perfluorooctyl amine | 4220-20-6

• 分子结构分类: 有机化合物 - 有机卤素化合物 - 有机氟化物
• 英文名称: perfluorooctyl amine
• 英文别名: Perfluoro-1-octanamine；1,1,2,2,3,3,4,4,5,5,6,6,7,7,8,8,8-heptadecafluorooctan-1-amine
• CAS: 4220-20-6
• 化学式: C₈H₂F₁₇N
• 分子量: 435.083
• InChiKey: HLYYHSGXXMZHEN-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  5.2
• 重原子数：
  26
• 可旋转键数：
  6
• 环数：
  0.0
• sp3杂化的碳原子比例：
  1.0
• 拓扑面积：
  26
• 氢给体数：
  1
• 氢受体数：
  18

反应信息

• 作为产物：
  描述：

  全氟辛酸 以 甲醇 、 BF₃ (30w/v(methanol) 、 水 为溶剂， 生成 perfluorooctyl amine
  参考文献：
  名称：

  Biguanide derivatives and biocidal compositions containing them

  摘要：

  一种抗微生物化合物，包括：其中 Q = 苯基; Y = -H 或 -甲基; R = -(CF₂)yCF₃，其中 y = 1 - 20，-(CH₂)x-O-CxH2X+1，其中 x = 1 - 25，-(CH₂CH₂O)n(CH(CH₃)CH₂O)m(CH₂CH(CH₃)O)p(CH₂CH₂O)qT，其中 T = -H 或支链或非支链C₁₋₂₀烷基，n，m，p，q = 0 - 99，且n + m + p + q ≧ 1，-CHR'COOH，其中R'是天然存在的氨基酸侧链，或(CH₂)xCOOH;和A = -H，-OH，NH₂，-CH₂ = CH₂，-(CH₂CH₂O)n(CH(CH₃)CH₂O)m(CH₂CH(CH₃)O)p(CH₂CH₂O)qT，胺蛋白连接，胺糖连接，多羟胺连接或-COOX，其中X = -H，氨基醇基团，氨基烷氧基硅烷基团，-CONH(CH₂)xCOOH，或-NHCH₂CH-(OX')₂，其中X' = 甲基或乙基。这种新型生物杀灭化合物也可以与蛋白质和多糖结合，并且在各种溶液和典型的生物杀灭方案或治疗部位中稳定。发明的生物杀灭化合物对革兰氏阳性和革兰氏阴性细菌均具有改善的抗菌效果，可以具有对各种其他微生物包括病毒，酵母菌，霉菌等的生物杀灭活性，并且可以对多细胞害虫产生活性。

  公开号：

  EP0456093A3

文献信息

• Perfluoroalkyl-containing complexes, process for their production as well as their use
  申请人：Schirmer Heiko

  公开号：US20070020183A1

  公开（公告）日：2007-01-25

  The invention relates to the subjects that are characterized in the claims, namely perfluoroalkyl-containing metal complexes with an N-alkyl group of general formula 1, process for their production and their use in NMR and x-ray diagnosis, radiodiagnosis, and radiotherapy, as well as in MRT lymphography.

  该发明涉及到声明中所描述的主题，即具有通用公式1中的N-烷基基团的全氟烷基含金属络合物，其生产过程以及它们在核磁共振和X射线诊断、放射诊断和放射治疗以及MRT淋巴造影中的用途。
• Compositions, Methods and Kits for Treating a Contact Lens
  申请人：QIN GUOTING

  公开号：US20190133932A1

  公开（公告）日：2019-05-09

  Provided herein are fluorinated compounds having chemical structures: (I) where n is 0 or greater, or (II) where m and n are 0 or greater, or an amino acid, a soluble polymer, an oligo(ethylene glycol), a poly(ethylene glycol), or a carbohydrate each fluorinated with perfluorocarbons having the chemical structure (III) where n is 0 or greater. These fluorinated compounds are utilized in contact lenses to impart lipid-resistant, protein-resistant and biofouling-resistant properties, thus reducing discomfort and infection caused by contact lens wear without changing its transmission characteristics. Also provided is an ophthalmic drug delivery system comprising at least one of the compounds described above embedded in the contact lens and a kit to incorporate the ophthalmic into a contact lens. Methods for incorporating these compounds onto a contact lens without affecting transparency and for use in treating an ophthalmologic-associated condition are provided.

