二乙基二甲基氢氧化铵 | 95500-19-9

• 物质功能分类: 化学试剂 - 有机试剂 - 酰亚胺
• 分子结构分类: 有机化合物 - 有机氮化合物
• 中文名称: 二乙基二甲基氢氧化铵
• 中文别名: 氢氧化-N-乙基-N,N-二甲基-乙铵
• 英文名称: diethyldimethylammonium hydroxide
• 英文别名: diethyl-dimethyl-ammonium; hydroxide；Diaethyl-dimethyl-ammonium; Hydroxid；diethyl(dimethyl)azanium;hydroxide
• CAS: 95500-19-9
• 化学式: C₆H₁₆N*HO
• 分子量: 119.207
• InChiKey: JQDCIBMGKCMHQV-UHFFFAOYSA-M

物化性质

• 密度：
  1.010

计算性质

• 辛醇/水分配系数(LogP)：
  0.93
• 重原子数：
  8
• 可旋转键数：
  2
• 环数：
  0.0
• sp3杂化的碳原子比例：
  1.0
• 拓扑面积：
  1
• 氢给体数：
  1
• 氢受体数：
  1

安全信息

• 危险品标志：
  C
• 安全说明：
  S26,S36/37/39,S45
• 危险类别码：
  R34
• WGK Germany：
  3
• 海关编码：
  2923900090
• 危险标志：
  GHS05
• 危险品运输编号：
  UN 3267 8/PG 2
• 危险性描述：
  H314
• 危险性防范说明：
  P280,P305 + P351 + P338,P310
• 储存条件：
  室温

SDS

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SECTION 1: Identification of the substance/mixture and of the company/undertaking
Product identifiers
Product name : Diethyldimethylammonium hydroxide solution
REACH No. : A registration number is not available for this substance as the substance
or its uses are exempted from registration, the annual tonnage does not
require a registration or the registration is envisaged for a later
registration deadline.
Relevant identified uses of the substance or mixture and uses advised against
Identified uses : Laboratory chemicals, Manufacture of substances

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SECTION 2: Hazards identification
Classification of the substance or mixture
Classification according to Regulation (EC) No 1272/2008
Skin corrosion (Category 1A), H314
For the full text of the H-Statements mentioned in this Section, see Section 16.
Classification according to EU Directives 67/548/EEC or 1999/45/EC
C Corrosive R34
For the full text of the R-phrases mentioned in this Section, see Section 16.
Label elements
Labelling according Regulation (EC) No 1272/2008
Pictogram
Signal word Danger
Hazard statement(s)
H314 Causes severe skin burns and eye damage.
Precautionary statement(s)
P280 Wear protective gloves/ protective clothing/ eye protection/ face
protection.
P305 + P351 + P338 IF IN EYES: Rinse cautiously with water for several minutes. Remove
contact lenses, if present and easy to do. Continue rinsing.
P310 Immediately call a POISON CENTER or doctor/ physician.
Supplemental Hazard none
Statements
According to European Directive 67/548/EEC as amended.
Hazard symbol(s) C Corrosive
R-phrase(s)
R34 Causes burns.
S-phrase(s)
S26 In case of contact with eyes, rinse immediately with plenty of water and
seek medical advice.
S36/37/39 Wear suitable protective clothing, gloves and eye/face protection.
S45 In case of accident or if you feel unwell, seek medical advice immediately
(show the label where possible).
Other hazards - none

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SECTION 3: Composition/information on ingredients
Mixtures
Chemical characterization : Natural product
Formula : C6H17NO
Molecular Weight : 119,21 g/mol
Hazardous ingredients according to Regulation (EC) No 1272/2008
Component Classification Concentration
Ethanaminium, N-ethyl-N,N-dimethyl-, hydroxide (1:1)
CAS-No. 95500-19-9 Acute Tox. 4; Skin Corr. 1A; 20 - 25 %
H302 + H312, H314
Hazardous ingredients according to Directive 1999/45/EC
Component Classification Concentration
Ethanaminium, N-ethyl-N,N-dimethyl-, hydroxide (1:1)
CAS-No. 95500-19-9 C, R34 20 - 25 %
For the full text of the H-Statements and R-Phrases mentioned in this Section, see Section 16

