1-(2-chloro-4-methylphenyl)-1H-pyrrole-2,5-dione

• 分子结构分类: 有机化合物 - 有机杂环化合物 - 吡咯啉
• 英文名称: 1-(2-chloro-4-methylphenyl)-1H-pyrrole-2,5-dione
• 英文别名: 1-(2-chloro-4-methylphenyl)pyrrole-2,5-dione
• 化学式: C₁₁H₈ClNO₂
• mdl: MFCD02172888
• 分子量: 221.64
• InChiKey: NLZKICUMYMYKER-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  2
• 重原子数：
  15
• 可旋转键数：
  1
• 环数：
  2.0
• sp3杂化的碳原子比例：
  0.09
• 拓扑面积：
  37.4
• 氢给体数：
  0
• 氢受体数：
  2

文献信息

• METHOD FOR DOUBLE STRAND SEQUENCING
  申请人：Oxford Nanopore Technologies PLC

  公开号：US20220389481A1

  公开（公告）日：2022-12-08

  Provided herein is a method of sequencing a target double stranded nucleic acid. The method comprises contacting the double stranded nucleic acid with a reagent as described herein to form a construct and sequencing the construct using a single-molecule sequencing technique as described herein. Associated products and kits are further provided.
• [EN] METHOD FOR DOUBLE STRAND SEQUENCING<br/>[FR] PROCÉDÉ DE SÉQUENÇAGE À DOUBLE BRIN
  申请人：OXFORD NANOPORE TECH LTD

  公开号：WO2021099801A1

  公开（公告）日：2021-05-27

  Provided herein is a method of sequencing a target double stranded nucleic acid. The method comprises contacting the double stranded nucleic acid with a reagent as described herein to form a construct and sequencing the construct using a single-molecule sequencing technique as described herein. Associated products and kits are further provided.
• [EN] METHOD OF CHARACTERISING A TARGET POLYPEPTIDE USING A NANOPORE<br/>[FR] PROCÉDÉ DE CARACTÉRISATION D'UN POLYPEPTIDE CIBLE À L'AIDE D'UN NANOPORE
  申请人：OXFORD NANOPORE TECH LTD

  公开号：WO2021111125A1

  公开（公告）日：2021-06-10

  Provided herein are methods of characterising a target polypeptide as it moves with respect to a nanopore. Also provided are related kits, systems and apparatuses for carrying out such methods.
• [EN] METHOD<br/>[FR] PROCÉDÉ
  申请人：OXFORD NANOPORE TECH LTD

  公开号：WO2021111139A1

  公开（公告）日：2021-06-10

  Provided herein is a method of concentrating a tethering complex in a region of an amphiphilic layer, such as a lipid membrane. Also provided herein are methods of assembling a tethering complex; methods of concentrating an analyte in the region of a detector; amphiphilic layers; and arrays and devices for use in the disclosed methods.
• [EN] METHOD OF DETECTING AN ANALYTE IN A MEDIUM COMPRISING A LIGHT SCATTERING CONSTITUENT<br/>[FR] PROCÉDÉ DE DÉTECTION D'UN ANALYTE DANS UN MILIEU COMPRENANT UN CONSTITUANT DE DIFFUSION DE LUMIÈRE
  申请人：KING S COLLEGE LONDON

  公开号：WO2021198695A1

  公开（公告）日：2021-10-07

  The invention provides methods of optically detecting an analyte in a medium as the analyte moves with respect to a nanopore. The analyte may be, for example, a biological molecule such as a polynucleotide or polypeptide. Systems and apparatuses for carrying our such methods are also provided.