phenol-2PO

• 分子结构分类: 有机化合物 - 苯类化合物 - 苯酚醚
• 英文名称: phenol-2PO
• 英文别名: 1-[(1-Phenoxypropan-2-yl)oxy]propan-2-ol；1-(1-phenoxypropan-2-yloxy)propan-2-ol
• 化学式: C₁₂H₁₈O₃
• 分子量: 210.273
• InChiKey: OCJBPJXCJNSRJY-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  1.9
• 重原子数：
  15
• 可旋转键数：
  6
• 环数：
  1.0
• sp3杂化的碳原子比例：
  0.5
• 拓扑面积：
  38.7
• 氢给体数：
  1
• 氢受体数：
  3

反应信息

• 作为产物：
  描述：

  methyloxirane 、 苯酚 在 anion exchange resin A (Cl-type) 作用下， 反应 12.0h， 以94.4%的产率得到1-苯氧基-丙醇
  参考文献：
  名称：

  Aromatic ethers and process for producing aromatic ethers

  摘要：

  根据一个生产过程，芳香醚可通过将酚与环氧化合物反应，并使用阴离子交换树脂作为催化剂来生产。根据另一个生产过程，具有醇羟基的芳香醚可通过结晶纯化步骤，使用溶剂进行结晶纯化，其溶解度参数范围为7.5至12.5进行生产。此外，根据另一个生产过程，可生产具有醇羟基的芳香醚，其中芳香醚中金属的含量小于100ppm，卤素元素的含量小于100ppm。

  公开号：

  US20040181099A1

文献信息

• BITTER TASTE MODIFIERS INCLUDING SUBSTITUTED 1-BENZYL-3-(1-(ISOXAZOL-4-YLMETHYL)-1H-PYRAZOL-4-YL)IMIDAZOLIDINE-2,4-DIONES AND COMPOSITIONS THEREOF
  申请人：SENOMYX, INC.

  公开号：US20160376263A1

  公开（公告）日：2016-12-29

  The present invention includes compounds and compositions known to modify the perception of bitter taste, and combinations of said compositions and compounds with additional compositions, compounds, and products. Exemplary compositions comprise one or more of the following: cooling agents; inactive drug ingredients; active pharmaceutical ingredients; food additives or foodstuffs; flavorants, or flavor enhancers; food or beverage products; bitter compounds; sweeteners; bitterants; sour flavorants; salty flavorants; umami flavorants; plant or animal products; compounds known to be used in pet care products; compounds known to be used in personal care products; compounds known to be used in home products; pharmaceutical preparations; topical preparations; cannabis-derived or cannabis-related products; compounds known to be used in oral care products; beverages; scents, perfumes, or odorants; compounds known to be used in consumer products; silicone compounds; abrasives; surfactants; warming agents; smoking articles; fats, oils, or emulsions; and/or probiotic bacteria or supplements.

  本发明涵盖已知用于改变苦味感知的化合物和组合物，以及所述组合物和化合物与额外的组合物、化合物和产品的组合。示例组合物包括以下一种或多种：冷却剂；无活性药物成分；活性药用成分；食品添加剂或食品；调味剂或调味增强剂；食品或饮料产品；苦味化合物；甜味剂；苦味剂；酸味调味剂；咸味调味剂；鲜味调味剂；植物或动物产品；已知用于宠物护理产品中的化合物；已知用于个人护理产品中的化合物；已知用于家用产品中的化合物；制药制剂；局部制剂；大麻衍生或与大麻相关的产品；已知用于口腔护理产品中的化合物；饮料；香味、香水或除臭剂；已知用于消费品中的化合物；硅化合物；磨料；表面活性剂；发热剂；吸烟物品；脂肪、油脂或乳化剂；和/或益生菌或补充剂。
• [EN] PROCESS FOR PRODUCING LOW VOC COALESCING AIDS<br/>[FR] PROCÉDÉ DE PRODUCTION D'AGENTS DE COALESCENCE À FAIBLE TENEUR EN COV
  申请人：DOW GLOBAL TECHNOLOGIES LLC

  公开号：WO2015200088A1

  公开（公告）日：2015-12-30

  A process comprising reacting a mono- or di-carboxylic acid and/or acid anhydride with a glycol ether in the presence of phosphoric acid to produce a glycol ether ester product having low color and low VOC content.

