sodium 2,2,2-trichloro-1-(2,2-dimethyl-3-methoxycarbonylcyclopropyl)ethyl carbonate

• 分子结构分类: 有机化合物 - 有机酸及其衍生物 - 羧酸及其衍生物
• 英文名称: sodium 2,2,2-trichloro-1-(2,2-dimethyl-3-methoxycarbonylcyclopropyl)ethyl carbonate
• 英文别名: sodium;[2,2,2-trichloro-1-(3-methoxycarbonyl-2,2-dimethylcyclopropyl)ethyl] carbonate
• 化学式: C₁₀H₁₂Cl₃O₅*Na
• 分子量: 341.551
• InChiKey: VWDTXVIULDMFNV-UHFFFAOYSA-M

计算性质

• 辛醇/水分配系数(LogP)：
  -1.47
• 重原子数：
  19
• 可旋转键数：
  5
• 环数：
  1.0
• sp3杂化的碳原子比例：
  0.8
• 拓扑面积：
  75.7
• 氢给体数：
  0
• 氢受体数：
  5

反应信息

• 作为反应物：
  描述：

  sodium 2,2,2-trichloro-1-(2,2-dimethyl-3-methoxycarbonylcyclopropyl)ethyl carbonate 在 anhydrous phosphorus trichloride 作用下， 生成 2,2,2-trichloro-1-(2,2-dimethyl-3-methoxycarbonylcyclopropyl)ethyl dichlorophosphite
  参考文献：
  名称：

  Trihalocyclopropyl carbonates

  摘要：

  当醛与碱金属三卤乙酸盐在高极性非质子溶剂（DMF，DMSO）存在下反应时，会形成高产率和高速率的新型有机碱金属碳酸盐，这些碳酸盐是拟除虫剂的前体。据称还制得了源自这些碳酸盐的新型磺酸盐和二卤代磷酸酯。

  公开号：

  US04285882A1

文献信息

• Process of preparing dihalovinyl compounds
  申请人：Shell Oil Company

  公开号：US04307243A1

  公开（公告）日：1981-12-22

  Conversion of esters (R.sup.1)(R.sup.2)C(C Hal.sub.3)OX, X being-P Hal.sub.2, --C(O)OR.sup.3 or ##STR1## R.sup.1, R.sup.3 and R.sup.4 being optionally substituted hydrocarbyl groups and R.sup.2 methyl or hydrogen, with zinc in acetic acid gives a very high yield of a dihalovinyl compound (R.sup.1)(R.sup.2)C.dbd.C Hal.sub.2, e.g., of the ethyl ester of the parent acid of pyrethroid insecticides.

  酯（R.sup.1）（R.sup.2）C（C Hal.sub.3）OX的转化，其中X为-P Hal.sub.2，--C（O）OR.sup.3或##STR1##，其中R.sup.1，R.sup.3和R.sup.4是可选择的取代的烃基基团，R.sup.2是甲基或氢，使用乙酸锌可以得到非常高的产率的二卤乙烯化合物（R.sup.1）（R.sup.2）C.dbd.C Hal.sub.2，例如拟除虫菊酯类杀虫剂父酸的乙酯酯。
• Trihalomethylation of aldehydes
  申请人：Shell Oil Company

  公开号：US04388247A1

  公开（公告）日：1983-06-14

  When the reaction of aldehydes with alkali metal trihaloacetates is carried out in the presence of a highly polar aprotic solvent (DMF, DMSO), novel organic alkali metal carbonates, which are precursors of pyrethroid insecticides, are formed in high yields and at a high rate. Novel sulfonates and dihalophosphites, derived from these carbonates have also been claimed.

