chlorohexidine triclosan complex

• 分子结构分类: 有机化合物 - 苯类化合物 - 苯和取代衍生物
• 英文名称: chlorohexidine triclosan complex
• 英文别名: chlorhexidine-triclosan；2-[6-[[amino-[[amino-(4-chloroanilino)methylidene]amino]methylidene]amino]hexyl]-1-[amino-(4-chloroanilino)methylidene]guanidine;5-chloro-2-(2,4-dichlorophenoxy)phenol
• 化学式: C₁₂H₇Cl₃O₂*C₂₂H₃₀Cl₂N₁₀
• 分子量: 794.999
• InChiKey: JKQACYIPCOOWTE-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  8.48
• 重原子数：
  51
• 可旋转键数：
  15
• 环数：
  4.0
• sp3杂化的碳原子比例：
  0.18
• 拓扑面积：
  207
• 氢给体数：
  7
• 氢受体数：
  4

反应信息

• 作为反应物：
  描述：

  chlorohexidine triclosan complex 、 2-mercaptopyridine-1-oxide sodium salt 以 水 为溶剂， 生成 chlorohexidine-omadine-triclosan complex
  参考文献：
  名称：

  [EN] ANTIMICROBIAL COMPLEXES
  [FR] COMPLEXES ANTIMICROBIENS

  摘要：

  公开号：

  WO2012012049A3
• 作为产物：
  描述：

  三氯生 、 葡萄糖酸氯己定 在 sodium hydroxide 作用下， 以 水 为溶剂， 生成 chlorohexidine triclosan complex
  参考文献：
  名称：

  [EN] ANTIMICROBIAL COMPLEXES
  [FR] COMPLEXES ANTIMICROBIENS

  摘要：

  公开号：

  WO2012012049A3

文献信息

• PHARMACEUTICAL COMPOSITION AND ITS USE FOR THE PREVENTION AND TREATMENT OF ORAL CAVITY PATHOLOGIES
  申请人：Grossi, Lionello

  公开号：EP3656370A1

  公开（公告）日：2020-05-27

  The invention relates to a pharmaceutical composition comprising lysozyme, dextranase and an essential oil of a plant belonging to the family Myrtaceae for the prevention, treatment and follow-up of pathologies of the oral cavity of infectious, inflammatory, degenerative or autoimmune origin, preferably selected in the group consisting of: gingivitis, periodontitis, aphthous stomatitis, herpetic stomatitis, prosthetic stomatitis, recurrent aphthosis, xerostomia, xerostomia due to Sjögren's syndrome, burning mouth syndrome (BMS), oral candidiasis, inflammatory dermatoses such as oral lichen planus, autoimmune disorders of the mucous membranes such as mucous membrane pemphigoid (MMP), graft-versus-host disease, white tongue, migratory glossitis, desquamative gingivitis due to oral lichen planus, herpes and combinations thereof. The composition is preferably formulated, together with other ingredients, as a mouthwash for oral rinses.

  本发明涉及一种药物组合物，该组合物由溶菌酶、葡聚糖酶和一种桃金娘科植物的精油组成，用于预防、治疗和跟踪口腔感染性、炎症性、退行性或自身免疫性病变，这些病变最好选自以下组别：牙龈炎、牙周炎、口腔炎、疱疹性口腔炎、修复性口腔炎、复发性口臭、口腔干燥症、斯约格伦综合征引起的口腔干燥症、灼热口腔综合征（BMS）、口腔念珠菌病、炎症性皮肤病，如口腔扁平苔藓、粘膜自身免疫性疾病，如粘膜丘疹（MMP）、移植物抗宿主病、白舌、移行性舌炎、口腔扁平苔藓引起的脱屑性牙龈炎、疱疹及其组合。 该组合物最好与其他成分一起配制成漱口水，用于口腔冲洗。
• Antimicrobial textile products and method of obtaining thereof
  申请人：YEDITEPE ÜNIVERSITESI

  公开号：US10125453B2

  公开（公告）日：2018-11-13

  The present invention relates to a method of obtaining antifungal, anticandidal and antibacterial textile products. The objective of the present invention is to obtain an antimicrobial product, which enables to reduce the infectious diseases that are transmitted or spread by textile products, reduces extra cost and energy spent for ensuring hygiene, and increases hygienity of disposable textile products. A solution of triclosan, chlorhexidine and disodium octaborate pentahydrate is used in the method of the present invention. The said solution enables the hydrophobic textile products to be transformed into hydrophilic products and thereby enables the antimicrobial agents in the solution to be coded into the textile products.

  本发明涉及一种获得抗真菌、抗念珠菌和抗菌纺织品的方法。本发明的目的是获得一种抗菌产品，它能够减少由纺织品传播或扩散的传染病，减少为确保卫生而花费的额外成本和能源，并提高一次性纺织品的卫生性。本发明的方法中使用了三氯生、洗必泰和五水辛硼酸二钠的溶液。上述溶液可将疏水性纺织品转化为亲水性产品，从而将溶液中的抗菌剂编码到纺织品中。
• EP0874655A4
  申请人：——

  公开号：EP0874655A4

  公开（公告）日：2001-05-02
• TRICLOSAN-CONTAINING MEDICAL DEVICES
  申请人：E.I. DU PONT DE NEMOURS AND COMPANY

  公开号：EP0874655A1

  公开（公告）日：1998-11-04
• ANTIMICROBIAL TEXTILE PRODUCTS AND METHOD OF OBTAINING THEREOF
  申请人：YEDITEPE UNIVERSITESI

  公开号：US20160215442A1

  公开（公告）日：2016-07-28

  The present invention relates to a method of obtaining antifungal, anticandidal and antibacterial textile products. The objective of the present invention is to obtain an antimicrobial product, which enables to reduce the infectious diseases that are transmitted or spread by textile products, reduces extra cost and energy spent for ensuring hygiene, and increases hygienity of disposable textile products. A solution of triclosan, chlorhexidin and disodium octaborate pentahydrate is used in the method of the present invention. The said solution enables the hydrophobic textile products to be transformed into hydrophilic products and thereby enables the antimicrobial agents in the solution to be coded into the textile products.