过氧化二硬脂酸 | 3273-75-4

• 分子结构分类: 有机化合物 - 有机酸及其衍生物 - 羧酸及其衍生物
• 中文名称: 过氧化二硬脂酸
• 英文名称: Distearoyl-peroxid
• 英文别名: Stearoyl peroxide；octadecanoyl octadecaneperoxoate
• CAS: 3273-75-4
• 化学式: C₃₆H₇₀O₄
• 分子量: 566.949
• InChiKey: XNTUJOTWIMFEQS-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  17
• 重原子数：
  40
• 可旋转键数：
  35
• 环数：
  0.0
• sp3杂化的碳原子比例：
  0.94
• 拓扑面积：
  52.6
• 氢给体数：
  0
• 氢受体数：
  4

安全信息

• 海关编码：
  2915900090

反应信息

• 作为反应物：
  描述：

  过氧化二硬脂酸 、 甲萘醌 在 Petroleum ether 作用下， 生成 2-heptadecyl-3-methyl-[1,4]naphthoquinone
  参考文献：
  名称：

  Fieser; Oxford, Journal of the American Chemical Society, 1942, vol. 64, p. 2063

  摘要：

  DOI：
• 作为产物：
  描述：

  十八烷酰氯 在 sodium hydroxide 、 双氧水 作用下， 以 乙醚 为溶剂， 反应 0.2h， 生成 过氧化二硬脂酸
  参考文献：
  名称：

  Alkyl Monolayers on Silicon Prepared from 1-Alkenes and Hydrogen-Terminated Silicon

  摘要：

  High-quality alkyl monolayers on silicon have been prepared from 1-alkenes and hydrogen-terminated Si(111). The 1-alkenes form monolayers upon free-radical initiation with diacylperoxides. Heat also initiates monolayer formation, although monolayers prepared from heated long-chain l-alkenes are of lower quality than those prepared with free-radical initiation. Even when a high concentration of diacyl peroxide is used to initiate monolayer formation, the l-alkene is the primary constituent of the monolayer. Alkynes also form monolayers on silicon when initiated by diacyl-peroxides, X-ray reflectivity shows that the monolayer thickness is of molecular dimensions and that the density is close to that of crystalline hydrocarbons (similar to 90%). Infrared spectroscopy shows that the alkyl chains in the monolayers are densely packed. Infrared dichroism shows that the chains are tilted from the surface normal and twisted about their axes. The wetting properties of the monolayers show that they are methyl terminated. After many weeks of air exposure, the silicon substrate under the monolayers is not significantly oxidized. The monolayers are very stable to boiling chloroform, boiling water, boiling acidic and basic solutions, and fluoride and are at least as stable as similar chain-length monolayers prepared from trichlorosilanes on oxidized silicon. We propose that alkyl chains in the monolayers are bound to the silicon substrate through silicon-carbon bonds and compare a proposed mechanism of bond formation to analogous homogeneous reactions.

  DOI：

  10.1021/ja00116a019

文献信息

• ASYMMETRIC ORGANIC PEROXIDE, CROSSLINKING AGENT COMPRISING THE SAME, AND METHOD OF CROSSLINKING WITH THE SAME
  申请人：NOF CORPORATION

  公开号：EP1233014A1

  公开（公告）日：2002-08-21

  A crosslinking agent comprising an asymmetry organic peroxide having at least one structure unit of (substituted)benzoylcarbonyloxy group represented by the following formula (1) in the molecule thereof. Environmentally friendly crosslinking agents and crosslinked silicone rubber moldings are provided thereby. Specifically, useful crosslinking agents and crosslinking processes for silicone rubber are provided.

  一种交联剂，包括至少具有分子中表示为以下式（1）的（取代）苯甲酰羰氧基结构单元的不对称有机过氧化物。因此提供了环保的交联剂和交联硅橡胶成型品。具体提供了用于硅橡胶的有用交联剂和交联工艺。
• Siosomal formulation for intracellular delivery and targeting of therapeutic agents
  申请人：Salama, Zoser B.

  公开号：EP2384743A1

  公开（公告）日：2011-11-09

  The invention relates to a carrier and targeting system for the intracellular delivery and triggered release of a siosome- and/or siosome-liposome-entrapped or encapsulated active substance or therapeutic agent. The invention further relates to the targeted release and delivery of doxorubicin, cis-platin, carbo-platin and/or oxali-platin, characterized in that one or more anionic lipids, such as cholesteryl hemisuccinate residues, cardiolipin and/or their derivatives and/or other anionic groups, are covalently linked to the silicone central atom of the silanes, sugar silanes and/or amino-sugar silanes. The invention further relates to the use of cationic lipids that are covalently attached to the silicone central atom of the silanes. The invention also relates to a method for preparing such carrier and targeting systems and methods for their administration.

