1,4,7,10-tetraoxa-cycloeicosane-11,20-dione

• 分子结构分类: 有机化合物 - 苯丙烷和聚酮 - 大环内酯类和类似物
• 英文名称: 1,4,7,10-tetraoxa-cycloeicosane-11,20-dione
• 英文别名: 1,4,7,10-Tetraoxa-cycloeicosan-11,20-dion；1,4,7,10-Tetraoxacycloicosane-11,20-dione
• 化学式: C₁₆H₂₈O₆
• 分子量: 316.395
• InChiKey: ISIFSGVPPMCMGU-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  2.2
• 重原子数：
  22
• 可旋转键数：
  0
• 环数：
  1.0
• sp3杂化的碳原子比例：
  0.88
• 拓扑面积：
  71.1
• 氢给体数：
  0
• 氢受体数：
  6

反应信息

• 作为产物：
  描述：

  癸二酸 、 三乙二醇 230.0 ℃ 、399.97 Pa 条件下， 生成 1,4,7,10-tetraoxa-cycloeicosane-11,20-dione
  参考文献：
  名称：

  Arbusow; Winogradowa, Izvestiya Akademii Nauk SSSR, Seriya Khimicheskaya, 1952, p. 865,871;engl.Ausg.S.773

  摘要：

  DOI：

文献信息

• Laser probe with replaceable optic fibers
  申请人：Katalyst Surgical, LLC

  公开号：US10245182B2

  公开（公告）日：2019-04-02

  A laser probe with replaceable optic fibers may include a handle, an optic fiber fixture, and a replaceable optic fiber. The replaceable optic fiber may include an optic fiber having an optic fiber distal end and an optic fiber proximal end. The optic fiber may be disposed in a first transitory connector having a first transitory connector distal end and a first transitory connector proximal end wherein the optic fiber distal end extends a fixed distance from the transitory connector distal end. The optic fiber may be disposed in a second transitory connector having a second transitory connector distal end and a second transitory connector proximal end wherein the optic fiber proximal end extends a fixed distance from the second transitory connector distal end. The first transitory connector may be inserted in the handle and the second transitory connector may be inserted in the optic fiber fixture.

  带可更换光纤的激光探头可包括手柄、光纤夹具和可更换光纤。可更换光纤可包括具有光纤远端和光纤近端的光纤。光纤可安装在第一过渡连接器中，该连接器具有第一过渡连接器远端和第一过渡连接器近端，其中光纤远端从过渡连接器远端延伸出固定距离。光纤可安装在第二过渡连接器中，第二过渡连接器具有第二过渡连接器远端和第二过渡连接器近端，其中光纤近端与第二过渡连接器远端之间有固定距离。第一过渡连接器可插入手柄，第二过渡连接器可插入光纤夹具。
• Illuminated cannula
  申请人：Katalyst Surgical, LLC

  公开号：US10646113B2

  公开（公告）日：2020-05-12

  An illuminated cannula may include an illumination tube, a hub, a cannula base, a valve, an illumination source connector, an optic fiber, and an optic fiber guide. The valve may be disposed in the cannula base. The cannula base may be fixed to the hub. The hub may include a hub aperture. The illumination tube may be disposed in the cannula base. The optic fiber guide may be disposed in the hub. The optic fiber may be disposed in the illumination source connector, the hub, the optic fiber guide, and the cannula base. The optic fiber may be optically coupled to the illumination tube. Illumination light from an illumination source may be configured to transmit through the optic fiber and into the illumination tube.

  照明插管可包括照明管、集线器、插管底座、阀门、照明光源连接器、光纤和光纤导轨。阀门可安装在插管底座中。插管底座可固定在轮毂上。轮毂可包括一个轮毂孔。照明管可安装在插管底座中。光导纤维可设置在轮毂中。光纤可设置在照明光源连接器、轮毂、光纤导轨和插管底座中。光纤可与照明管光学耦合。来自照明光源的照明光可配置为通过光纤传输并进入照明管。
• Curved laser probe with single-use optic fiber
  申请人：Katalyst Surgical, LLC

