[EN] (1-ADAMANTYLAMINO)PYRIDINES AND METHOD OF THEIR PREPARATION<br/>[FR] (1-ADAMANTYLAMINO)PYRIDINES ET PROCEDE DE PREPARATION ASSOCIE
申请人:FUNDACJA ROZWOJU DIAGNOSTYKI I
公开号:WO2001074778A1
公开(公告)日:2001-10-11
New (1-adamantylamino)pyridines of formula (2) wherein substituents R1, R2, R3, R4 or R5 are adamantylamino group, hydrogen atom, methyl group or halogen atom, the molecule of formula (2) containing one adamantylamino group and a substituent or substituents being methyl groups or halogen atoms at a position different from an-ortho position to the amino group, and the method of preparation of the new compounds. Studies have shown that these compounds stimulate secretion of TNF-α in some neoplastic cell lines.