tert-butyl 3-amino-3-(4-trifluoromethyl-3-pyridinecarbonyloxy-imino)propionate

• 分子结构分类: 有机化合物 - 有机杂环化合物 - 吡啶及其衍生物
• 英文名称: tert-butyl 3-amino-3-(4-trifluoromethyl-3-pyridinecarbonyloxy-imino)propionate
• 英文别名: [(E)-[1-amino-3-[(2-methylpropan-2-yl)oxy]-3-oxopropylidene]amino] 4-(trifluoromethyl)pyridine-3-carboxylate
• 化学式: C₁₄H₁₆F₃N₃O₄
• 分子量: 347.294
• InChiKey: IRHMMXIWTDHTIO-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  2
• 重原子数：
  24
• 可旋转键数：
  7
• 环数：
  1.0
• sp3杂化的碳原子比例：
  0.43
• 拓扑面积：
  104
• 氢给体数：
  1
• 氢受体数：
  9

反应信息

• 作为反应物：
  描述：

  tert-butyl 3-amino-3-(4-trifluoromethyl-3-pyridinecarbonyloxy-imino)propionate 在 silica gel 作用下， 以 甲苯 为溶剂， 反应 17.0h， 以gives 14.4 g of the product as a pale brown oil的产率得到3-(tert-butoxycarbonylmethyl)-5-(4-trifluoromethyl-3-pyridyl)-1,2,4-oxadiazole
  参考文献：
  名称：

  4-haloalkyl-3-heterocyclylpyridines, 4-haloalkyl-5-heterocyclyl-pyrimidines and 4-trifluoromethyl-3-oxadiazolylpyridines, processes for their preparation, compositions comprising them, and their use as pesticides

  摘要：

  本发明涉及4-卤代烷基-3-杂环基吡啶、4-卤代烷基-5-杂环基嘧啶和4-三氟甲基-3-噁唑基吡啶的制备方法，包含它们的组合物以及它们作为杀虫剂的用途。特别地，本发明涉及式(I')的4-三氟甲基-3-噁唑基吡啶，它们的制备方法，包含它们的组合物以及这些化合物用于控制动物害虫，特别是昆虫、蜘蛛螨、外寄生虫和蠕虫的用途：1其中X、Y在说明中定义。

  公开号：

  US20030162812A1
• 作为产物：
  描述：

  4-三氟甲基烟酸 、 Carbonyldiimidazole 、 tert-butyl (E)-3-amino-3-(hydroxyimino)propanoate 在 硫酸 、 乙酸乙酯 作用下， 以 四氢呋喃 为溶剂， 反应 16.5h， 以Concentration of the ethyl acetate phase gives 28 g of the product as a pale yellow solid的产率得到tert-butyl 3-amino-3-(4-trifluoromethyl-3-pyridinecarbonyloxy-imino)propionate
  参考文献：
  名称：

  4-haloalkyl-3-heterocyclylpyridines and 4-haloalkyl-5-heterocyclylpyrimidines, processes for their preparation, compositions comprising them, and their use as pesticides

  摘要：

  本发明涉及式(I)的4-卤代烷基-3-杂环基吡啶和4-卤代烷基-5-杂环基嘧啶，以及它们的制备方法、包含它们的组合物，以及这些化合物用于控制动物害虫，特别是昆虫、蜘蛛螨、寄生虫和蠕虫的用途。在式(I)中，Q是一个5-成员杂环基，可以被卤素或有机基团取代，Y是卤代C1-C8-烷基，X是CH或N，m为0或1。

  公开号：

  US06239160B1

文献信息

• 4-haloalkyl-3-heterocyclylpyridines and 4-haloalkyl-5-heterocyclylpyrimidines, processes for their preparation, compositions comprising them, and their use as pesticides
  申请人：Hoechst Schering AgrEvo GmbH

  公开号：US06239160B1

  公开（公告）日：2001-05-29

  The present invention relates to 4-haloalkyl-3-heterocyclylpyridines and 4-haloalkyl-5-heterocyclylpyrimidines of the formula (I), to processes for their preparation, to compositions comprising them, and to the use of these compounds for controlling animal pests, in particular insects, spider mites, ectoparasites and helminths. In the formula (I), Q is a 5-membered heterocyclic group which is optionally substituted by halogen or organic radicals, Y is halo-C1-C8-alkyl, X is CH or N and m is 0 or 1.

