N-ethyl-4-hydroxy-3-methylphenylamide

• 分子结构分类: 有机化合物 - 苯类化合物 - 苯和取代衍生物
• 英文名称: N-ethyl-4-hydroxy-3-methylphenylamide
• 英文别名: N-ethyl-4-hydroxy-3-methylbenzamide
• 化学式: C₁₀H₁₃NO₂
• 分子量: 179.219
• InChiKey: PNMVPZVMNJWRHM-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  1
• 重原子数：
  13
• 可旋转键数：
  2
• 环数：
  1.0
• sp3杂化的碳原子比例：
  0.3
• 拓扑面积：
  49.3
• 氢给体数：
  2
• 氢受体数：
  2

反应信息

• 作为产物：
  描述：

  避蚊胺 以 水 为溶剂， 生成 omega-羟基-避蚊胺 、 N-乙基-3-甲基-苯甲酰胺 、 N-ethyl-4-hydroxy-3-methylphenylamide 、 N,N-diethyl-tetrahydroxy-3-methylphenylamide 、 N,N-二乙基-3-羟基苯甲酰胺 、 N,N-diethyl-4-hydroxy-3-methylphenylamide 、 N,N-diethyl-2-hydroxy-3-methylphenylamide
  参考文献：
  名称：

  Photolytic degradation of N,N-diethyl-m-toluamide in ice and water: Implications in its environmental fate

  摘要：

  The photochemical transformation of N,N-diethyl-m-toluamide (DEET), one of the most widespread and efficient mosquito repellents, has been investigated. Initially, photoinduced DEET degradation was investigated in liquid samples, at 20 degrees C and 0 degrees C, and in ice (-15 degrees C), aimed to simulate all possible photoinduced processes occurring in water and in cold environments. Under UV-illumination, DEET degradation was more efficient in ice than in water. The evaluation of transformation products (TPs) formed during the photolysis in solution and in ice evidences mostly the same degradation products, but with different concentration ratio and some peculiar differences. An hypothesis about what kind of processes may play a role is reported. In solution, the oxidative process mostly involved were (poly)hydroxylation or oxidation of the hydroxyl groups, while in ice N-dealkylation and monohydroxylation prevail. Finally, DEET and its TPs were searched out in snow and river water in wintertime. (C) 2013 Elsevier B.V. All rights reserved.

  DOI：

  10.1016/j.jphotochem.2013.08.001

文献信息

• Photolytic degradation of N,N-diethyl-m-toluamide in ice and water: Implications in its environmental fate
  作者：P. Calza、C. Medana、M. Sarro、C. Baiocchi、C. Minero

  DOI：10.1016/j.jphotochem.2013.08.001

  日期：2013.11

  The photochemical transformation of N,N-diethyl-m-toluamide (DEET), one of the most widespread and efficient mosquito repellents, has been investigated. Initially, photoinduced DEET degradation was investigated in liquid samples, at 20 degrees C and 0 degrees C, and in ice (-15 degrees C), aimed to simulate all possible photoinduced processes occurring in water and in cold environments. Under UV-illumination, DEET degradation was more efficient in ice than in water. The evaluation of transformation products (TPs) formed during the photolysis in solution and in ice evidences mostly the same degradation products, but with different concentration ratio and some peculiar differences. An hypothesis about what kind of processes may play a role is reported. In solution, the oxidative process mostly involved were (poly)hydroxylation or oxidation of the hydroxyl groups, while in ice N-dealkylation and monohydroxylation prevail. Finally, DEET and its TPs were searched out in snow and river water in wintertime. (C) 2013 Elsevier B.V. All rights reserved.