S-phenyl dithiocarbonate

• 分子结构分类: 有机化合物 - 有机硫化合物 - 硫醚类
• 英文名称: S-phenyl dithiocarbonate
• 英文别名: phenylsulfanylmethanethioic S-acid
• 化学式: C₇H₆OS₂
• 分子量: 170.256
• InChiKey: LUCZGTXVPODASE-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  2.8
• 重原子数：
  10
• 可旋转键数：
  2
• 环数：
  1.0
• sp3杂化的碳原子比例：
  0.0
• 拓扑面积：
  43.4
• 氢给体数：
  1
• 氢受体数：
  3

反应信息

• 作为产物：
  描述：

  氯代二硫代甲酸苯基酯 在 水 作用下， 以 丙酮 为溶剂， 生成 S-phenyl dithiocarbonate
  参考文献：
  名称：

  Correlation of the rates of solvolysis of phenyl chlorothionoformate and phenyl chlorodithioformate

  摘要：

  The specific rates of solvolysis of phenyl chlorothionoformate (PhOCSCl) are remarkably similar to those previously reported for phenyl chlorothioformate (PhSCOCl). When analyzed using the extended Grunwald-Winstein equation over the usual range of solvent types, these solvolyses show essentially identical divisions into the solvents favoring the addition-elimination channel and those favoring the ionization channel. The introduction of one sulfur caused a partial shift away from the addition-elimination pathway, which was dominant over the full range of solvents for phenyl chloroformate (PhOCOCl). Consistent with these results, introduction of the second sulfur within phenyl chlorodithioformate (PhSCSCl) leads to a completion of this shift, such that an extended Grunwald-Winstein treatment of the specific rates of solvolysis now shows the ionization pathway to be dominant over the full range of solvents.

  DOI：

  10.1139/cjc-77-5-6-1118

文献信息

• Paromomycin derivatives, a process for the preparation thereof and therapeutical composition containing them
  申请人：FARMITALIA CARLO ERBA S.p.A.

  公开号：EP0021150A1

  公开（公告）日：1981-01-07

  Paromomycin derivatives of the formula wherein R1 represents a hydrogen or chlorine atom, and their pharmaceutically acceptable addition salts. Different methods of producing these derivatives starting from 4',6'-O-benzylidene-penta-N-benzyloxycarbonylparomomycin are also disclosed. The compounds (I) and their pharmaceutically acceptable acid addition salts are useful as active ingredient in therapeutical compositions and as antibiotics for the treatment of amoebic disentery, shigellosis and salmonellosis.

  式中的巴龙霉素衍生物 其中 R1 代表氢原子或氯原子，以及它们的药学上可接受的加成盐。此外，还公开了从 4',6'-O-亚苄基-五-N-苄氧羰基巴龙霉素开始生产这些衍生物的不同方法。化合物 (I) 及其药学上可接受的酸加成盐可作为治疗组合物的活性成分，也可作为抗生素用于治疗阿米巴痢疾、志贺氏菌病和沙门氏菌病。
• A New Method for the Synthesis of Alkyl Aryl Sulfides
  作者：Hiroshi Yoshida、Saburo Inokawa、Tsuyoshi Ogata

  DOI：10.1246/bcsj.39.411

  日期：1966.2
• US3954994A
  申请人：——

  公开号：US3954994A

  公开（公告）日：1976-05-04
• US4337248A
  申请人：——

  公开号：US4337248A

  公开（公告）日：1982-06-29
• [EN] MACRO-RAFT CHAIN TRANSFER AGENTS AS ANIONIC POLYMERIZATION TERMINATORS<br/>[FR] AGENTS DE TRANSFERT DE CHAÎNE MACRO-RAFT UTILISÉS EN TANT QUE TERMINATEURS DE POLYMÉRISATION ANIONIQUE
  申请人：UNIV IOWA STATE RES FOUND INC

  公开号：WO2018183261A1

  公开（公告）日：2018-10-04

  The present invention relates to a compound of Formula (I): where ℗ R, R1, R2, R3, and Z are as described herein and to a process for preparing a compound of Formula (I). This invention also relates to a process for the synthesis of a polymer which includes providing a monomer composition, providing a compound of Formula (I), and polymerizing monomers within the monomer composition through controlled free radical polymerization with the compound of Formula (I) to form the polymer.