  本发明涉及式(I)的4-卤代烷基-3-杂环基吡啶和4-卤代烷基-5-杂环基嘧啶，以及它们的制备方法、包含它们的组合物，以及利用这些化合物来控制动物害虫，特别是昆虫、蜘蛛螨、外寄生虫和蠕虫。在式(I)中，Q是一个5-成员杂环基，可选择地被卤素或有机基取代，Y是卤代C1-C8-烷基，X是CH或N，m为0或1。
• 4-haloalkyl-3-heterocyclylpyridines, 4-haloalkyl-5-heterocyclyl-pyrimidines and 4-trifluoromethyl-3-oxadiazolylpyridines, processes for their preparation, compositions comprising them, and their use as pesticides
  申请人：——

  公开号：US20030162812A1

  公开（公告）日：2003-08-28

  The present invention relates to 4-Haloalkyl-3-heterocyclylpyridines, 4-haloalkyl-5-heterocyclyl-pyrimidines and 4-trifluoromethyl-3-oxadiazolylpyridines, Processes for Their Preparation, Compositions Comprising Them, and Their Use as Pesticides More particularly, the present invention relates to 4-trifluoromethyl-3-oxadiazolylpyridines of the formula (I′), to processes for their preparation, to compositions comprising them and to the use of these compounds for controlling animal pests, in particular insects, spider mites, ectoparasites and helminths: 1 wherein X, Y are as defined in the description.

  本发明涉及4-卤代烷基-3-杂环基吡啶、4-卤代烷基-5-杂环基嘧啶和4-三氟甲基-3-噁二唑基吡啶，以及它们的制备方法、包含它们的组合物和它们作为杀虫剂的用途。更具体地，本发明涉及式(I′)的4-三氟甲基-3-噁二唑基吡啶，其制备方法，包含它们的组合物以及这些化合物用于控制动物害虫，特别是昆虫、蜘蛛螨、外寄生虫和蠕虫的用途：其中X、Y如描述中所定义。
• 4-Haloalkyl-3-heterocyclylpyridines and 4-haloalkyl-5-heterocyclyl-pyrimidines, processes for their preparation, compositions comprising them, and their use as pesticides
  申请人：——

  公开号：US20020013326A1

  公开（公告）日：2002-01-31

  4-Haloalkyl-3-heterocyclylpyridines and 4-haloalkyl-5-heterocyclyl-pyrimidines, processes for their preparation, compositions comprising them, and their use as pesticides The present invention relates to 4-haloalkyl-3-heterocyclylpyridines and 4-haloalkyl-5-heterocyclylpyrimidines of the formula (I), to processes for their preparation, to compositions comprising them, and to the use of these compounds for controlling animal pests, in particular insects, spider mites, ectoparasites and helminths. 1 In the formula (I), Q is a 5-membered heterocyclic group which is optionally substituted by halogen or organic radicals, Y is halo-C 1 -C 6 -alkyl, X is CH or N and m is 0 or 1.

  本发明涉及式(I)的4-卤代烷基-3-杂环基吡啶和4-卤代烷基-5-杂环基嘧啶，以及它们的制备方法、包含它们的组合物，以及这些化合物作为农药控制动物害虫，特别是昆虫、蜘蛛螨、外寄生虫和寄生虫的用途。 式(I)中，Q是一个5元杂环基团，可选择地被卤素或有机基团取代，Y是卤代C1-C6-烷基，X是CH或N，m为0或1。
• US6239160B1
  申请人：——

  公开号：US6239160B1

  公开（公告）日：2001-05-29
• US6521610B2
  申请人：——

  公开号：US6521610B2

  公开（公告）日：2003-02-18