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SECTION 4: First aid measures
Description of first aid measures
General advice
Consult a physician. Show this safety data sheet to the doctor in attendance.
If inhaled
If breathed in, move person into fresh air. If not breathing, give artificial respiration. Consult a physician.
In case of skin contact
Take off contaminated clothing and shoes immediately. Wash off with soap and plenty of water. Consult a
physician.
In case of eye contact
Rinse thoroughly with plenty of water for at least 15 minutes and consult a physician.
If swallowed
Do NOT induce vomiting. Never give anything by mouth to an unconscious person. Rinse mouth with
water. Consult a physician.
Most important symptoms and effects, both acute and delayed
The most important known symptoms and effects are described in the labelling (see section 2.2) and/or in
section 11
Indication of any immediate medical attention and special treatment needed
no data available

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SECTION 5: Firefighting measures
Extinguishing media
Suitable extinguishing media
Use water spray, alcohol-resistant foam, dry chemical or carbon dioxide.
Special hazards arising from the substance or mixture
Carbon oxides, nitrogen oxides (NOx)
Advice for firefighters
Wear self contained breathing apparatus for fire fighting if necessary.
Further information
no data available

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SECTION 6: Accidental release measures
Personal precautions, protective equipment and emergency procedures
Use personal protective equipment. Avoid breathing vapours, mist or gas. Ensure adequate ventilation.
Evacuate personnel to safe areas.
For personal protection see section 8.
Environmental precautions
Do not let product enter drains.
Methods and materials for containment and cleaning up
Soak up with inert absorbent material and dispose of as hazardous waste. Keep in suitable, closed
containers for disposal.
Reference to other sections
For disposal see section 13.

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SECTION 7: Handling and storage
Precautions for safe handling
Avoid inhalation of vapour or mist.
For precautions see section 2.2.
Conditions for safe storage, including any incompatibilities
Store in cool place. Keep container tightly closed in a dry and well-ventilated place. Containers which are
opened must be carefully resealed and kept upright to prevent leakage.
Store under inert gas. Sensitive to carbon dioxide
Specific end use(s)
A part from the uses mentioned in section 1.2 no other specific uses are stipulated

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SECTION 8: Exposure controls/personal protection
Control parameters
Components with workplace control parameters
Exposure controls
Appropriate engineering controls
Handle in accordance with good industrial hygiene and safety practice. Wash hands before breaks and
at the end of workday.
Personal protective equipment
Eye/face protection
Tightly fitting safety goggles. Faceshield (8-inch minimum). Use equipment for eye protection
tested and approved under appropriate government standards such as NIOSH (US) or EN
166(EU).
Skin protection
Handle with gloves. Gloves must be inspected prior to use. Use proper glove removal technique
(without touching glove's outer surface) to avoid skin contact with this product. Dispose of
contaminated gloves after use in accordance with applicable laws and good laboratory practices.
Wash and dry hands.
The selected protective gloves have to satisfy the specifications of EU Directive 89/686/EEC and
the standard EN 374 derived from it.
Full contact
Material: Nitrile rubber
Minimum layer thickness: 0,11 mm
Break through time: 480 min
Material tested:Dermatril® (KCL 740 / Z677272, Size M)
Splash contact
Material: Nitrile rubber
Minimum layer thickness: 0,11 mm
Break through time: 480 min
Material tested:Dermatril® (KCL 740 / Z677272, Size M)
data source: KCL GmbH, D-36124 Eichenzell, phone [phone], test method: EN374
If used in solution, or mixed with other substances, and under conditions which differ from EN 374,
contact the supplier of the CE approved gloves. This recommendation is advisory only and must
be evaluated by an industrial hygienist and safety officer familiar with the specific situation of
anticipated use by our customers. It should not be construed as offering an approval for any
specific use scenario.
Body Protection
Complete suit protecting against chemicals, The type of protective equipment must be selected
according to the concentration and amount of the dangerous substance at the specific workplace.
Respiratory protection
Where risk assessment shows air-purifying respirators are appropriate use a full-face respirator
with multi-purpose combination (US) or type ABEK (EN 14387) respirator cartridges as a backup
to engineering controls. If the respirator is the sole means of protection, use a full-face supplied air
respirator. Use respirators and components tested and approved under appropriate government
standards such as NIOSH (US) or CEN (EU).
Control of environmental exposure
Do not let product enter drains.