  公开号：US10709504B2

  公开（公告）日：2020-07-14

  A curved laser probe with single-use optic fiber may include a reusable handle, an optic fiber fixture, and a single-use optic fiber. The single-use optic fiber may include an optic fiber having an optic fiber distal end and an optic fiber proximal end. The optic fiber may be disposed in a first transitory connector having a first transitory connector distal end and a first transitory connector proximal end wherein the optic fiber distal end extends a fixed distance from the transitory connector distal end. The optic fiber may be disposed in a second transitory connector having a second transitory connector distal end and a second transitory connector proximal end wherein the optic fiber proximal end extends a fixed distance from the second transitory connector distal end. The first transitory connector may be inserted in the reusable handle and the second transitory connector may be inserted in the optic fiber fixture.

  带一次性光纤的曲面激光探头可包括一个可重复使用的手柄、一个光纤夹具和一根一次性光纤。一次性光纤可包括具有光纤远端和光纤近端的光纤。光纤可安装在第一过渡连接器中，该连接器具有第一过渡连接器远端和第一过渡连接器近端，其中光纤远端从过渡连接器远端延伸出固定距离。光纤可安装在第二过渡连接器中，第二过渡连接器具有第二过渡连接器远端和第二过渡连接器近端，其中光纤近端与第二过渡连接器远端之间有固定距离。第一过渡连接器可插入可重复使用的手柄中，第二过渡连接器可插入光纤夹具中。
• Microsurgical bipolar forceps
  申请人：Kogent Surgical, LLC

  公开号：US10772676B2

  公开（公告）日：2020-09-15

  A microsurgical bipolar forceps may include an actuation structure, a hypodermic tube, a first electrical conductor, and a second electrical conductor. The actuation structure may include an actuation structure distal end, an actuation structure proximal end, and a plurality of actuation limbs. The hypodermic tube may be disposed in the actuation structure. The first electrical conductor may be disposed in the hypodermic tube and the actuation structure wherein the first electrical conductor is electrically connected to a bipolar cord. The second electrical conductor may be disposed in the hypodermic tube and the actuation structure wherein the second electrical conductor is electrically connected to the bipolar cord. A compression of the actuation structure may be configured to decrease a distance between a first jaw of the first electrical conductor and a second jaw of the second electrical conductor.

  显微外科双极镊子可包括致动结构、皮下注射管、第一电导体和第二电导体。致动结构可包括致动结构远端、致动结构近端和多个致动肢。皮下注射管可放置在致动结构中。第一电导体可设置在皮下注射管和驱动结构中，其中第一电导体与双极线电连接。第二导体可设置在皮下注射管和致动结构中，其中第二导体与双极线电连接。致动结构的压缩可配置为减小第一电导体的第一钳口与第二电导体的第二钳口之间的距离。
• Reusable instrument handle with single-use tip
  申请人：Katalyst Surgical, LLC

  公开号：US11160935B2

  公开（公告）日：2021-11-02

  A reusable instrument handle with single-use tip may include an instrument tip and an instrument handle. The instrument tip may include an outer base, a nosecone, a pressure mechanism, a hypodermic tube, a blank, a fixation mechanism, and a tip cover. The instrument handle may include an actuation structure, a fixation mechanism receptacle, and an instrument tip housing. The fixation mechanism and the fixation mechanism receptacle may be configured to temporarily fix the instrument tip in the instrument tip housing. A compression of the actuation structure may be configured to actuate the hypodermic tube relative to the blank. The instrument tip may be removed from the instrument tip housing after use by removing the fixation mechanism from the fixation mechanism receptacle.

  带一次性针尖的可重复使用器械手柄可包括一个针尖和一个器械手柄。器械尖端可包括一个外底座、一个气囊、一个压力机构、一个皮下注射管、一个坯料、一个固定机构和一个尖端盖。器械手柄可包括一个致动结构、一个固定机构容器和一个器械尖端外壳。固定机构和固定机构托架可用于将器械尖端临时固定在器械尖端外壳中。致动结构的压缩可配置为相对于坯体致动皮下注射管。使用后，可将固定机构从固定机构容器中取出，从而将器械尖端从器械尖端外壳中取出。