息

• 作为反应物：
  描述：

  oleoyl chloride 在 4-二甲氨基吡啶 、 TEA 作用下， 以 二甲基亚砜 为溶剂， 反应 78.0h， 生成 Trimethyl-{2-((Z)-octadec-10-enoyloxy)-4-[((Z)-octadec-9-enyl)oxy]-butyl}-ammonium; bromide
  参考文献：
  名称：

  Synthesis of cationic lipids from 1,2,4-butanetriol

  摘要：

  Starting from 1,2,4-butanetriol, a series of quaternary ammonium lipids with diether, ether/ester, and diester bonds as linkage between the hydrocarbon chains and butane backbone were synthesized for gene delivery. (C) 1998 Elsevier Science Ltd. All rights reserved.

  DOI：

  10.1016/s0040-4039(98)02381-8

文献信息

• Chemical structure of long‐chain esters from “sansa” olive oil
  作者：Giorgio Bianchi、Aldo Tava、Giovanna Vlahov、Nicoletta Pozzi

  DOI：10.1007/bf02540515

  日期：1994.4

  The major objective of this study was to determine the chemical structure of long‐chain esters present in lower‐grade olive oil. The classes of esters composing the hexanediethyl ether (99∶1) extract of the wax fraction from a pomace olive oil were: (i) esters of oleic acid with C₁−C₆ alcohols, (ii) esters of oleic acid with long‐chain aliphatic alcohols in the range C₂₂−C₂₈ and (iii) benzyl alcohol esters of the very long‐chain saturated fatty acids C₂₆ and C₂₈. The analysis and the structure assignments were carried out by gas chromatography coupled with mass spectrometry and by comparison with synthetic authentic model compounds. This work provided precise data on the chemical nature of the wax esters present in olive oil and should represent a means to detect adulteration of higher‐grade olive oil with less expensive pomace olive oil and seed oils.

  摘要 这项研究的主要目的是确定低级橄榄油中长链酯类的化学结构。从果渣橄榄油的蜡馏分中提取的己二乙基醚（99∶1）中的酯类包括(i) 油酸与 C1-C6 脂肪醇的酯，(ii) 油酸与 C22-C28 长链脂肪醇的酯，(iii) C26 和 C28 长链饱和脂肪酸的苄醇酯。分析和结构鉴定是通过气相色谱-质谱联用技术以及与合成的真实模型化合物进行比较而完成的。这项工作提供了有关橄榄油中蜡酯化学性质的精确数据，应该是检测高级橄榄油与价格较低的果渣橄榄油和种子油掺假的一种手段。
• Synthesis of type I and IV cyanolipids
  作者：Mugio Nishizawa、Kenji Adachi、Yuji Hayashi

  DOI：10.1039/c39840001637

  日期：——

  Type I and IV cyanolipids, members of a unique class of plant lipid, have been synthesized efficiently by means of a novel cyanoesterification of aldehydes, and fully characterzed by spectral analysis; an artifical ‘type V’ cyanolipid has also been synthesized.

  I和IV型氰脂脂是植物脂质的一类成员，已通过醛的新型氰基酯化反应高效合成，并通过光谱分析充分表征。还合成了人造的“ V型”氰脂。
• (E)-Phenyl- and -heteroaryl-substituted O-benzoyl-(or acyl)oximes as lipoprotein-associated phospholipase A2 inhibitors
  作者：Tae-Sook Jeong、Mi Jeong Kim、Hana Yu、Kyung Soon Kim、Joong-Kwon Choi、Sung-Soo Kim、Woo Song Lee

  DOI：10.1016/j.bmcl.2004.11.063

  日期：2005.3

  A series of (E)-phenyl- and -heteroaryl- substituted O-benzoyl-(or acyl)oximes 3a-n were synthesized for evaluating their human lipoprotein-associated phospholiphase A(2) (Lp-PLA(2)) inhibitory activities. The less lipophilic derivatives 3a-c showed the most potent in vitro inhibitory activity on human Lp-PLA2. (c) 2004 Elsevier Ltd. All rights reserved.
• ADVANCED FUNCTIONAL BIOCOMPATIBLE FOAM USED AS A HEMOSTATIC AGENT FOR COMPRESSIBLE AND NON-COMPRESSIBLE ACUTE WOUNDS
  申请人：University of Maryland, College Park

  公开号：EP2498820B1

  公开（公告）日：2019-01-09
• US8668899B2
  申请人：——

  公开号：US8668899B2

  公开（公告）日：2014-03-11