5-(2-chlorophenyl)-N-methylfuran-2-carboxamide

• 分子结构分类: 有机化合物 - 有机酸及其衍生物 - 羧酸及其衍生物
• 英文名称: 5-(2-chlorophenyl)-N-methylfuran-2-carboxamide
• 化学式: C₁₂H₁₀ClNO₂
• 分子量: 235.66
• InChiKey: ACPOPTAXYAKJMG-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  2.9
• 重原子数：
  16
• 可旋转键数：
  2
• 环数：
  2.0
• sp3杂化的碳原子比例：
  0.08
• 拓扑面积：
  42.2
• 氢给体数：
  1
• 氢受体数：
  2

文献信息

• Methods of Treating an Overweight or Obese Subject
  申请人：Vath James E.

  公开号：US20120010259A1

  公开（公告）日：2012-01-12

  The invention herein generally relates to methods of treating a subject having an overweight or obese condition, and overweight- or obesity-related conditions. In one embodiment, the invention herein provides a method of treating a subject having an overweight or obese condition involving administering to the subject in need thereof, an amount of a pharmaceutical composition including a MetAP-2 inhibitory compound, or a salt, ester, or prodrug thereof, effective to result in weight loss in the subject.