六氯偶锑酸二氯(苯基)甲鎓 | 4257-92-5

• 分子结构分类: 有机化合物 - 有机酸及其衍生物 - 羧酸及其衍生物
• 中文名称: 六氯偶锑酸二氯(苯基)甲鎓
• 中文别名: 组氨酰-脯氨酸二氧代哌嗪
• 英文名称: cyclic histidylproline
• 英文别名: cyclo-(histidine-proline)；cyclo(His-Pro)；Histidyl-prolin-anhydrid；Histidylprolindiketopiperazin；3-(1(3)H-imidazol-4-ylmethyl)-hexahydro-pyrrolo[1,2-a]pyrazine-1,4-dione；3-(1H-imidazol-5-ylmethyl)-2,3,6,7,8,8a-hexahydropyrrolo[1,2-a]pyrazine-1,4-dione
• CAS: 4257-92-5
• 化学式: C₁₁H₁₄N₄O₂
• 分子量: 234.258
• InChiKey: NAKUGCPAQTUSBE-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  -0.4
• 重原子数：
  17
• 可旋转键数：
  2
• 环数：
  3.0
• sp3杂化的碳原子比例：
  0.55
• 拓扑面积：
  78.1
• 氢给体数：
  2
• 氢受体数：
  3

反应信息

• 作为产物：
  描述：

  组氨酸脯氨酸酰胺 生成 六氯偶锑酸二氯(苯基)甲鎓
  参考文献：
  名称：

  Moess, Judi; Bundgaard, Hans, Journal of Pharmacy and Pharmacology, 1990, vol. 42, # 1, p. 7 - 12

  摘要：

  DOI：

文献信息

• Advanced drug development and manufacturing
  申请人：Los Alamos National Security, LLC

  公开号：EP2511844A2

  公开（公告）日：2012-10-17

  There is described an apparatus for measuring protein characteristics comprising an X-ray fluorescence (XRF) spectrometer comprising a source of polychromatic X-rays, an X-ray detector, a protein, a molecule that has been exposed to and at least weakly binds to the protein, a plurality of X-ray fluorescence signal data obtained by irradiating chemical elements in the protein and molecule with the polychromatic X-rays and a security system for maintaining records for the data from the plurality of X-ray fluorescence signal measurements. There is also described an x-ray microscope for measuring a sample.

  描述了一种测量蛋白质特性的仪器，该仪器包括一个 X 射线荧光 (XRF) 光谱仪，其中包括一个多色 X 射线源、一个 X 射线探测器、一个蛋白质、一个已暴露于该蛋白质并至少与该蛋白质弱结合的分子、通过用多色 X 射线照射蛋白质和分子中的化学元素而获得的多个 X 射线荧光信号数据，以及一个用于维护多个 X 射线荧光信号测量数据记录的安全系统。此外，还介绍了一种用于测量样品的 X 射线显微镜。
• AGRICULTURAL CHEMICAL CONTAINING 2,5-DIKETOPIPERAZINE DERIVATIVE AS ACTIVE INGREDIENT
  申请人：Republic of Korea (Management: Rural Development Administration)

  公开号：EP2594134A2

  公开（公告）日：2013-05-22

  Disclosed herein is an agricultural agent containing a 2,5-diketopiperazine derivative capable of controlling plant diseases and promoting plant growth or an agriculturally acceptable salt thereof as an active ingredient.

  本文公开了一种农用制剂，其活性成分含有能够控制植物病害和促进植物生长的 2,5-二酮哌嗪衍生物或其农业上可接受的盐。
• PLANT EXTRACT CONTAINING DIKETOPIPERAZINE AND METHOD FOR PRODUCING SAME
  申请人：Suntory Holdings Limited

  公开号：EP3012264A1

  公开（公告）日：2016-04-27

  Provided are a diketopiperazine mixture suitable for mixing with a food or drink and a method for producing the mixture. High-temperature and high-pressure treatment of plant peptides in a liquid allows production of a plant extract containing a high concentration of diketopiperazines including cyclo-leucyl-leucine and cyclo-leucyl-phenylalanine. The present invention can provide diketopiperazines having excellent flavor derived from a plant natural product and can produce a food or drink provided with the functions of the diketopiperazines by directly mixing the diketopiperazines with the food or drink.

  本发明提供了一种适合与食品或饮料混合的二酮哌嗪混合物以及生产该混合物的方法。在液体中对植物肽进行高温高压处理，可以生产出一种含有高浓度二酮哌嗪的植物提取物，其中包括环亮氨酸和环亮氨酸-苯丙氨酸。本发明可提供从植物天然产物中提取的具有极佳风味的二酮哌嗪，并可通过直接将二酮哌嗪与食品或饮料混合，生产出具有二酮哌嗪功能的食品或饮料。
• Polymorphic forms of Cyclo (-His-Pro)
  申请人：NovMetaPharma Co., Ltd.

  公开号：US10683300B2

  公开（公告）日：2020-06-16

  The present disclosure relates to synthesis and characterization of novel polymorphic forms of Cyclo (-His-Pro) (“CHP”).

  本公开涉及新型多晶态环（-His-Pro）（"CHP"）的合成和表征。
• Plant extract containing diketopiperazine and method for producing same
  申请人：SUNTORY HOLDINGS LIMITED

  公开号：US11382911B2

  公开（公告）日：2022-07-12

  A diketopiperazine mixture suitable for mixing with a food or drink and a method for producing the mixture. High-temperature and high-pressure treatment of plant peptides in a liquid allows production of a plant extract containing a high concentration of diketopiperazines including cyclo-leucyl-leucine and cyclo-leucyl-phenylalanine. Diketopiperazines having excellent flavor derived from a plant natural product and can produce a food or drink provided with the functions of the diketopiperazines by directly mixing the diketopiperazines with the food or drink.

  一种适合与食品或饮料混合的二酮哌嗪混合物以及生产这种混合物的方法。在液体中对植物肽进行高温高压处理，可以生产出一种含有高浓度二酮哌嗪的植物提取物，其中包括环亮氨酸和环亮氨酸-苯丙氨酸。从植物天然产物中提取的二酮哌嗪具有极佳的风味，直接将二酮哌嗪与食品或饮料混合，即可生产出具有二酮哌嗪功能的食品或饮料。