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SECTION 9: Physical and chemical properties
Information on basic physical and chemical properties
a) Appearance Form: clear, liquid
Colour: colourless
b) Odour no data available
c) Odour Threshold no data available
d) pH no data available
e) Melting point/freezing no data available
point
f) Initial boiling point and no data available
boiling range
g) Flash point no data available
h) Evapouration rate no data available
i) Flammability (solid, gas) no data available
j) Upper/lower no data available
flammability or
explosive limits
k) Vapour pressure no data available
l) Vapour density no data available
m) Relative density 1,010 g/cm3
n) Water solubility no data available
o) Partition coefficient: n- no data available
octanol/water
p) Auto-ignition no data available
temperature
q) Decomposition no data available
temperature
r) Viscosity no data available
s) Explosive properties no data available
t) Oxidizing properties no data available
Other safety information
no data available

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SECTION 10: Stability and reactivity
Reactivity
no data available
Chemical stability
Stable under recommended storage conditions.
Possibility of hazardous reactions
no data available
Conditions to avoid
no data available
Incompatible materials
Strong oxidizing agents
Hazardous decomposition products
Other decomposition products - no data available
In the event of fire: see section 5

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SECTION 11: Toxicological information
Information on toxicological effects
Acute toxicity
no data available
Skin corrosion/irritation
no data available
Serious eye damage/eye irritation
no data available
Respiratory or skin sensitisation
no data available
Germ cell mutagenicity
no data available
Carcinogenicity
IARC: No component of this product present at levels greater than or equal to 0.1% is identified as
probable, possible or confirmed human carcinogen by IARC.
Reproductive toxicity
no data available
Specific target organ toxicity - single exposure
no data available
Specific target organ toxicity - repeated exposure
no data available
Aspiration hazard
no data available
Additional Information
RTECS: Not available
Material is extremely destructive to tissue of the mucous membranes and upper respiratory tract, eyes, and
skin., spasm, inflammation and edema of the larynx, spasm, inflammation and edema of the bronchi,
pneumonitis, pulmonary edema, burning sensation, Cough, wheezing, laryngitis, Shortness of breath,
Headache, Nausea

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SECTION 12: Ecological information
Toxicity
no data available
Persistence and degradability
no data available
Bioaccumulative potential
no data available
Mobility in soil
no data available
Results of PBT and vPvB assessment
PBT/vPvB assessment not available as chemical safety assessment not required/not conducted
Other adverse effects
no data available

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SECTION 13: Disposal considerations
Waste treatment methods
Product
Offer surplus and non-recyclable solutions to a licensed disposal company.
Contaminated packaging
Dispose of as unused product.

