moellenoside C

• 分子结构分类: 有机化合物 - 脂质和类脂质分子 - 脂肪酰基
• 英文名称: moellenoside C
• 英文别名: selaginellol 4'-O-β-D-glucopyranoside
• 化学式: C₂₆H₃₆O₁₂
• 分子量: 540.565
• InChiKey: GZEPGRBKNLLYLW-KLEGXBNISA-N

计算性质

• 辛醇/水分配系数(LogP)：
  0.32
• 重原子数：
  38.0
• 可旋转键数：
  11.0
• 环数：
  3.0
• sp3杂化的碳原子比例：
  0.54
• 拓扑面积：
  187.76
• 氢给体数：
  7.0
• 氢受体数：
  12.0

反应信息

• 作为反应物：
  描述：

  moellenoside C 在 盐酸 作用下， 以 水 为溶剂， 反应 4.0h， 生成 葡萄糖
  参考文献：
  名称：

  Two new nor-lignans from Selaginella pulvinata (Hook. & Grev.) Maxim and their antihyperglycemic activities

  摘要：

  Two newnor-lignans, pulvin A (1) and moellenoside C (2), along with two known compounds (3-4) were isolated from the whole plant ofSelaginella pulvinate(Hook. & Grev.) Maxim. The structures of the new compounds were established on the basis of spectroscopic data and acid hydrolysis. All the isolates were investigated for their antihyperglycemic activities in 3T3-L1 adipocytes. The results showed that compounds1and2promoted the glucose consumption prominently in 3T3-L1 adipocytes in a dose-response manner. Compound1and2induced 1.14-1.73 folds and 1.03-1.55 folds changes relative to the basal level, respectively, in the concentration range of 12.5 mu M to 50 mu M.

  DOI：

  10.1080/14786419.2020.1779267