  该发明涉及一种用于细胞内递送和触发释放siosome和/或siosome-脂质体包埋或封装活性物质或治疗剂的载体和靶向系统。该发明还涉及对阿霉素、顺铂、卡铂和/或奥沙利铂的靶向释放和递送，其特征在于将一个或多个阴离子脂质，如胆固醇半琥珀酸酯残基、心磷脂和/或它们的衍生物和/或其他阴离子基团，共价连接到硅烷、糖硅烷和/或氨基糖硅烷的硅中心原子上。该发明还涉及将阳离子脂质共价连接到硅烷的中心原子的使用。该发明还涉及一种制备这种载体和靶向系统的方法以及它们的给药方法。
• [EN] OXYGEN PERMEABLE HYDROUS CONTACT LENS AND COMPOSITION THEREFOR<br/>[FR] LENTILLE DE CONTACT HYDRATÉE PERMÉABLE À L'OXYGÈNE ET COMPOSITION ASSOCIÉE
  申请人：SEED CO LTD

  公开号：WO2014123959A1

  公开（公告）日：2014-08-14

  The present invention relates to a composition and an oxygen permeable hydrous contact lens made therefrom. More particularly, the present invention relates to a composition for an oxygen permeable hydrous contact lens comprising a monomer intramolecularly having silicon-containing moieties, at least one hydrophilic group, a cyclic hydrocarbon group, and an acryloyloxy or methacryloyloxy group; a hydrophilic monomer; and a second silicon-containing monomer, as well as to an oxygen permeable hydrous contact lens obtained from the composition.

  本发明涉及一种组合物和由此制成的透氧性水合接触镜。更具体地，本发明涉及一种用于透氧性水合接触镜的组合物，包括具有含硅基团的单体、至少一个亲水基团、一个环烃基团和一个丙烯酰氧基或甲基丙烯酰氧基的单体；一个亲水单体；和第二个含硅单体，以及由该组合物获得的透氧性水合接触镜。
• DIENE-BASED CARBOXYLATE ANION AND SALT THEREOF, AND POLYMERIZABLE OR CURABLE COMPOSITION THEREOF
  申请人：Kaneko Tomomasa

  公开号：US20130197123A1

  公开（公告）日：2013-08-01

  The claimed invention provides a novel compound not having been studied before, that is, a diene carboxylate anion that contains a specific structure, and a salt thereof. The claimed invention further provides a diene carboxylate anion and a salt thereof, especially a metal salt thereof, which are easily soluble in general organic solvents, reactive diluents, and resins, may be in a liquid state at normal temperature depending on the structure, and have high polymerizability. Polymerization/curing of these produces a resin to which many ionic bonds and a metal are introduced, providing various properties such as hardness, scratch resistance, anti-fingerprint property, gas-barrier property, water vapor barrier property, oxygen absorption property, ultraviolet protection, infrared protection, color development and coloring, high refractive index, adhesion, various catalytic abilities, fluorescence ability and light-emitting ability, optical amplification, dispersibility, and antistatic properties. In addition, the anion and the salt can be used for raw materials for functional fine particles and for metal nanoparticle composites, and also for MOD materials. The claimed invention also provides an advantageous method for producing the diene carboxylate anion and the salt thereof.

  所述发明提供了一种新颖的化合物，此化合物以前未被研究过，即一种含有特定结构的二烯二酸盐阴离子及其盐。所述发明进一步提供了一种二烯二酸盐阴离子及其盐，特别是其金属盐，这些盐在一般有机溶剂、反应性稀释剂和树脂中易溶解，在常温下可能处于液态，具有高聚合性。这些的聚合/固化产生的树脂引入了许多离子键和金属，提供了硬度、抗刮擦性、防指纹性、气体屏障性、阻水汽性、氧气吸收性、紫外线保护、红外线保护、颜色开发和着色、高折射率、粘附性、各种催化能力、荧光能力和发光能力、光学放大、分散性和抗静电性等各种性能。此外，该阴离子和盐可用作功能性细颗粒和金属纳米粒子复合材料的原材料，也可用于MOD材料。所述发明还提供了一种生产二烯二酸盐阴离子及其盐的优势方法。
• Decarboxylative C(sp³)–N Cross-Coupling of Diacyl Peroxides with Nitrogen Nucleophiles
  作者：Zi-Liang Tang、Xuan-Hui Ouyang、Ren-Jie Song、Jin-Heng Li

  DOI：10.1021/acs.orglett.0c04203

  日期：2021.2.5

  We have disclosed a new radical-mediated decarboxylative C(sp3)–N cross-coupling of diacyl peroxides with nitrogen nucleophiles. The primary and secondary alkyl radicals derived from corresponding diacyl peroxides were generated by copper catalysis or by merging copper catalysis and photoredox catalysis, respectively. Various N-alkyl nitrogen nucleophiles, including indazoles, triazoles, indoles, purine

  我们已经公开了一种新的自由基介导的脱羧 C(sp 3 )-N 交叉偶联二酰基过氧化物与氮亲核试剂。由相应的二酰基过氧化物衍生的伯和仲烷基分别通过铜催化或合并铜催化和光氧化还原催化产生。各种N-烷基氮亲核试剂，包括吲唑、三唑、吲哚、嘌呤、咔唑、苯胺和磺酰胺，具有广泛的底物范围和良好的官能团耐受性。