bis[prolinate-N,O]Zn

• 分子结构分类: 有机化合物 - 有机酸及其衍生物 - 羧酸及其衍生物
• 英文名称: bis[prolinate-N,O]Zn
• 英文别名: Zn[Pro]2；ZINC;pyrrolidine-2-carboxylate
• 化学式: C₁₀H₁₆N₂O₄Zn
• 分子量: 293.638
• InChiKey: JOUZZYMOTNQWPM-UHFFFAOYSA-L

计算性质

• 辛醇/水分配系数(LogP)：
  -3.03
• 重原子数：
  17
• 可旋转键数：
  0
• 环数：
  2.0
• sp3杂化的碳原子比例：
  0.8
• 拓扑面积：
  104
• 氢给体数：
  2
• 氢受体数：
  6

反应信息

• 作为产物：
  描述：

  zinc diacetate 、 L-脯氨酸 在 三乙胺 作用下， 以 水 、 甲醇 为溶剂， 反应 0.92h， 以95%的产率得到bis[prolinate-N,O]Zn
  参考文献：
  名称：

  Zn[aminoacid]2 hybrid materials applied as heterogeneous catalysts in the synthesis of β-enaminones

  摘要：

  Hybrid materials have seized attention from scientific community mainly as heterogenic catalysts in organic reactions on a large scale succeeding in some organic compounds with high yields. One of the most important classes of hybrid materials used for this purpose involves the complexation of Zn and aminoacids. Herein, we introduced Zn[Pro](2) and Zn[Gly](2) in the synthesis of several beta-enaminones via solvent free protocol and using an ultrasound device. (C) 2014 Elsevier Ltd. All rights reserved.

  DOI：

  10.1016/j.tetlet.2014.05.122
• 作为试剂：
  描述：

  乙酰乙酸乙酯 、 甲氧苯胺 在 bis[prolinate-N,O]Zn 作用下， 以 neat (no solvent) 为溶剂， 反应 1.0h， 以75%的产率得到ethyl (Z)-3-(4-methoxyanilino)-2-butenoate
  参考文献：
  名称：

  Zn[aminoacid]2 hybrid materials applied as heterogeneous catalysts in the synthesis of β-enaminones

  摘要：

  Hybrid materials have seized attention from scientific community mainly as heterogenic catalysts in organic reactions on a large scale succeeding in some organic compounds with high yields. One of the most important classes of hybrid materials used for this purpose involves the complexation of Zn and aminoacids. Herein, we introduced Zn[Pro](2) and Zn[Gly](2) in the synthesis of several beta-enaminones via solvent free protocol and using an ultrasound device. (C) 2014 Elsevier Ltd. All rights reserved.

  DOI：

  10.1016/j.tetlet.2014.05.122