五氟苯磺酸二均三甲苯基铵盐 | 850629-65-1

• 物质功能分类: 化学试剂 - 有机试剂 - 磺酸盐/亚磺酸盐
• 分子结构分类: 有机化合物 - 苯类化合物 - 苯和取代衍生物
• 中文名称: 五氟苯磺酸二均三甲苯基铵盐
• 英文名称: Dimesitylammonium Pentafluorobenzenesulfonate
• 英文别名: bis(2,4,6-trimethylphenyl)azanium;2,3,4,5,6-pentafluorobenzenesulfonate
• CAS: 850629-65-1
• 化学式: C24H24F5NO3S
• 分子量: 501.5
• InChiKey: MKKHTKBUMNIBLN-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  5.35
• 重原子数：
  34
• 可旋转键数：
  2
• 环数：
  3.0
• sp3杂化的碳原子比例：
  0.25
• 拓扑面积：
  82.2
• 氢给体数：
  1
• 氢受体数：
  8

安全信息

• 海关编码：
  29214990

制备方法与用途

制备方法

用于羧酸和醇的酯化缩合反应。它的一个重要优势是，在反应过程中无需去除副产物水。该催化剂含有大体积的二芳基胺和五氟苯磺酸，NH₂⁺离子附近具有疏水性，这是其活性中心，增加了两个组成部分的空间位阻。因此，在酯化过程中能够促进水的消除，并且酯水解受到限制。这样，所需的酯可以达到很高的产率。

为了展示其多功能性，Ishihara等人报道了该品参与的多种羧酸和醇的酯化缩合反应。例如：使用二级醇作为原料，几乎不会生成烯烃副产物；利用三级醇或苯酚作为原料，相应的酯产率很高。此外，它同样适用于其他不同种类的羧酸，如α,β-未取代羧酸、芳香族羧酸、2-烷氧基羧酸、2-烷基羧酸和4-羰基羧酸等。

五氟苯磺酸的酸度很低

[pKa(CD₃COOD)=11.1, H₀= -3.98]，也可以应用于酸化不稳定基质。

文献信息

• Composition Containing Novel Glutamic Acid Derivative And Block Copolymer, And Use Thereof
  申请人：Nippon Kayaku Kabushiki Kaisha

  公开号：US20200190101A1

  公开（公告）日：2020-06-18

  Provided is a pharmaceutical preparation that is suitable for more effectively exhibiting the efficacy of a glutamic acid derivative, which is a GGT-recognizable prodrug, by producing a composition including a glutamic acid derivative capable of rapidly releasing a physiologically active substance by being recognized by GGT, or a pharmacologically acceptable salt thereof; and a block copolymer in which a polyethylene glycol segment is linked to a polyamino acid segment with a hydrophobic group. Particularly, the composition based on a glutamic acid derivative that uses an antitumor compound as a physiologically active substance is capable of effectively accumulating the glutamic acid derivative at a tumor affected area, exhibits a superior effect against tumors, and is capable of suppressing the release of a physiologically active substance in bone marrow tissue where the expression ratio of GGT is low. Therefore, side effects such as myelosuppression, which pose a problem in the use of antitumor drugs, may be avoided.

  提供的是一种药物制剂，适用于更有效地展现谷氨酸衍生物的功效，该衍生物是一种GGT可识别的前药，通过制备包括一种能够被GGT识别从而快速释放生理活性物质的谷氨酸衍生物或其药理学可接受的盐的组合物；以及一种嵌段共聚物，其中聚乙二醇段与一个疏水基团连接到一个聚氨基酸段。特别是，基于谷氨酸衍生物的组合物使用抗肿瘤化合物作为生理活性物质，能够有效地在受肿瘤影响的区域积累谷氨酸衍生物，对肿瘤具有优越效果，并能够抑制在GGT表达比例较低的骨髓组织中释放生理活性物质。因此，可以避免使用抗肿瘤药物时可能出现的骨髓抑制等副作用。
• [EN] PERFUME SYSTEMS<br/>[FR] SYSTÈMES DE PARFUM
  申请人：PROCTER & GAMBLE

  公开号：WO2015148743A1

  公开（公告）日：2015-10-01

  The present application relates to perfume raw materials, perfume delivery systems and consumer products comprising such perfume raw materials and/or such perfume delivery systems, as well as processes for making and using such perfume raw materials, perfume delivery systems and consumer products. Such perfume raw materials and compositions, including the delivery systems, disclosed herein expand the perfume communities' options as such perfume raw materials can provide variations on character and such compositions can provide desired odor profiles.

  本申请涉及香水原料、香水传递系统和包含这些香水原料和/或香水传递系统的消费品，以及制造和使用这些香水原料、香水传递系统和消费品的过程。本文披露的香水原料和组合物，包括传递系统，扩展了香水社区的选择，因为这些香水原料可以提供不同的特性变化，这些组合物可以提供所需的气味特征。
• (METH)ACRYLIC ACID ESTER COMPOUND AND PRODUCTION METHOD THEREFOR
  申请人：MITSUBISHI GAS CHEMICAL COMPANY, INC.

