3,11-di-O-galloylbergenin

• 分子结构分类: 有机化合物 - 苯类化合物 - 苯和取代衍生物
• 英文名称: 3,11-di-O-galloylbergenin
• 英文别名: [(2R,3S,4R,4aR,10bS)-4,8,10-trihydroxy-9-methoxy-6-oxo-3-(3,4,5-trihydroxybenzoyl)oxy-3,4,4a,10b-tetrahydro-2H-pyrano[3,2-c]isochromen-2-yl]methyl 3,4,5-trihydroxybenzoate
• 化学式: C₂₈H₂₄O₁₇
• 分子量: 632.488
• InChiKey: PAXXSDYZMXMQHW-AMPCSZDDSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  0.8
• 重原子数：
  45
• 可旋转键数：
  8
• 环数：
  5.0
• sp3杂化的碳原子比例：
  0.25
• 拓扑面积：
  279
• 氢给体数：
  9
• 氢受体数：
  17

反应信息

• 作为反应物：
  描述：

  3,11-di-O-galloylbergenin 在 单宁酶 、 水 作用下， 反应 8.0h， 生成 岩白菜素
  参考文献：
  名称：

  A NEW GALLOYLBERGENIN FROM BERGENIA cRASSIFOLIA WITH ANTI-LIPID DROPLET ACCUMULATION ACTIVITY

  摘要：

  A new bergenin derivative, 3,11-di-O-galloylbergenin (1) was isolated from the roots of Bergenia crassifolia together with four known related compounds. Their structures were elucidated by spectroscopic and chemical analysis. The new galloylbergenin showed a moderate anti-lipid droplet accumulation activity.

  DOI：

  10.3987/com-12-s(n)110

文献信息

• A NEW GALLOYLBERGENIN FROM BERGENIA cRASSIFOLIA WITH ANTI-LIPID DROPLET ACCUMULATION ACTIVITY
  作者：Hiroshi Morita、Jenis Janar、Liang Fang、Chin Piow Wong、Toshio Kaneda、Yusuke Hirasawa、Burasheva Gauhar Shahmanovna、Abilov Zharylkasyn Abduahitovich

  DOI：10.3987/com-12-s(n)110

  日期：——

  A new bergenin derivative, 3,11-di-O-galloylbergenin (1) was isolated from the roots of Bergenia crassifolia together with four known related compounds. Their structures were elucidated by spectroscopic and chemical analysis. The new galloylbergenin showed a moderate anti-lipid droplet accumulation activity.