  本文提供了具有化学结构的氟化合物：（I）其中n为0或更大，或（II）其中m和n为0或更大，或氨基酸、可溶性聚合物、寡聚乙二醇、聚乙二醇或碳水化合物，每种都用具有化学结构的全氟碳化合物氟化（III）其中n为0或更大。这些氟化合物用于隐形眼镜中，赋予其抗脂质、抗蛋白质和抗生物污染的特性，从而减少隐形眼镜佩戴引起的不适和感染，而不改变其透射特性。还提供了一种眼科药物输送系统，包括至少一种嵌入隐形眼镜中的上述化合物，以及一个将眼科药物嵌入隐形眼镜的工具包。提供了将这些化合物嵌入隐形眼镜中而不影响透明度的方法，以及用于治疗眼科相关疾病的方法。
• Methods for Making Functionalized Fluorinated Monomers, Fluorinated Monomers, and Compositions for Making the Same
  申请人：Etna-TEC, Ltd.

  公开号：US20180334417A1

  公开（公告）日：2018-11-22

  A method of making a functionalized fluorinated monomer for use in making oligomers and polymers that can be used to improve surface properties of polymer-derived systems, such as coatings. The method of making a functionalized fluorinated monomer includes reacting at least one fluorinated nucleophilic reactant, such as a fluorinated alcohol, with at least one compound containing at least one epoxide group. Other methods include reaction of a fluorinated alcohol with a cyclic carboxylic anhydride. In another embodiment, a method includes reacting a fluorinated mesylate, tosylate or triflate with an amine, alkoxide or phenoxide. In other embodiments, the method includes reacting a fluorinated alcohol with an alkyl halide, or reacting a fluorinated alkyl halide with an amine. The functionalized fluorinated monomers may be used as intermediates and reacted to modify the functional groups thereon. Further, the functionalized fluorinated monomers may be reacted to form polymers or oligomers, or with polymers or oligomers having functional groups to modify the polymer or oligomer through the functional group thereon,

  一种制备用于制备寡聚物和聚合物的官能化氟化单体的方法，可用于改善聚合物衍生系统（如涂层）的表面性能。制备官能化氟化单体的方法包括将至少一种氟化亲核试剂（如氟化醇）与至少一种含有至少一个环氧基团的化合物反应。其他方法包括将氟化醇与环状羧酸酐反应。在另一实施例中，一种方法包括将氟化甲磺酸酯、对甲苯磺酸酯或三氟甲烷磺酸酯与胺、烷氧基或苯氧基反应。在其他实施例中，该方法包括将氟化醇与烷基卤化物反应，或将氟化烷基卤化物与胺反应。这些官能化氟化单体可用作中间体，并可反应以修改其上的官能基团。此外，这些官能化氟化单体可用于与聚合物或寡聚物反应，或与具有官能基团的聚合物或寡聚物反应，通过其上的官能基团修改聚合物或寡聚物。
• Process for producing compound, catalyst component for addition polymerization, process for producing catalyst for addition polymerization, and process for producing addition polymer
  申请人：Oshima Hideki

  公开号：US20050222351A1

  公开（公告）日：2005-10-06

  There are provided (1) a process for producing a compound, which comprises the step of contacting a compound (A) defined by the formula, M 1 L 1 3 , a compound (B) defined by the formula, R 1 t-1 TH, and a compound (C) defined by the formula, R 2 t-2 TH 2 ; (2) a catalyst component for addition polymerization, which comprises a compound produced by said process; (3) a process for producing a polymerization catalyst, which comprises the step of contacting said catalyst component with a transition metal compound and an optional organoaluminum compound; and (4) a process for producing an addition polymer, which comprises the step of addition polymerizing an addition polymerizable monomer in the presence of a catalyst produced by said process.

  提供以下内容：（1）生产化合物的过程，包括将由M1L13公式定义的化合物（A）、由R1t-1TH公式定义的化合物（B）和由R2t-2TH2公式定义的化合物（C）接触的步骤；（2）用于加成聚合的催化剂组分，包括通过上述过程产生的化合物；（3）生产聚合催化剂的过程，包括将催化剂组分与过渡金属化合物和可选的有机铝化合物接触的步骤；（4）生产加成聚合物的过程，包括在上述过程产生的催化剂存在下加成聚合可聚合单体的步骤。
• Fluorinated dyes or colorants and their uses
  申请人：Yang Jin

  公开号：US20050039274A1

  公开（公告）日：2005-02-24

  This invention relates to novel fluorinated dyes or colorants having high solubility and low viscosity in halogenated, especially fluorinated, solvents. The dyes or colorants of the present invention have shown to improve the performance of electrophoretic displays.

  本发明涉及具有高溶解度和低黏度的新型氟化染料或着色剂，在卤化物，特别是氟化物溶剂中具有高溶解度和低黏度。本发明的染料或着色剂已经表明可以提高电泳显示器的性能。