3-methoxy-4-(3-trimethylsilanylpropyloxy)benzaldehyde

• 分子结构分类: 有机化合物 - 苯类化合物 - 苯和取代衍生物
• 英文名称: 3-methoxy-4-(3-trimethylsilanylpropyloxy)benzaldehyde
• 英文别名: 3-Methoxy4-(3-trimethylsilanylpropyloxy)benzaldehyde；3-methoxy-4-(3-trimethylsilylpropoxy)benzaldehyde
• 化学式: C₁₄H₂₂O₃Si
• 分子量: 266.412
• InChiKey: HNTPGIFEBNWRJC-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  3.61
• 重原子数：
  18
• 可旋转键数：
  7
• 环数：
  1.0
• sp3杂化的碳原子比例：
  0.5
• 拓扑面积：
  35.5
• 氢给体数：
  0
• 氢受体数：
  3

反应信息

• 作为产物：
  描述：

  (3-氯丙基)三甲基硅烷 、 香草醛 在 potassium carbonate 作用下， 以 N,N-二甲基甲酰胺 为溶剂， 以89%的产率得到3-methoxy-4-(3-trimethylsilanylpropyloxy)benzaldehyde
  参考文献：
  名称：

  Photostabilized sunscreen compositions comprising dibenzoylmethane compounds

  摘要：

  具有改进的光稳定性的局部适用的化妆品/皮肤学防晒霜组合物非常适合增强保护人体皮肤和/或头发免受紫外线A和紫外线B辐射，特别是太阳辐射的损害作用，包括（i）至少一种二苯甲酮类紫外线屏蔽化合物的光保护有效量，以及（ii）至少一种由苯基亚甲基樟脑官能团取代的硅烷或有机硅氧烷的量，用于使所述至少一种二苯甲酮类紫外线屏蔽化合物（i）具有光稳定作用。

  公开号：

  US06200552B1

文献信息

• UV-photoprotective dibenzoylmethane compositions comprising
  申请人：Societe L'Oreal S.A.

  公开号：US05951968A1

  公开（公告）日：1999-09-14

  Topically applicable, stable, UV-photoprotective cosmetic/dermatological compositions well suited for the photoprotection of human skin and/or hair against the damaging effects of UV-A and UV-B irradiation, comprise (a) an effective UV-photoprotecting amount of at least one dibenzoylmethane UV-sunscreen compound and (b) an effective dibenzoylmethane compound (a) photostabilizing amount of at least one benzalmalonate silane having the structural formula (I): ##STR1##

  适用于皮肤和/或头发的光保护的化妆品/皮肤学组合物，具有适用范围广，稳定，UV光保护的特性，可抵御UV-A和UV-B辐射的损伤效应，包括(a)至少一种二苯甲酮类UV防晒化合物的有效UV光保护量和(b)至少一种苯甲酰丙二酸硅烷的有效二苯甲酮类化合物(a)光稳定剂量，其结构式为(I)：##STR1##
• Photostabilized sunscreen compositions comprising dibenzoylmethane compounds and benzylidenecamphor-substituted silanes/organosiloxanes
  申请人：——

  公开号：US20010026789A1

  公开（公告）日：2001-10-04

  Improvedly photostable, topically applicable cosmetic/dermatological sunscreen compositions well suited for enhanced photoprotection of human skin and/or hair against the damaging effects of UV-A and UV-B irradiation, particularly solar radiation, comprise (i) a photoprotecting effective amount of at least one dibenzoylmethane UV-screening compound, and (ii) an amount of at least one silane or organosiloxane substituted by a benzylidenecamphor functional group effective to photostabilize said at least one dibenzoylmethane UV-screening compound (i).

