4-ethoxy-4-(4-nitrophenyl)-1-butene

• 分子结构分类: 有机化合物 - 苯类化合物 - 苯和取代衍生物
• 英文名称: 4-ethoxy-4-(4-nitrophenyl)-1-butene
• 英文别名: 1-(1-Ethoxybut-3-enyl)-4-nitrobenzene
• 化学式: C₁₂H₁₅NO₃
• 分子量: 221.256
• InChiKey: MLEUZWGTIWBQKM-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  2.9
• 重原子数：
  16
• 可旋转键数：
  5
• 环数：
  1.0
• sp3杂化的碳原子比例：
  0.33
• 拓扑面积：
  55
• 氢给体数：
  0
• 氢受体数：
  3

反应信息

• 作为产物：
  描述：

  烯丙基三乙氧基硅烷 、 对硝基苯甲醛 在 indium(III) chloride 三甲基氯硅烷 作用下， 以 二氯甲烷 为溶剂， 反应 3.0h， 以99%的产率得到4-ethoxy-4-(4-nitrophenyl)-1-butene
  参考文献：
  名称：

  铟与功能性硅烷的高效铟催化化学选择性烯丙基化-醚化和还原醚化

  摘要：

  氯化铟（III）是一种有效的路易斯酸催化剂，可在室温下一锅化芳族醛与官能硅烷，烯丙基三乙氧基硅烷和三乙氧基硅烷的烯丙基化—醚化和还原醚化，从而以优异的收率提供相应的醚。另外，在TMSC1存在下，InCl 3催化的反应提供了明显的优点，因为其易于处理以在温和条件下制备不对称醚。

  DOI：

  10.1016/j.tetlet.2007.11.062

文献信息

• Selective hydrogenation of nitroarenes under mild conditions by the optimization of active sites in a well defined Co@NC catalyst
  作者：Shuo Chen、Li-Li Ling、Shun-Feng Jiang、Hong Jiang

  DOI：10.1039/d0gc01835j

  日期：——

  aromatic nitro compounds containing multiple functional groups into amino compounds with high conversion rates, selectivity, and stability under mild conditions is a great challenge. Herein, a well defined catalyst (Co@NC) is prepared through the pyrolysis of the Co-centered metal–organic framework (MOF) at the optimized temperature. The as-synthesized catalyst exhibits a high conversion rate and selectivity

  在温和条件下以高转化率，选择性和稳定性将含有多个官能团的芳族硝基化合物催化氢化为氨基化合物是一个巨大的挑战。在此，通过在最佳温度下对以Co为中心的金属-有机骨架（MOF）进行热解制备了定义明确的催化剂（Co @ NC）。所合成的催化剂在温和的条件下（80°C，30分钟和1个大气压），具有12种具有不同竞争基团的芳族硝基化合物与水合肼的氢化反应，具有较高的转化率和选择性。该催化剂还显示出优异的稳定性，可以重复使用20次以上，而不会显着降低其活性。发现Co–Nx位点是催化氢化的主要活性位点，Co NPs和N掺杂碳之间的Mott–Schottky效应可以进一步促进氢化反应。EXAFS，TEM，XPS和Raman分析证实，钴纳米颗粒（NPs）在最佳温度下被N掺杂的碳基质正确封装，并且Co物种在催化后保持高自旋状态，这可能是导致碳纳米管形成的原因。 Co @ NC的高性能。这项工作不仅证明了在温和条
• Host (Nanocavity of Aluminium-Incorporated Mesoporous KIT-6)–guest (12-tungesto(molybdato) Phosphoric Acid) Nanocomposite Material: Efficient and Reusable Catalysts for the Hosomi–Sakurai Three-Component Coupling Reaction
  作者：Razieh Fazaeli、Hamid Aliyan、Elham Naderi

  DOI：10.1080/10426507.2012.704100

  日期：2013.6.1

  The immobilization of heteropoly acids (HPAs) into the Al-functionalized KIT-6 mesoporous molecular sieve has been carried out to see the effect of Al-KIT-6 as a host matrix on the HPA activities. These modified mesoporous molecular sieves are effective catalysts for the Hosomi-Sakurai three-component coupling reaction via condensation of aldehydes, silyl ethers, and allylsilanes. Supplemental materials are available for this paper. Go to the publisher's online edition of Phosphorus, Sulfur, and Silicon and the Related Elements to view the free supplemental file.
• Cesium Salt of Tungstosilicic Acid Fabricated by Nano-Casting Strategy: An Efficient Catalyst for the Three-Component Hosomi–Sakurai Reaction
  作者：Razieh Fazaeli、Hamid Aliyan、Mohammad Javad Bagi

  DOI：10.1080/10426507.2011.639821

  日期：2012.6

  We have used SBA-15 silicas as hard templates for the nano-fabrication of Cs1.8H2.2SiW12O40 (CsHSiW) salt nanocrystal. The elimination by HF (or NaOH 90 degrees C) in the silica matrix from the composites occurred by a two-step reaction deposition of CsHSiW salt nanocrystal. The nano-casted CsHPW materials were characterized by several techniques: chemical analysis (atomic absorption, neutron activation analysis, and inductively coupled plasma) and spectroscopic methods (FT-IR spectrum, X-ray diffraction, transmission electron microscopy, and energy dispersive x-ray analysis measurement). In addition to the complete characterization of CsHSiW nanocrystal samples, their catalytic performances are shown for the three-component Hosomi-Sakurai reaction. The reaction proceeds efficiently under ambient conditions with good to excellent yields.
• Highly efficient indium-catalyzed chemoselective allylation–etherification and reductive etherification of aromatic aldehydes with functional silanes
  作者：Ming-Song Yang、Li-Wen Xu、Hua-Yu Qiu、Guo-Qiao Lai、Jian-Xiong Jiang

  DOI：10.1016/j.tetlet.2007.11.062

  日期：2008.1

  Indium(III) chloride is an effective Lewis acid catalyst for one-pot allylation–etherification and reductive etherification of aromatic aldehydes with functional silanes, allyltriethoxysilane, and triethoxysilane, at room temperature to afford corresponding ethers in excellent yields. Additionally, the InCl3-catalyzed reactions in the presence of TMSCl offer significant advantages in its ease of working-up

  氯化铟（III）是一种有效的路易斯酸催化剂，可在室温下一锅化芳族醛与官能硅烷，烯丙基三乙氧基硅烷和三乙氧基硅烷的烯丙基化—醚化和还原醚化，从而以优异的收率提供相应的醚。另外，在TMSC1存在下，InCl 3催化的反应提供了明显的优点，因为其易于处理以在温和条件下制备不对称醚。