N'-{2-fluoro-4-methyl-5-[(2,2,2-trifluoroethyl)sulfinyl]phenyl}pyrazine-2-carboximidamide

• 分子结构分类: 有机化合物 - 苯类化合物 - 苯和取代衍生物
• 英文名称: N'-{2-fluoro-4-methyl-5-[(2,2,2-trifluoroethyl)sulfinyl]phenyl}pyrazine-2-carboximidamide
• 英文别名: N'-[2-fluoro-4-methyl-5-(2,2,2-trifluoroethylsulfinyl)phenyl]pyrazine-2-carboximidamide
• 化学式: C₁₄H₁₂F₄N₄OS
• 分子量: 360.335
• InChiKey: WPWBOTNHFJUEBL-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  1.5
• 重原子数：
  24
• 可旋转键数：
  4
• 环数：
  2.0
• sp3杂化的碳原子比例：
  0.21
• 拓扑面积：
  100
• 氢给体数：
  1
• 氢受体数：
  9

反应信息

• 作为产物：
  描述：

  N'-{2-fluoro-4-methyl-5-[(2,2,2-trifluoroethyl)sulfanyl]phenyl}pyrazine-2-carboximidamide 在 disodium hydrogenphosphate 、 potassium dihydrogenphosphate 、 苄基三乙基氯化铵 、 间氯过氧苯甲酸 作用下， 以 氯仿 、 水 为溶剂， 反应 24.0h， 以55 mg的产率得到N'-{2-fluoro-4-methyl-5-[(2,2,2-trifluoroethyl)sulfinyl]phenyl}pyrazine-2-carboximidamide
  参考文献：
  名称：

  N-ARYLAMIDINE-SUBSTITUTED TRIFLUOROETHYL SULFIDE DERIVATIVES AS ACARICIDES AND INSECTICIDES

  摘要：

  本发明涉及公式（I）中的新型N-芳酰胺取代三氟乙基硫醚衍生物，其中X1、X2、X3、X4、R1、R2、R3、n的含义如描述所示—它们作为杀螨剂和杀虫剂用于控制动物害虫，并涉及其制备的过程和中间体。

  公开号：

  US20140315898A1

文献信息

• N-arylamidine-substituted trifluoroethyl sulfide derivatives as acaricides and insecticides
  申请人：BAYER CROPSCIENCE AG

  公开号：US10051861B2

  公开（公告）日：2018-08-21

  The present invention relates to novel N-arylamide-substituted trifluoroethyl sulfide derivatives of the formula (I) in which X1, X2, X3, X4, R1, R2, R3, n have the meanings given in the description—to their use as acaricides and insecticides for controlling animal pests and to processes and intermediates for their preparation.

  本发明涉及式 (I) 的新型 N-芳酰胺取代的三氟乙基硫醚衍生物 其中 X1、X2、X3、X4、R1、R2、R3、n 具有说明中给出的含义--用作控制动物害虫的杀螨剂和杀虫剂，以及制备它们的工艺和中间体。
• Use of n-arylamidine-substituted trifluoroethyl sulphoxide derivatives for controlling pests by watering, droplet application, dip application, soil injection or by treating seed
  申请人：BAYER CROPSCIENCE AKTIENGESELLSCHAFT

  公开号：US11058114B2

  公开（公告）日：2021-07-13

  The present invention relates to the use of compounds of the formula (I) in which R1, R2, R3, n, X and Y have the meanings given in the description, for controlling animal pests, in particular insects and/or spider mites and/or nematodes, by drenching the soil, by drip application to the soil, by immersing roots, tubers or bulbs, or by soil injection or for treating seed.

  本发明涉及式 (I) 化合物的用途 其中 R1、R2、R3、n、X 和 Y 具有说明中给出的含义，用于控制动物害虫，特别是昆虫和/或蜘蛛螨和/或线虫，方法是淋洗土壤，滴施土壤，浸泡根茎、块茎或鳞茎，或土壤注射，或处理种子。
• N-ARYLAMIDINE-SUBSTITUIERTE TRIFLUOROETHYLSULFID-DERIVATE ALS AKARIZIDE UND INSEKTIZIDE
  申请人：Bayer CropScience AG

  公开号：EP2793578A1

  公开（公告）日：2014-10-29
• USE OF N-ARYLAMIDINE-SUBSTITUTED TRIFLUOROETHYL SULPHOXIDE DERIVATIVES FOR CONTROLLING PESTS BY WATERING, DROPLET APPLICATION, DIP APPLICATION, SOIL INJECTION OR BY TREATING SEED
  申请人：BAYER CROPSCIENCE AKTIENGESELLSCHAFT

  公开号：US20170181430A1

  公开（公告）日：2017-06-29

  The present invention relates to the use of compounds of the formula (I) in which R 1 , R 2 , R 3 , n, X and Y have the meanings given in the description, for controlling animal pests, in particular insects and/or spider mites and/or nematodes, by drenching the soil, by drip application to the soil, by immersing roots, tubers or bulbs, or by soil injection or for treating seed.
• US9642363B2
  申请人：——

  公开号：US9642363B2

  公开（公告）日：2017-05-09