摩熵化学
数据库官网
小程序
打开微信扫一扫
首页 分子通 化学资讯 化学百科 反应查询 关于我们
请输入关键词

二十二碳六烯酸 | 32839-18-2

中文名称
二十二碳六烯酸
中文别名
——
英文名称
docosahexenoic acid
英文别名
DHA;docosahexaenoic acid;Docosahexaenoic acid, (Z,Z,Z,Z,Z,Z)-;(2Z,4Z,6Z,8Z,10Z,12Z)-docosa-2,4,6,8,10,12-hexaenoic acid
二十二碳六烯酸化学式
CAS
32839-18-2
化学式
C22H32O2
mdl
——
分子量
328.495
InChiKey
DVSZKTAMJJTWFG-NMAMXRDHSA-N
BEILSTEIN
——
EINECS
——
  • 物化性质
  • 计算性质
  • ADMET
  • 安全信息
  • SDS
  • 制备方法与用途
  • 上下游信息
  • 反应信息
  • 文献信息
  • 表征谱图
  • 同类化合物
  • 相关功能分类
  • 相关结构分类

计算性质

  • 辛醇/水分配系数(LogP):
    8.1
  • 重原子数:
    24
  • 可旋转键数:
    14
  • 环数:
    0.0
  • sp3杂化的碳原子比例:
    0.41
  • 拓扑面积:
    37.3
  • 氢给体数:
    1
  • 氢受体数:
    2

安全信息

  • 海关编码:
    2106909090

SDS

SDS:db1e7034e93751f4b19792b5fbed78dd
查看

反应信息

点击查看最新优质反应信息

文献信息

  • [EN] LIPID COMPOSITIONS CONTAINING DERIVATIVES OF EPA AND DHA AN THEIR USE THEREOF<br/>[FR] COMPOSITIONS LIPIDIQUES RENFERMANT DES DÉRIVÉS D'EPA ET DE DHA ET LEUR UTILISATION
    申请人:PRONOVA BIOPHARMA NORGE AS
    公开号:WO2009134147A1
    公开(公告)日:2009-11-05
    The present invention relates to a lipid composition comprising at least pro-drugs of omega-3 polyunsaturated alcohols, which pro-drugs of omega-3 polyunsaturated alcohols comprise at least one pro-drug of (all-Z) 5,8,11,14,17-eicosapentaen-1-ol, and at least one pro-drug of (all-Z)-4,7,10,13,16,19-docosahexaen-1-ol and their use as a pharmaceutical, in particular for the treatment of elevated triglyceride levels. The invention also relates to methods for the preparation of these pro-drugs from marine oils.
    本发明涉及一种脂质组合物,其中至少包括ω-3多不饱和醇的前药,这些ω-3多不饱和醇的前药至少包括(全反式)5,8,11,14,17-二十碳五烯醇的前药和(全反式)4,7,10,13,16,19-二十二碳六烯醇的前药,以及它们在制药学中的应用,特别是用于治疗高三酰甘油血症。本发明还涉及从海洋油中制备这些前药的方法。
  • FATTY ACID ALCOHOLS
    申请人:Holmeide Anne Kristin
    公开号:US20100266681A1
    公开(公告)日:2010-10-21
    The present invention relates to a lipid composition comprising at least omega-3 polyunsaturated alcohols, or pro-drugs thereof, which omega-3 polyunsaturated alcohols, or pro-drugs thereof, comprising at least (all-Z)-5,8,11,14,17-eicosapentaen-1-ol, or pro-drug thereof, and (all-Z)-4,7,10,13,16,19-docosahexaen-1-ol, or pro-drug thereof, and their use as a pharmaceutical, in particular for the treatment of elevated triglyceride levels. The invention also relates to methods for the preparation of these pro-drugs from marine oils.
  • [EN] FATTY ACID ALCOHOLS<br/>[FR] ALCOOLS D'ACIDES GRAS
    申请人:PRONOVA BIOPHARMA NORGE AS
    公开号:WO2008139261A2
    公开(公告)日:2008-11-20
    (EN) The present invention relates to a lipid composition comprising at least omega-3 polyunsaturated alcohols, or pro-drugs thereof, which omega-3 polyunsaturated alcohols, or pro-drugs thereof, comprising at least (all-Z)-5,8,11,14,17-eicosapentaen- 1-ol, or pro-drug thereof, and (all-Z)-4,7,10,13,16,19-docosahexaen-1-ol, or pro-drug thereof, and their use as a pharmaceutical, in particular for the treatment of elevated triglyceride levels. The invention also relates to methods for the preparation of these pro-drugs from marine oils.(FR) La présente invention porte sur une composition lipidique comprenant au moins des alcools polyinsaturés oméga-3, ou des pro-médicaments de ceux-ci, lesquels alcools polyinsaturés oméga-3 ou pro-médicaments de ceux-ci comprennent au moins le (tout-Z)-5,8,11,14,17-eicosapentaène-1-ol, ou un pro-médicament de celui-ci, et le (tout-Z)-4,7,10,13,16,19-docosahexaène-1-ol, ou un pro-médicament de celui-ci, et sur leur utilisation comme produits pharmaceutiques, en particulier pour le traitement de taux élevés de triglycérides. L'invention porte également sur des procédés pour la préparation de ces pro-médicaments à partir d'huiles marines.
查看更多