  当醛类与碱金属三卤乙酸盐在高极性无质子溶剂（DMF，DMSO）存在下反应时，高产率和高速率形成了新型有机碱金属碳酸盐，这些碳酸盐是拟除虫菊酯杀虫剂的前体。据称，这些碳酸盐衍生的新型磺酸盐和二卤代亚磷酸酯也已经被发现。
• Cyclopropyl dihalo phosphites
  申请人：Shell Oil Company

  公开号：US04305890A1

  公开（公告）日：1981-12-15

  When the reaction of aldehydes with alkali metal trihaloacetates is carried out in the presence of a highly polar aprotic solvent (DMF, DMSO), novel organic alkali metal carbonates, which are precursors of pyrethroid insecticides, are formed in high yields and at a high rate. Novel sulfonates and dihalophosphites, derived from these carbonates have also been claimed.

  当醛类与碱金属三卤乙酸盐在高极性的无水溶剂（DMF、DMSO）存在下反应时，会高产率、高速度地形成新型有机碱金属碳酸盐，这些碳酸盐是拟除虫菊酯的前体。同时，还声称得到了从这些碳酸盐衍生的新型磺酸盐和二卤代膦酸酯。
• Novel trihaloethyl carbonate derivatives and a process for their production
  申请人：SHELL INTERNATIONALE RESEARCH MAATSCHAPPIJ B.V.

  公开号：EP0016504A2

  公开（公告）日：1980-10-01

  Process for the preparation of novel trihalomethyl carbonates of the general formula: wherein R1 represents an optionally-substituted cyclopropyl or an optionally-substituted alkyl group, R1 a methyl group or a hydrogen atom or R1 and R2, together with the carbon atom to which they are attached jointly form a cycloalkyl group, each Hal is a chlorine or bromine atom and M represents an alkali metal atom, wherein a carbonyl compound of the general formula: wherein R1 and R have the same meaning as in formula I, is reacted under substantially anhydrous conditions with a trihaloacetate of the general formula: wherein Hal and M have the above-mentioned meaning, in the presence of a highly polar, aprotic inert solvent. The trihalomethyl carbonates are useful as intermediates in the manufacture of pyrethroid insecticides.

  通式如下的新型三卤甲基碳酸盐的制备工艺 其中 R1 代表任选取代的环丙基或任选取代的烷基，R1 代表甲基或氢原子，或 R1 和 R2 连同它们所连接的碳原子共同形成环烷基，每个 Hal 代表氯原子或溴原子，M 代表碱金属原子，其中通式如下的羰基化合物 式中 R1 和 R 的含义与式 I 相同，在基本无水条件下与通式为 其中 Hal 和 M 具有上述含义，在高极性、钝性惰性溶剂存在下进行反应。三卤甲基碳酸盐可用作生产拟除虫菊酯杀虫剂的中间体。
• Process for the preparation of dihalovinyl compounds
  申请人：SHELL INTERNATIONALE RESEARCH MAATSCHAPPIJ B.V.

  公开号：EP0016505A1

  公开（公告）日：1980-10-01

  Process for the preparation of a dihalovinyl compounds of the general formula: wherein R' represents an optionally-substituted cyclopropyl group or an optionally-substituted alkyl group, R2 a methyl group or a hydrogen atom or R' and R2, together with the carbon atom to which they are attached jointly form a cycloalkyl group, and each Hal stands for a chlorine or bromine atom, characterised in that a trihalomethyl compound of the general formula: wherein R', R2 and Hal have the same meaning as in formula I and X represents a group -PQ2, -CO-OR or-SO2-R4 wherein Q represents a halogen atom and R3 and R4 both represent an optionally-substituted alkyl group, is contacted with zinc and an alkanoic acid with up to 5 carbon atoms per molecule: The dihalovinyl compounds are intermediates in the manufacture of pyrethroid insecticides.

  通式如下的二卤乙烯基化合物的制备工艺 其中 R'代表任选取代的环丙基或任选取代的烷基，R2 代表甲基或氢原子或 R'和 R2 与它们所连接的碳原子共同形成环烷基，每个 Hal 代表一个氯原子或溴原子，其特征在于通式的三卤甲基化合物 其中 R'、R2 和 Hal 的含义与式 I 相同，X 代表基团-PQ2、-CO-OR 或-SO2-R4，其中 Q 代表卤素原子，R3 和 R4 均代表任选取代的烷基：二卤乙烯基化合物是生产拟除虫菊酯杀虫剂的中间体。