  一种包括在磷酸存在下，将单羧酸或二羧酸及/或酸酐与乙二醇醚反应以生产具有低色度和低VOC含量的乙二醇醚酯产品的过程。
• COMPOUNDS USEFUL AS MODULATORS OF TRPM8
  申请人：Senomyx, Inc.

  公开号：US20170096418A1

  公开（公告）日：2017-04-06

  The present disclosure relates to compounds which are useful as cooling sensation compounds.

  本公开涉及作为冷感化合物有用的化合物。
• FLUORINE-CONTAINING URETHANE (METH)ACRYLATE, CURABLE COMPOSITION, AND ANTIREFLECTIVE FILM
  申请人：DIC CORPORATION

  公开号：US20160208131A1

  公开（公告）日：2016-07-21

  It is an object of the present invention to provide a urethane (meth)acrylate that enables formation of a cured layer having a low reflectance and excellent excoriation resistance, a curable composition produced by using the same, and an antireflective film. In particular, there is provided a fluorine-containing urethane (meth)acrylate represented by General Formula (I) and having a fluorine atom content ranging from 25 to 60 mass % (where R 1 and R 2 each represent a specific fluorinated alkyl group, R 3 and R 4 each represent a hydrogen atom or a methyl group, A represents a trivalent linking group represented by any of Structural Formulae (A1) to (A4), and X and Y each independently represent a divalent linking group represented by any of Structural Formulae (a) to (c)) [in Structural Formula (c), R5 represents an alkyl group having 1 to 6 carbon atoms].

  本发明旨在提供一种尿素（甲基）丙烯酸酯，能够形成具有低反射和优异耐磨性的固化层，以及使用该尿素（甲基）丙烯酸酯制备的可固化组合物和防反射膜。特别地，提供了一种含氟尿素（甲基）丙烯酸酯，其由通式（I）表示，其氟原子含量范围为25至60质量％（其中，R1和R2各代表特定的氟化烷基，R3和R4各代表氢原子或甲基基团，A代表由结构式（A1）至（A4）任一表示的三价连接基团，X和Y各自独立地代表由结构式（a）至（c）任一表示的二价连接基团）[在结构式（c）中，R5代表具有1至6个碳原子的烷基基团]。
• [EN] PROCESS FOR THE CONTINUOUS PRODUCTION OF HIGH PURITY PHENOLIC GLYCOL ETHER<br/>[FR] PROCÉDÉ DE FABRICATION EN CONTINU D'ÉTHERS DE GLYCOLS PHÉNOLIQUES DE PURETÉ ÉLEVÉE
  申请人：DOW GLOBAL TECHNOLOGIES INC

  公开号：WO2009076275A1

  公开（公告）日：2009-06-18

  Phenolic glycol ethers, e.g., ethylene glycol phenyl ether, are prepared by a continuous, nonaqueous process comprising the steps of (A) contacting under isothermal reactive conditions in a first reactor or reaction zone an alkylene oxide, e.g., ethylene oxide, with (i) a stoichiometric molar excess of a phenolic compound, e.g., phenol, and (ii) a catalytic amount of a base, e.g., sodium hydroxide, homogeneously dispersed throughout the phenolic compound, to form a first intermediate phenolic glycol ether product, (Bj transferring the first intermediate phenolic glycol ether product to a second reactor or reaction zone, and ( C) subjecting the first intermediate phenolic glycol ether product to adiabatic reactive conditions in the second reactor or reaction zone to form a second intermediate phenolic glycol ether product comprising phenolic glycol ether, unreacted phenolic compound, catalyst, water and byproduct glycols. In addition, the mono-/di-product weight ratio can be adjusted by increasing or decreasing the amount of base catalyst employed.

  酚醚类化合物，例如乙二醇苯醚，通过连续的非水过程制备，包括以下步骤：（A）在第一反应器或反应区域中，在等温反应条件下接触烷基氧化物，例如乙氧基，与（i）过量的苯酚化合物，例如苯酚，和（ii）催化剂量的碱，例如氢氧化钠，均匀分散在苯酚中，以形成第一中间酚醚产物；（B）将第一中间酚醚产物转移至第二反应器或反应区域；（C）在第二反应器或反应区域中，对第一中间酚醚产物进行绝热反应条件，以形成第二中间酚醚产物，其中包括酚醚，未反应的苯酚化合物，催化剂，水和副产物醇。此外，可以通过增加或减少使用的碱催化剂量来调整单/双产物重量比。