diethyl (1,3-diacetylimidazolidine-4,5-diyl)dicarbamate

• 分子结构分类: 有机化合物 - 有机杂环化合物 - 唑烷类
• 英文名称: diethyl (1,3-diacetylimidazolidine-4,5-diyl)dicarbamate
• 英文别名: 1,3-Diacetyl-4,5-bis(ethoxycarbonylamino)imidazolidine；ethyl N-[1,3-diacetyl-5-(ethoxycarbonylamino)imidazolidin-4-yl]carbamate
• 化学式: C₁₃H₂₂N₄O₆
• 分子量: 330.341
• InChiKey: GAQJKLXBQZVZST-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  0.7
• 重原子数：
  23
• 可旋转键数：
  6
• 环数：
  1.0
• sp3杂化的碳原子比例：
  0.69
• 拓扑面积：
  117
• 氢给体数：
  2
• 氢受体数：
  6

反应信息

• 作为产物：
  描述：

  氨基甲酸乙酯 、 1,3-diacetylimidazolidine-4,5-diyl diacetate 在 对甲苯磺酸 作用下， 反应 0.5h， 以73%的产率得到diethyl (1,3-diacetylimidazolidine-4,5-diyl)dicarbamate
  参考文献：
  名称：

  Derivatives of 1,1,2,2-tetraaminoethane: II. Condensation of 4,5-diacetoxy-1,3-diacetylimidazolidine and 2,3-diacetoxy-1,4-diacetylpiperazine with nitrogen-containing nucleophiles

  摘要：

  Reactions of 4,5-diacetoxy-1,3-diacetylimidazolidine and 2,3-diacetoxy-1,4-diacetylpiperazine with acetamide and ethyl carbamate gave 1,3-diacetyl-4,5-bis(acetylamino)imidazolidine, 1,4-diacetyl-2,3-bis(acetylamino)piperazine, 1,3-diacetyl-4,5-bis(ethoxycarbonylamino)imidazolidine, and 1,4-diacetyl-2,3-bis(ethoxycarbonylamino)piperazine, respectively. Condensation products of 4,5-diacetoxy-1,3-diacetylimidazolidine and 2,3-diacetoxy-1,4-diacetylpiperazine with urea, furazan-3,4-diamine, and 4-phenylfurazan-3-amine were isolated.

  DOI：

  10.1134/s1070428007040185

文献信息

• Derivatives of 1,1,2,2-tetraaminoethane: II. Condensation of 4,5-diacetoxy-1,3-diacetylimidazolidine and 2,3-diacetoxy-1,4-diacetylpiperazine with nitrogen-containing nucleophiles
  作者：E. V. Sizova、V. V. Sizov、I. V. Tselinskii

  DOI：10.1134/s1070428007040185

  日期：2007.4

  Reactions of 4,5-diacetoxy-1,3-diacetylimidazolidine and 2,3-diacetoxy-1,4-diacetylpiperazine with acetamide and ethyl carbamate gave 1,3-diacetyl-4,5-bis(acetylamino)imidazolidine, 1,4-diacetyl-2,3-bis(acetylamino)piperazine, 1,3-diacetyl-4,5-bis(ethoxycarbonylamino)imidazolidine, and 1,4-diacetyl-2,3-bis(ethoxycarbonylamino)piperazine, respectively. Condensation products of 4,5-diacetoxy-1,3-diacetylimidazolidine and 2,3-diacetoxy-1,4-diacetylpiperazine with urea, furazan-3,4-diamine, and 4-phenylfurazan-3-amine were isolated.