[9]anthryl-hydrazine-N,N'-dicarboxylic acid diethyl ester

• 分子结构分类: 有机化合物 - 苯类化合物 - 蒽
• 英文名称: [9]anthryl-hydrazine-N,N'-dicarboxylic acid diethyl ester
• 英文别名: [9]Anthryl-hydrazin-N,N'-dicarbonsaeure-diaethylester；Anthryl-(9)-bicarbamidsaeure-diaethylester；ethyl N-anthracen-9-yl-N-(ethoxycarbonylamino)carbamate
• 化学式: C₂₀H₂₀N₂O₄
• 分子量: 352.39
• InChiKey: KDKJIIFEIPFTLI-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  4.8
• 重原子数：
  26
• 可旋转键数：
  5
• 环数：
  3.0
• sp3杂化的碳原子比例：
  0.2
• 拓扑面积：
  67.9
• 氢给体数：
  1
• 氢受体数：
  4

反应信息

• 作为产物：
  描述：

  alkaline earth salt of/the/ methylsulfuric acid 在 盐酸 、 溶剂黄146 作用下， 生成 [9]anthryl-hydrazine-N,N'-dicarboxylic acid diethyl ester
  参考文献：
  名称：

  Diels et al., Chemische Berichte, 1938, vol. 71, p. 1189,1196

  摘要：

  DOI：

文献信息

• Sc(OTf)₃Catalyzed Electrophilic Amination of Arenes: An Expeditious Synthesis of Aryl Hydrazides
  作者：J. S. Yadav、B. V. S. Reddy、G. Veerendhar、R. Srinivasa Rao、K. Nagaiah

  DOI：10.1246/cl.2002.318

  日期：2002.3

  Arenes react smoothly with diethyl azodicarboxylate in the presence of a catalytic amount of scandium triflate in dichloromethane at ambient temperature to afford the corresponding aryl hydrazides in high yields with high regioselectivity.

  在二氯甲烷中，于常温下，芳烃在催化量的三氟甲磺酸钪存在下顺利地与偶氮二甲酸二乙酯反应，以高区域选择性及高产率生成相应的芳基酰肼。
• FUNCTIONAL, CROSS-LINKED NANOSTRUCTURES FOR TANDEM OPTICAL IMAGING AND THERAPY
  申请人：Mallinckrodt LLC

  公开号：EP2571529A2

  公开（公告）日：2013-03-27
• Functional, Cross-Linked Nanostructures for Tandem Optical Imaging and Therapy
  申请人：Neumann William L.

  公开号：US20130137976A1

  公开（公告）日：2013-05-30

  The present invention provides optical agents comprising optically functional cross linked supramolecular structures and assemblies useful for tandem optical imaging and therapy. Supramolecular structures and assemblies of the present invention include optically functional shell-cross linked micelles wherein optical functionality is achieved via incorporation of one or more linking groups that include one or more photoactive moieties. The present invention further includes imaging and therapeutic methods using one or more optical agents of the present invention including optically functional shell cross-linked micelles having an associated therapeutic agent.
• US8731655B2
  申请人：——

  公开号：US8731655B2

  公开（公告）日：2014-05-20
• US9295650B2
  申请人：——

  公开号：US9295650B2

  公开（公告）日：2016-03-29