(E)-(R)-6-Methyl-hept-3-en-2-ol

• 分子结构分类: 有机化合物 - 脂质和类脂质分子 - 脂肪酰基
• 英文名称: (E)-(R)-6-Methyl-hept-3-en-2-ol
• 英文别名: (E,2R)-6-methylhept-3-en-2-ol
• 化学式: C₈H₁₆O
• 分子量: 128.214
• InChiKey: WZSFWDMBHKLHBI-YZCDNWJKSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  2
• 重原子数：
  9
• 可旋转键数：
  3
• 环数：
  0.0
• sp3杂化的碳原子比例：
  0.75
• 拓扑面积：
  20.2
• 氢给体数：
  1
• 氢受体数：
  1

反应信息

• 作为产物：
  描述：

  Acetic acid (E)-(R)-1,5-dimethyl-hex-2-enyl ester 在 水 作用下， 生成 (E)-(R)-6-Methyl-hept-3-en-2-ol
  参考文献：
  名称：

  Dynamic Kinetic Resolution of Allylic Alcohols Mediated by Ruthenium- and Lipase-Based Catalysts

  摘要：

  [GRAPHICS]An enzyme-metal combo reaction has been developed for the dynamic kinetic resolution of allylic alcohols in which racemic substrates are transformed by a lipase and a ruthenium complex in the presence of an acyl donor to allylic acetates of high optical purity in over 80% yield.

  DOI：

  10.1021/ol006159y

文献信息

• Dynamic Kinetic Resolution of Allylic Alcohols Mediated by Ruthenium- and Lipase-Based Catalysts
  作者：Donghyun Lee、Eun A. Huh、Mahn-Joo Kim、Hyun Min Jung、Jeong Hwan Koh、Jaiwook Park

  DOI：10.1021/ol006159y

  日期：2000.7.1

  [GRAPHICS]An enzyme-metal combo reaction has been developed for the dynamic kinetic resolution of allylic alcohols in which racemic substrates are transformed by a lipase and a ruthenium complex in the presence of an acyl donor to allylic acetates of high optical purity in over 80% yield.