4-amino-1-phenylpyrazolidine-3,5-dione

• 分子结构分类: 有机化合物 - 有机酸及其衍生物 - 羧酸及其衍生物
• 英文名称: 4-amino-1-phenylpyrazolidine-3,5-dione
• 英文别名: 4-amino-1-phenyl-pyrazolidin-3,5-dione；4-Amino-1-phenyl-pyrazolidin-3,5-dion；4-Amino-1-phenylpyrazolidine-3,5-dione
• 化学式: C₉H₉N₃O₂
• 分子量: 191.189
• InChiKey: YHRPDSRWEDJPTH-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  -0.1
• 重原子数：
  14
• 可旋转键数：
  1
• 环数：
  2.0
• sp3杂化的碳原子比例：
  0.11
• 拓扑面积：
  75.4
• 氢给体数：
  2
• 氢受体数：
  3

反应信息

• 作为反应物：
  描述：

  4-amino-1-phenylpyrazolidine-3,5-dione 、 依达拉奉 在 水 、 sodium nitrite 、 sodium acetate 作用下， 以 水 为溶剂， 生成 4-(2-(5-hydroxyl-3-methyl-1-phenyl-1H-pyrazol-4-yl)hydrazono)-1-phenylpyrazolidine-3,5-dione
  参考文献：
  名称：

  二氧化硅包覆磁铁矿纳米颗粒负载酸性离子液体催化吡唑啉酮衍生物偶氮染料的合成及光谱表征

  摘要：

  摘要 以二氧化硅包覆的磁铁矿纳米颗粒负载的酸性离子液体为酸性催化剂，在室温和无溶剂条件下，通过不同吡唑啉酮胺衍生物的重氮化反应，通过高效快速的方法制备了新型吡唑啉酮类偶氮染料。使适应。本方法的吸引人的优点包括反应时间短、条件更温和、更清洁、纯度和产率更高、产品易于分离、更容易的后处理程序和更少的废物或污染产生。这种催化剂很容易被外部磁铁分离，回收的催化剂可以重复使用几次，而没有任何显着的活性损失。因此，该方法提供了优于现有方法的改进协议。

  DOI：

  10.1016/j.molstruc.2017.10.091
• 作为产物：
  描述：

  4-hydroxyimino-1-phenylpyrazolidine-3,5-dione 在 氯化铵 、 锌 作用下， 以 甲醇 为溶剂， 以0.97 g的产率得到4-amino-1-phenylpyrazolidine-3,5-dione
  参考文献：
  名称：

  Simple route to a novel class of pyrazolidine-3,5-dione based azo dyes

  摘要：

  We report an easiest synthesis strategy of a new class of synthetic dyes by coupling of functionalized pyrazolidine-3,5-dione derivatives via diazotization reaction with aromatic diamine for the azoic dyes or via dimerization reaction to synthesize the H chromophore dyes. Electron delocalization between the two coupled components has been studied using UV-vis spectroscopy, infrared, and NMR spectroscopy. In addition, the formation mechanism of such compounds has been discussed. (C) 2010 Elsevier Ltd. All rights reserved.

  DOI：

  10.1016/j.tetlet.2010.08.002

文献信息

• A facile route to the new triazene dyes based on substituted pyrazolidin-3,5-dione derivatives
  作者：Jalal Isaad、Fouad Malek、Ahmida El Achari

  DOI：10.1016/j.dyepig.2011.07.023

  日期：2012.3

  coupling functionalized pyrazolidin-3,5-dione derivatives, to various heteroarene azides in excellent yields (98%). Electron delocalization between the two coupled components of these triazene dyes was studied using UV–vis spectra and NMR spectroscopy. Their thermolysis was investigated and by using an isotopically labeled triazene, the mechanism decomposition reaction was also identified. The protolysis

  几种取代的三氮烯染料是通过将官能化的吡唑烷定3,5-二酮衍生物与各种杂芳基叠氮化物偶联而制得的，产率极高（98％）。使用紫外可见光谱和核磁共振波谱研究了这些三氮烯染料的两个偶合组分之间的电子离域。研究了它们的热分解，并通过使用同位素标记的三氮烯，还确定了其分解反应的机理。对这些三氮烯的质子分解进行了评估，结果表明它们是高度稳定的，甚至在强酸性介质中也是如此。
• Conrad; Zart, Chemische Berichte, 1906, vol. 39, p. 2283
  作者：Conrad、Zart

  DOI：——

  日期：——
• Simple route to a novel class of pyrazolidine-3,5-dione based azo dyes
  作者：Jalal Isaad、Anne Perwuelz

  DOI：10.1016/j.tetlet.2010.08.002

  日期：2010.10

  We report an easiest synthesis strategy of a new class of synthetic dyes by coupling of functionalized pyrazolidine-3,5-dione derivatives via diazotization reaction with aromatic diamine for the azoic dyes or via dimerization reaction to synthesize the H chromophore dyes. Electron delocalization between the two coupled components has been studied using UV-vis spectroscopy, infrared, and NMR spectroscopy. In addition, the formation mechanism of such compounds has been discussed. (C) 2010 Elsevier Ltd. All rights reserved.
• Synthesis and spectroscopic characterization of azoic dyes based on pyrazolone derivatives catalyzed by an acidic ionic liquid supported on silica-coated magnetite nanoparticle
  作者：Jalal Isaad、Ahmida El Achari

  DOI：10.1016/j.molstruc.2017.10.091

  日期：2018.2

  Abstract Novel family of azoic dyes pyrazolone based were prepared by an efficient and rapid methodology through diazotization reaction of different pyrazolone amine derivatives, in the presence of acidic ionic liquid supported on silica-coated magnetite nanoparticles as acidic catalyst at room temperature and under solvent-free conditions. The attractive advantages of the present process include short

  摘要 以二氧化硅包覆的磁铁矿纳米颗粒负载的酸性离子液体为酸性催化剂，在室温和无溶剂条件下，通过不同吡唑啉酮胺衍生物的重氮化反应，通过高效快速的方法制备了新型吡唑啉酮类偶氮染料。使适应。本方法的吸引人的优点包括反应时间短、条件更温和、更清洁、纯度和产率更高、产品易于分离、更容易的后处理程序和更少的废物或污染产生。这种催化剂很容易被外部磁铁分离，回收的催化剂可以重复使用几次，而没有任何显着的活性损失。因此，该方法提供了优于现有方法的改进协议。