(E)-β-styryl 2-bromopropanoate

• 分子结构分类: 有机化合物 - 苯类化合物 - 苯和取代衍生物
• 英文名称: (E)-β-styryl 2-bromopropanoate
• 英文别名: [(E)-2-phenylethenyl] 2-bromopropanoate
• 化学式: C₁₁H₁₁BrO₂
• 分子量: 255.111
• InChiKey: VMGZPIOORCUWMP-BQYQJAHWSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  3.3
• 重原子数：
  14
• 可旋转键数：
  4
• 环数：
  1.0
• sp3杂化的碳原子比例：
  0.18
• 拓扑面积：
  26.3
• 氢给体数：
  0
• 氢受体数：
  2

反应信息

• 作为产物：
  描述：

  2-溴丙酸 、 苯乙炔 在 bis[dicarbonylcyclopentadienylruthenium(I)] 作用下， 以 甲苯 为溶剂， 反应 24.0h， 生成 (Z)-β-styryl 2-bromopropanoate 、 (E)-β-styryl 2-bromopropanoate 、
  参考文献：
  名称：

  Regio- and stereoselective addition of carboxylic acids to phenylacetylene catalyzed by cyclopentadienyl ruthenium complexes

  摘要：

  The direct addition of carboxylic acids to terminal alkynes Such as phenylacetylene in the presence of catalytic amount of [CpRu(CO)(2)CI] (1) or [{CpRu(CO)(2)}(2)] (2) affords the anti-Markovnikov adducts with high selectivity. In most instances, the E-enol esters are the major products. (c) 2005 Elsevier B.V. All rights reserved.

  DOI：

  10.1016/j.jorganchem.2005.11.023

文献信息

• Regio- and stereoselective addition of carboxylic acids to phenylacetylene catalyzed by cyclopentadienyl ruthenium complexes
  作者：Suming Ye、Weng Kee Leong

  DOI：10.1016/j.jorganchem.2005.11.023

  日期：2006.3

  The direct addition of carboxylic acids to terminal alkynes Such as phenylacetylene in the presence of catalytic amount of [CpRu(CO)(2)CI] (1) or [CpRu(CO)(2)}(2)] (2) affords the anti-Markovnikov adducts with high selectivity. In most instances, the E-enol esters are the major products. (c) 2005 Elsevier B.V. All rights reserved.