2-methyl-2,3-dihydroxybutyl-3-O-β-D-glucopyranoside

• 分子结构分类: 有机化合物 - 脂质和类脂质分子 - 脂肪酰基
• 英文名称: 2-methyl-2,3-dihydroxybutyl-3-O-β-D-glucopyranoside
• 英文别名: linustatin D
• 化学式: C₁₁H₂₂O₇
• 分子量: 266.291
• InChiKey: PBHPODMSAUWXGS-MZLYOKELSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  -2.04
• 重原子数：
  18.0
• 可旋转键数：
  4.0
• 环数：
  1.0
• sp3杂化的碳原子比例：
  1.0
• 拓扑面积：
  119.61
• 氢给体数：
  5.0
• 氢受体数：
  7.0

反应信息

• 作为反应物：
  描述：

  2-methyl-2,3-dihydroxybutyl-3-O-β-D-glucopyranoside 在 盐酸 作用下， 以 水 为溶剂， 反应 1.0h， 生成 葡萄糖
  参考文献：
  名称：

  Cyanogenetic glycosides and simple glycosides from the linseed meal

  摘要：

  Three new cyanogenetic triglycosides linustatins A-C (1-3), and two new simple glycosides linustatins D and E (4 and 5) were isolated from the 70% ethanol extract of flaxseed meal (Linum usitatissimum L.). Their structures were elucidated on the basis of spectroscopic analysis and chemical evidence. All of the isolates showed moderate activities against aldose reductase and weak activities against a-glucosidase, DPP-IV, and FBPase at the same concentrations as the positive control drugs. (C) 2015 Elsevier B.V. All rights reserved.

  DOI：

  10.1016/j.fitote.2015.08.008

文献信息

• Cyanogenetic glycosides and simple glycosides from the linseed meal
  作者：Qing-Yun Yang、Li Song、Ji-Fa Zhang、Zhu-Fang Shen、Quan Liu、Shuai-Nan Liu、Wen-Sheng Zheng、Chun-Suo Yao

  DOI：10.1016/j.fitote.2015.08.008

  日期：2015.10

  Three new cyanogenetic triglycosides linustatins A-C (1-3), and two new simple glycosides linustatins D and E (4 and 5) were isolated from the 70% ethanol extract of flaxseed meal (Linum usitatissimum L.). Their structures were elucidated on the basis of spectroscopic analysis and chemical evidence. All of the isolates showed moderate activities against aldose reductase and weak activities against a-glucosidase, DPP-IV, and FBPase at the same concentrations as the positive control drugs. (C) 2015 Elsevier B.V. All rights reserved.