phyllanthuoside A

• 分子结构分类: 有机化合物 - 脂质和类脂质分子 - 脂肪酰基
• 英文名称: phyllanthuoside A
• 化学式: C₂₄H₃₀O₁₁
• 分子量: 494.496
• InChiKey: WIYPRFBUEZVQAG-VLFCOLCQSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  0.2
• 重原子数：
  35.0
• 可旋转键数：
  10.0
• 环数：
  3.0
• sp3杂化的碳原子比例：
  0.46
• 拓扑面积：
  164.37
• 氢给体数：
  5.0
• 氢受体数：
  11.0

反应信息

• 作为反应物：
  描述：

  phyllanthuoside A 在 盐酸 作用下， 以 1,4-二氧六环 为溶剂， 反应 8.0h， 生成 D-葡萄糖
  参考文献：
  名称：

  New Phenolic Glycosides fromPhyllanthus cochinchinensis

  摘要：

  Chemical investigation of the whole plants of Phyllanthus cochinchinensis (Euphorbiaceae) led to the isolation of three new phenolic glycosides, phyllanthuosides A-C, together with 12 known compounds. Their structures were established on the basis of extensive spectroscopic analysis and chemical methods. Among them, phyllanthuosides A and B are two of the rare phenolic glycosides, featuring with a C6-C3-C6 skeleton. The absolute configurations of phyllanthuosides A and B were established by calculated electric circular dichroism (ECD) using time dependent density functional theory (TDDFT). The isolates were also tested for their cytotoxicity and antimicrobial activity.

  DOI：

  10.5935/0103-5053.20140127

文献信息

• New Phenolic Glycosides from<i>Phyllanthus cochinchinensis</i>
  作者：Jian-Qiang Zhao、Yan-Ming Wang、Jun-Jiang Lv、Hong-Tao Zhu、Dong Wang、Chong-Ren Yang、Min Xu、Ying-Jun Zhang

  DOI：10.5935/0103-5053.20140127

  日期：——

  Chemical investigation of the whole plants of Phyllanthus cochinchinensis (Euphorbiaceae) led to the isolation of three new phenolic glycosides, phyllanthuosides A-C, together with 12 known compounds. Their structures were established on the basis of extensive spectroscopic analysis and chemical methods. Among them, phyllanthuosides A and B are two of the rare phenolic glycosides, featuring with a C6-C3-C6 skeleton. The absolute configurations of phyllanthuosides A and B were established by calculated electric circular dichroism (ECD) using time dependent density functional theory (TDDFT). The isolates were also tested for their cytotoxicity and antimicrobial activity.