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SECTION 14: Transport information
UN number
ADR/RID: 3267 IMDG: 3267 IATA: 3267
UN proper shipping name
ADR/RID: CORROSIVE LIQUID, BASIC, ORGANIC, N.O.S. (Ethanaminium, N-ethyl-N,N-dimethyl-,
hydroxide (1:1))
IMDG: CORROSIVE LIQUID, BASIC, ORGANIC, N.O.S. (Ethanaminium, N-ethyl-N,N-dimethyl-,
hydroxide (1:1))
IATA: Corrosive liquid, basic, organic, n.o.s. (Ethanaminium, N-ethyl-N,N-dimethyl-, hydroxide (1:1))
Transport hazard class(es)
ADR/RID: 8 IMDG: 8 IATA: 8
Packaging group
ADR/RID: II IMDG: II IATA: II
Environmental hazards
ADR/RID: no IMDG Marine pollutant: no IATA: no
Special precautions for user
no data available

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SECTION 15 - REGULATORY INFORMATION
N/A

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SECTION 16 - ADDITIONAL INFORMATION
N/A

反应信息

• 作为反应物：
  描述：

  二乙基二甲基氢氧化铵 生成 二甲基十二/十四烷基叔胺 、 乙烯
  参考文献：
  名称：

  Collie; Schryver, Journal of the Chemical Society, 1890, vol. 57, p. 774

  摘要：

  DOI：

文献信息

• [EN] INDOLYL PYRAZINONE DERIVATIVES USEFUL FOR TREATING HYPER-PROLIFERATIVE DISORDERS AND DISEASES ASSOCIATED WITH ANGIOGENESIS<br/>[FR] DERIVES D'INDOLYLE PYRAZINONE UTILES POUR LE TRAITEMENT DES MALADIES ET DES TROUBLES HYPERPROLIFERANTS ASSOCIES A L'ANGIOGENESE
  申请人：BAYER PHARMACEUTICALS CORP

  公开号：WO2004043950A1

  公开（公告）日：2004-05-27

  This invention relates to a compound of Formula I (I)and its use in treating hyper-proliferative disorders and diseases associated with angiogenesis.

  这项发明涉及一种式I（I）化合物及其在治疗与血管生成有关的高增殖性疾病和疾病中的应用。
• NOVEL NITRILE AND AMIDOXIME COMPOUNDS AND METHODS OF PREPARATION
  申请人：Lee Wai Mun

  公开号：US20090111965A1

  公开（公告）日：2009-04-30

  The present application relates to semiconductor processing compositions comprising at least one compound containing at least one amidoxime functional group and to methods of using these compositions in semiconductor processing. The present application also describes the preparation of amidoximes for a semiconductor processing composition by (a) mixing a cyanoethylation catalyst, a nucleophile and an alpha-unsaturated nitrile to produce a cyanoethylation product; and (b) converting a cyano group in the cyanoethylation product into an amidoxime functional group.

  本申请涉及包含至少一个含有至少一个酰胺肟功能团的化合物的半导体加工组合物，以及使用这些组合物进行半导体加工的方法。本申请还描述了通过(a)混合氰乙基化催化剂、亲核试剂和不饱和α腈以产生氰乙基化产品；(b)将氰乙基化产品中的氰基团转化为酰胺肟功能团来制备用于半导体加工组合物的酰胺肟的方法。
• Method of preparing a purified ester-substituted phenol stream
  申请人：Belfadhel Hatem

  公开号：US20090143610A1

  公开（公告）日：2009-06-04

  A method of producing a purified ester-substituted phenol stream is provided. The method includes a first step of obtaining from a melt transesterification reaction a byproduct stream containing a residual ester-substituted diaryl carbonate, an ester-substituted phenol, a residual melt transesterification catalyst, and a catalyst degradation product. A second step includes treating the reaction byproduct stream to separate ester-substituted phenol and catalyst degradation product from residual ester-substituted diaryl carbonate and residual melt transesterification catalyst to create a light recycle stream containing ester-substituted phenol and catalyst degradation product and a heavy recycle stream containing residual ester-substituted diaryl carbonate and residual melt transesterification catalyst. A third step includes treating the light recycle stream to reduce catalyst degradation product concentration thereby producing a purified ester-substituted phenol stream.