  改善光稳定性，适用于局部使用的化妆品/皮肤保护剂防晒组合物，特别适用于增强对人类皮肤和/或头发光照辐射（特别是太阳辐射）的有害影响的光保护，包括（i）光保护有效量至少为一种二苯甲酰甲烷紫外线筛选化合物，以及（ii）至少一种被苯基亚甲基橙酮官能团取代的硅烷或有机硅氧烷的量，有效地光稳定所述至少一种二苯甲酰甲烷紫外线筛选化合物（i）。
• UV-PHOTOPROTECTIVE DIBENZOYLMETHANE COMPOSITIONS COMPRISING PHOTOSTABILIZING AMOUNTS OF BENZALMALONATE SILANES
  申请人：——

  公开号：US20020016488A1

  公开（公告）日：2002-02-07

  Topically applicable, stable, UV-photoprotective cosmetic/dermatological compositions well suited for the photoprotection of human skin and/or hair against the damaging effects of TV-A and UV-B irradiation, comprise (a) an effective UV-photoprotecting amount of at least one dibenzoylmethane UV-sunscreen compound and (b) an effective dibenzoylmethane compound (a) photostabilizing amount of at least one benzalmalonate silane having the structural formula (I): 1

  适用于局部使用、稳定、具有紫外线光保护作用的化妆品/皮肤科组合物，非常适合用于保护人类皮肤和/或头发免受紫外线A和紫外线B辐射的有害影响，包括(a)至少一种二苯甲酮类紫外线防晒化合物的有效紫外线光保护量和(b)至少一种苯甲酰丙酸酯硅烷的有效二苯甲酮类化合物(a)光稳定化量，其结构式为(I)：1。
• Benzylidenecamphor-substituted silanes/organosiloxanes for use in photostabilizing sunscreen compositions comprising dibenzoylmethane compounds
  申请人：Societe L'Oreal

  公开号：US06429326B1

  公开（公告）日：2002-08-06

  Improvedly photostable, topically applicable cosmetic/dermatological sunscreen compositions well suited for enhanced photoprotection of human skin and/or hair against the damaging effects of UV-A and UV-B irradiation, particularly solar radiation, comprise (i) a photoprotecting effective amount of at least one dibenzoylmethane UV-screening compound, and (ii) an amount of at least one silane or organosiloxane substituted by a benzylidenecamphor functional group effective to photostabilize said at least one dibenzoylmethane UV-screening compound (i). Novel silanes or organosiloxanes substituted by a benzylidenecamphor functional group are also described.

  本发明提供了一种改进的光稳定性、适用于局部使用的化妆品/皮肤保护剂紫外线防晒组合物，特别适用于增强人类皮肤和/或头发对紫外线辐射（特别是太阳辐射）的损伤效应的保护。该组合物包括（i）至少一种二苯甲酰甲烷紫外线屏障化合物的光保护有效量，和（ii）至少一种被苯甲酰亚胺基团取代的硅烷或有机硅氧烷的量，该亚胺基团对于光稳定化至少一种二苯甲酰甲烷紫外线屏障化合物（i）具有有效作用。本发明还描述了一种新型的被苯甲酰亚胺基团取代的硅烷或有机硅氧烷。
• UV-photoprotective dibenzoylmethane compositions comprising photostabilizing amounts of benzalmalonate silanes
  申请人：Societe L′Oreal

  公开号：US06426428B2

  公开（公告）日：2002-07-30

  Topically applicable, stable, UV-photoprotective cosmetic/dermatological compositions well suited for the photoprotection of human skin and/or hair against the damaging effects of UV-A and UV-B irradiation, comprise (a) an effective UV-photoprotecting amount of at least one dibenzoylmethane UV-sunscreen compound and (b) an effective dibenzoylmethane compound (a) photostabilizing amount of at least one benzalmalonate silane having the structural formula (I):

  适用于局部使用、稳定、具有UV光保护作用的化妆品/皮肤科学组合物，非常适合用于保护人类皮肤和/或头发免受UV-A和UV-B辐射的损害。该组合物包含(a)至少一种二苯甲酮类UV防晒化合物的有效UV防晒量，以及(b)至少一种苯丙二酸酯硅烷的有效二苯甲酮类化合物(a)光稳定化量，该硅烷具有结构式(I)。