2-acetoxy-propionic acid tetradecyl ester

• 分子结构分类: 有机化合物 - 脂质和类脂质分子 - 脂肪酰基
• 英文名称: 2-acetoxy-propionic acid tetradecyl ester
• 英文别名: 2-Acetoxy-propionsaeure-tetradecylester；tetradecyl 2-acetyloxypropanoate
• 化学式: C₁₉H₃₆O₄
• 分子量: 328.492
• InChiKey: GSUIFWVFZIMJEO-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  7.1
• 重原子数：
  23
• 可旋转键数：
  17
• 环数：
  0.0
• sp3杂化的碳原子比例：
  0.89
• 拓扑面积：
  52.6
• 氢给体数：
  0
• 氢受体数：
  4

反应信息

• 作为产物：
  描述：

  2-乙酰氧基丙酰氯 、 十四醇 在 吡啶 作用下， 生成 2-acetoxy-propionic acid tetradecyl ester
  参考文献：
  名称：

  n-Alkyl Lactates and their Acetates

  摘要：

  DOI：

  10.1021/ja01161a018

文献信息

• Hair growth composition and method
  申请人：Johnson & Johnson Consumer Inc.

  公开号：US10561593B2

  公开（公告）日：2020-02-18

  The present invention relates to clear compositions for and methods of retarding hair loss or facilitating hair growth comprising a hair growth active, a C8-C24 alcohol ester of a carboxylic acid and a pharmaceutically acceptable topical carrier comprising monohydric and, optionally, dihydric alcohols and water.

  本发明涉及用于延缓脱发或促进毛发生长的透明组合物和方法，该组合物包含一种生发活性物质、一种羧酸的 C8-C24 醇酯和一种药学上可接受的局部载体，该载体包含一元醇和可选的二元醇以及水。
• HAIR GROWTH COMPOSITION AND METHOD
  申请人：Johnson & Johnson Consumer Inc.

  公开号：EP3397348B1

  公开（公告）日：2021-05-19
• Hair Growth Composition and Method
  申请人：Johnson & Johnson Consumer Inc.

  公开号：US20200108004A1

  公开（公告）日：2020-04-09

  The present invention relates to clear compositions for and methods of retarding hair loss or facilitating hair growth comprising a hair growth active, a C 8 -C 24 alcohol ester of a carboxylic acid and a pharmaceutically acceptable topical carrier comprising monohydric and, optionally, dihydric alcohols and water.
• [EN] HAIR GROWTH COMPOSITION AND METHOD<br/>[FR] COMPOSITION ET PROCÉDÉ VISANT À FAVORISER LA POUSSE DES CHEVEUX
  申请人：JOHNSON & JOHNSON CONSUMER INC

  公开号：WO2017116937A1

  公开（公告）日：2017-07-06

  The present invention relates to compositions for and methods of retarding hair loss or facilitating hair growth comprising a hair growth active, a C8-C24 alcohol ester of a carboxylic acid and a viscosity modifying agent comprising: a nonionic hydroxypropylmethyl cellulose and a high molecular weight carboxymethyl cellulose at a ratio of the nonionic hydroxypropylmethyl cellulose to the high molecular weight carboxymethyl cellulose of greater than about 1:1.
• [EN] HAIR GROWTH COMPOSITION AND METHOD<br/>[FR] COMPOSITION ET PROCÉDÉ POUR LA POUSSE DES CHEVEUX
  申请人：JOHNSON & JOHNSON CONSUMER INC

  公开号：WO2017116938A1

  公开（公告）日：2017-07-06

  The present invention relates to compositions for and methods of retarding hair loss or facilitating hair growth comprising a hair growth active, a mixture of C12-C 15 alkyl lactates and a viscosity modifying agent comprising at least one cellulose and/or a cellulose derivative. Clear compositions are also disclosed.