5-chloro-2-nonyl-1H-benzo[d]imidazole

• 分子结构分类: 有机化合物 - 有机杂环化合物 - 苯并咪唑类
• 英文名称: 5-chloro-2-nonyl-1H-benzo[d]imidazole
• 英文别名: 6-chloro-2-nonyl-1H-benzimidazole
• 化学式: C₁₆H₂₃ClN₂
• 分子量: 278.825
• InChiKey: MBHHSNNDTYJFQL-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  6.3
• 重原子数：
  19
• 可旋转键数：
  8
• 环数：
  2.0
• sp3杂化的碳原子比例：
  0.56
• 拓扑面积：
  28.7
• 氢给体数：
  1
• 氢受体数：
  1

反应信息

• 作为产物：
  描述：

  正癸酸 、 4-氯-1,2-苯二胺 以 neat (no solvent) 为溶剂， 反应 1.0h， 以64%的产率得到5-chloro-2-nonyl-1H-benzo[d]imidazole
  参考文献：
  名称：

  具有烷基、环烷基或吡啶部分的新型苯并唑的合成和抑瘤活性评价

  摘要：

  具有苯并咪唑系统的化合物表现出显着的抗结核活性。为了研究结构修饰如何影响抗结核活性，合成了一系列苯并唑衍生物并筛选了它们的抗结核活性。通过邻二胺、邻氨基苯酚或邻氨基苯硫酚与羧酸或硫代酰胺反应得到化合物1-20。新合成的化合物通过IR、1H-NMR、13C-NMR光谱和元素分析进行​​表征。评价合成的苯并唑对结核分枝杆菌菌株的抑结核活性。使用 Gaussian 03W 软件（Gaussian, Inc., Wallingford, CT, 美国）。苯并咪唑 1⁻3、MC-9 和 GK-151B 的三维结构通过使用 Gamess-US 软件从头计算确定。收到的苯并咪唑的活性中等或良好。所有苯并恶唑和苯并噻唑都表现出低得多的活性。苯并恶唑的活性比苯并咪唑类似物低约 50 倍，而苯并噻唑的活性低 100 倍。量子化学计算表明苯并咪唑和苯并恶唑的苯并唑体系中静电势的分布存在差异。三维结构计算揭示了 C2

  DOI：

  10.3390/molecules23040985

文献信息

• ELECTRODE CONNECTION METHOD, ELECTRODE CONNECTION STRUCTURE, CONDUCTIVE ADHESIVE USED THEREFOR, AND ELECTRONIC DEVICE
  申请人：Sumitomo Electric Industries, Ltd.

  公开号：EP2445323A1

  公开（公告）日：2012-04-25

  By connecting together connecting electrodes having an organic film serving as an oxidation-preventing film using a conductive adhesive, the manufacturing process can be simplified, and a highly reliable connection structure can be constructed at low cost. An electrode connection method, in which a first connecting electrode 2 and a second connecting electrode 10 are connected together through a conductive adhesive 9 that is interposed between the electrodes, includes an organic film formation step in which an organic film 6 is formed on at least a surface of the first connecting electrode, and an electrode connection step in which the first connecting electrode and the second connecting electrode are connected together through the conductive adhesive. In the electrode connection step, by allowing an organic film decomposing component mixed in the conductive adhesive to act on the organic film, the organic film is decomposed, and thus connection between the connecting electrodes is performed.

  通过使用导电粘合剂将具有作为氧化防止膜的有机薄膜的连接电极连接在一起，可以简化制造过程，并以低成本构建高可靠性的连接结构。第一连接电极 2 和第二连接电极 10 通过电极之间的导电粘合剂 9 连接在一起的电极连接方法，包括在第一连接电极的至少一个表面上形成有机薄膜 6 的有机薄膜形成步骤，以及通过导电粘合剂将第一连接电极和第二连接电极连接在一起的电极连接步骤。在电极连接步骤中，通过让混在导电胶中的有机膜分解成分作用于有机膜，有机膜被分解，从而实现连接电极之间的连接。
• ELECTRODE CONNECTION STRUCTURE, CONDUCTIVE ADHESIVE USED THEREFOR, AND ELECTRONIC DEVICE
  申请人：Yamamoto Masamichi

  公开号：US20110250395A1

  公开（公告）日：2011-10-13

  There is provided a connecting structure with high reliability produced at low cost through the production process simplified by connecting connection electrodes, each including an organic film as an oxidation preventing film, to each other using a conductive adhesive. An electrode-connecting structure in which a first connection electrode 2 and a second connection electrode 10 are connected to each other with a conductive adhesive layer 9 therebetween includes organic films 6 and 11 formed on at least the first connection electrode and conductive particles 8 contained so that major axes of the particles are oriented in a thickness direction of the conductive adhesive layer and the average length of the major axes is larger than the total thickness of at least the organic films and the conductive adhesive layer, wherein the conductive particles pierce the organic films and contact the first connection electrode and the second connection electrode.
• US9226406B2
  申请人：——

  公开号：US9226406B2

  公开（公告）日：2015-12-29