  公开号：US20170008830A1

  公开（公告）日：2017-01-12

  Provided are a novel alicyclic ester compound and a method for producing a compound of general formula (1) at a high yield from a compound of general formula (2) and a compound of general formula (3). An adamantane compound expressed by general formula (2) and a hydroxyalkyl (meth)acrylate ester compound expressed by general formula (3) are reacted with each other by use of a dehydration condensation agent as a catalyst to obtain an alicyclic ester compound expressed by general formula

  提供了一种新的脂环酯化合物及从一般式(2)和一般式(3)的化合物高产得到一般式(1)化合物的方法。通过使用脱水缩合剂作为催化剂，将一般式(2)表示的金刚烷化合物和一般式(3)表示的羟基烷基（甲基）丙烯酸酯化合物相互反应，得到一种表示为一般式的脂环酯化合物。
• METHOD FOR PRODUCING NOVEL ALI CYCLIC ESTER COMPOUND, NOVEL ALICYCLIC ESTER COMPOUND, (METH)ACRYLIC COPOLYMER PRODUCED BY POLYMERIZING SAID COMPOUND, AND PHOTOSENSITIVE RESIN COMPOSITION USING SAID COPOLYMER
  申请人：MITSUBISHI GAS CHEMICAL COMPANY, INC.

  公开号：US20160355461A1

  公开（公告）日：2016-12-08

  Provided are a resist and a compound for the resist improving the sensitivity, the resolution and the line edge roughness (LER) in a good balance without spoiling basic properties of a chemical amplification resist such as pattern shape, dry etching resistance, heat resistance and the like. Provided are a method for producing an alicyclic ester compound expressed by general formula (1), an alicyclic ester compound expressed by general formula (1), a (meth)acrylic copolymer obtained by polymerization of the alicyclic ester compound, and a photosensitive resin composition containing the (meth)acrylic copolymer. A method for producing an alicyclic ester compound expressed by general formula (1) includes reacting an adamantane compound expressed by general formula (2) with hydroxyalkylamine expressed by general formula (3) to produce an adamantaneamide compound expressed by general formula (4), and then reacting the adamantaneamide compound expressed by general formula (4) with (meth)acrylic acid.

  提供了一种抗蚀剂和化合物，用于在不破坏化学放大抗蚀剂的基本性能（如图案形状、干法蚀刻抗性、耐热性等）的情况下，平衡提高敏感性、分辨率和线边粗糙度（LER）。提供了一种制备由通式（1）表示的脂环酯化合物的方法，一种由通式（1）表示的脂环酯化合物，通过聚合脂环酯化合物得到的（甲）基丙烯酸酯共聚物，以及含有（甲）基丙烯酸酯共聚物的光敏树脂组合物。制备由通式（1）表示的脂环酯化合物的方法包括将由通式（2）表示的金刚烷化合物与由通式（3）表示的羟基烷基胺反应，生成由通式（4）表示的金刚酰胺化合物，然后将由通式（4）表示的金刚酰胺化合物与（甲）基丙烯酸反应。
• METHOD FOR PRODUCING NOVEL ALICYCLIC ESTER COMPOUND, NOVEL ALICYCLIC ESTER COMPOUND, (METH)ACRYLIC COPOLYMER PRODUCED BY POLYMERIZING SAID COMPOUND, AND PHOTOSENSITIVE RESIN COMPOSITION USING SAID COPOLYMER
  申请人：Mitsubishi Gas Chemical Company, Inc.

  公开号：EP3106454A1

  公开（公告）日：2016-12-21

  Provided are a resist and a compound for the resist improving the sensitivity, the resolution and the line edge roughness (LER) in a good balance without spoiling basic properties of a chemical amplification resist such as pattern shape, dry etching resistance, heat resistance and the like. Provided are a method for producing an alicyclic ester compound expressed by general formula (1), an alicyclic ester compound expressed by general formula (1), a (meth)acrylic copolymer obtained by polymerization of the alicyclic ester compound, and a photosensitive resin composition containing the (meth)acrylic copolymer. A method for producing an alicyclic ester compound expressed by general formula (1) includes reacting an adamantane compound expressed by general formula (2) with hydroxyalkylamine expressed by general formula (3) to produce an adamantaneamide compound expressed by general formula (4), and then reacting the adamantaneamide compound expressed by general formula (4) with (meth)acrylic acid.

  本发明提供了一种光刻胶和一种光刻胶用化合物，在不破坏化学放大光刻胶的基本特性（如图案形状、耐干蚀性、耐热性等）的情况下，以良好的平衡提高了光刻胶的灵敏度、分辨率和线边缘粗糙度（LER）。本发明提供了一种生产通式（1）表示的脂环族酯化合物的方法、一种通式（1）表示的脂环族酯化合物、一种由脂环族酯化合物聚合得到的（甲基）丙烯酸共聚物以及一种含有该（甲基）丙烯酸共聚物的感光树脂组合物。生产通式(1)表示的脂环酯化合物的方法包括将通式(2)表示的金刚烷化合物与通式(3)表示的羟基烷基胺反应生成通式(4)表示的金刚烷酰胺化合物，然后将通式(4)表示的金刚烷酰胺化合物与(甲基)丙烯酸反应。