  提供了一种生产纯化酯基取代酚流的方法。该方法包括以下步骤：第一步，从熔融酯交酯化反应中获得一个副产物流，其中包含残留的酯基取代二芳基碳酸酯、酯基取代酚、残留的熔融酯交酯化催化剂和催化剂降解产物。第二步包括处理反应副产物流，以将酯基取代酚和催化剂降解产物与残留的酯基取代二芳基碳酸酯和残留的熔融酯交酯化催化剂分离，从而产生一个轻质回收流，其中包含酯基取代酚和催化剂降解产物，以及一个重质回收流，其中包含残留的酯基取代二芳基碳酸酯和残留的熔融酯交酯化催化剂。第三步包括处理轻质回收流，以减少催化剂降解产物浓度，从而生产纯化的酯基取代酚流。
• Articles Comprising Benzopyran Colorants, Method Of Manufacture, And Method Of Use
  申请人：Chauhan B. Yogendrasinh

  公开号：US20070238817A1

  公开（公告）日：2007-10-11

  An article comprising the compound of Formula (I) wherein X is hydrogen or a radical of Formula (II), R 1 independently at each occurrence is a C 1 -C 20 aliphatic radical, a C 3 -C 10 cycloaliphatic radical, or a C 3 -C 10 aromatic radical; R 2 , R 3 , R 4 and R 5 are independently at each occurrence a halogen, a nitro group, a cyano group, a hydroxy group, a C 1 -C 20 aliphatic radical, a C 3 -C 20 cycloaliphatic radical, or a C 6 -C 20 aromatic radical; and “n”, “q”, and “p” are each independently integers having a value of 0 to 3, and “m” is an integer having a value of 0 to 4.

  一篇包括化合物Formula (I)的文章，其中X是氢或Formula (II)的基团，R1在每次出现时独立地是C1-C20脂肪基、C3-C10环脂基或C3-C10芳香基；R2、R3、R4和R5在每次出现时独立地是卤素、硝基、氰基、羟基、C1-C20脂肪基、C3-C20环脂基或C6-C20芳香基；而“n”、“q”和“p”分别是独立的整数，取值范围为0到3，“m”是一个整数，取值范围为0到4。
• Uranyl–Organic Hybrids Designed from Hydroxyphosphonate
  作者：Pius O. Adelani、Nicholas A. Martinez、Nathaniel D. Cook、Peter C. Burns

  DOI：10.1002/ejic.201402764

  日期：2015.1

  based on the reaction of uranyl cations with 2,5-dihydroxy-1,4-benzenediphosphonic acid in the presence of a variety of alkali metal and organoammonium cations: K[(UO2)2F2H0.5O3PC6H2(OH)2PO3H0.5}](H2O)2 (1), Cs[(UO2)2H0.75O3PC6H2(OH)2PO3H0.75}](H2O)4·2H2O (2), [(CH3)4N]2[UO2HO3PC6H2(OH)2PO3H}2] (3), [(CH3CH2)4N][UO2FHO3PC6H2(OH)2PO3H}] (4), and [(CH3CH2)2N(CH3)2][UO2FHO3PC6H2(OH)2PO3H}] (5). In

  基于铀酰阳离子与 2​​,5-二羟基-1,4-苯二膦酸在多种碱金属和有机铵阳离子存在下的反应，组装了一系列基于膦酸酯的铀酰-有机杂化物：K[(UO2 )2F2H0.5O3PC6H2(OH)2PO3H0.5}](H2O)2 (1), Cs[(UO2)2H0.75O3PC6H2(OH)2PO3H0.75}](H2O)4·2H2O (2), [(CH3)4N]2[UO2HO3PC6H2(OH)2PO3H}2](3)、[(CH3CH2)4N][UO2FHO3PC6H2(OH)2PO3H}](4)和[(CH3CH2)2N(CH3) )2][UO2FHO3PC6H2(OH)2PO3H}] (5)。在化合物1、4和5中，UO5F2五角双锥的链通过羟基膦酸酯部分连接成三维骨架，化合物4与5同构。而2和3的结构由单体UO7五角双锥组装而成形成层状结构单元。