N-hydroxylaminobenzene-4-sulfonic acid

• 分子结构分类: 有机化合物 - 苯类化合物 - 苯和取代衍生物
• 英文名称: N-hydroxylaminobenzene-4-sulfonic acid
• 英文别名: sulfanilic acid；4-(hydroxyamino)benzenesulfonic acid
• 化学式: C₆H₇NO₄S
• 分子量: 189.192
• InChiKey: MSYVHZXMLZBEIF-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  0.2
• 重原子数：
  12
• 可旋转键数：
  2
• 环数：
  1.0
• sp3杂化的碳原子比例：
  0.0
• 拓扑面积：
  95
• 氢给体数：
  3
• 氢受体数：
  5

反应信息

• 作为产物：
  描述：

  对氨基苯磺酸 在 peroxomonosulfate(1-) 作用下， 以 水 、 溶剂黄146 为溶剂， 生成 N-hydroxylaminobenzene-4-sulfonic acid
  参考文献：
  名称：

  Abdul Jameel; Maruthamuthu, Journal of the Indian Chemical Society, 1998, vol. 75, # 6, p. 368 - 370

  摘要：

  DOI：

文献信息

• Chloraminometric and bromaminometric oxidation of sulfanilic acid in alkaline medium: A comparative kinetic and mechanistic study
  作者：Puttaswamy、R. V. Jagadeesh

  DOI：10.1002/kin.20138

  日期：2006.1

  The kinetics of oxidation of sulfanilic acid (SAA) by chloramine-B (CAB) and bromamine-B (BAB) has been investigated in alkaline medium at 35 ± 0.1°C. The oxidation reaction follows identical kinetics in the case of both the oxidants with first-order dependence on each [oxidant]o and [SAA]o and an inverse first-order dependence on [OH−]. The variation of ionic strength, dielectric constant of the medium

  已在 35 ± 0.1°C 的碱性介质中研究了氯胺-B (CAB) 和溴胺-B (BAB) 对磺胺酸 (SAA) 的氧化动力学。在氧化剂的情况下，氧化反应遵循相同的动力学，一级依赖于每个[氧化剂]o 和[SAA]o，一级依赖于[OH-]。离子强度的变化、介质的介电常数、反应产物（苯磺酰胺）和卤离子的加入对反应速率没有显着影响。在 H2O-D2O 混合物中对 CAB 和 BAB 进行的质子库存研究已用于计算同位素分馏因子。该反应已在不同温度下进行了研究，复合反应的活化参数已从 Arrhenius 图计算出来。N-Hydroxylaminobenzo-4-sulfonic 酸被确定为SAA 的氧化产物从IR 和GC-MS 分析。提出了与动力学结果一致的机制，其中 PhSO2NHX（X = Cl 或 Br）在限速步骤中与底物相互作用。推导出一个合适的比率定律。与 CAB 相比，BAB 中磺胺酸的
• Degradation of sulfadiazine antibiotics by water falling film dielectric barrier discharge
  作者：Shao-Peng Rong、Ya-Bing Sun、Ze-Hua Zhao

  DOI：10.1016/j.cclet.2013.11.003

  日期：2014.1

  aqueous solution. The various parameters that affect the degradation of sulfadiazine and the proposed evolutionary process were investigated. The results indicated that the inner concentrations of 10 mg/L sulfadiazine can be all removed within 30 min. The optimum pH value was 9.10 and both strong acidic and alkaline solution conditions were not suitable for the degradation. The degradation of sulfadiazine can be enhanced by the addition of hydrogen radical scavengers, but be inhibited by adding hydroxyl radical scavengers. The water falling film dielectric barrier discharge was rather ineffective in mineralization, because of the intermediates were recalcitrant to be degraded. The existence of Fe2+ and CCl4 in the liquid phase can promote the degradation and mineralization of sulfadiazine. It was found that the degradation of SDZ was enhanced by CCl4 was mainly because of the increase of 'OH due to the reaction of CCI4 with center dot H that reduce the chances of their recombination with center dot OH. Based on the 8 intermediate products identified by LC-MS, the proposed evolution of the degradation process was investigated. (C) 2013 Ya-Bing Sun. Published by Elsevier B.V. on behalf of Chinese Chemical Society. All rights reserved.
• CCR-3 RECEPTOR ANTAGONISTS VII
  申请人：F. HOFFMANN-LA ROCHE AG

  公开号：EP1453804B1

  公开（公告）日：2007-08-22
• Abdul Jameel; Maruthamuthu, Journal of the Indian Chemical Society, 1998, vol. 75, # 6, p. 368 - 370
  作者：Abdul Jameel、Maruthamuthu

  DOI：——

  日期：——