methyl 2-[(2-amino-6-methylpyrimidin-4-yl)thio]acetate

• 分子结构分类: 有机化合物 - 有机硫化合物 - 硫醚类
• 英文名称: methyl 2-[(2-amino-6-methylpyrimidin-4-yl)thio]acetate
• 英文别名: Methyl 2-[(2-amino-6-methylpyrimidin-4-YL)sulfanyl]acetate；methyl 2-(2-amino-6-methylpyrimidin-4-yl)sulfanylacetate
• 化学式: C₈H₁₁N₃O₂S
• 分子量: 213.26
• InChiKey: SFUTVCZCCZLLNK-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  1
• 重原子数：
  14
• 可旋转键数：
  4
• 环数：
  1.0
• sp3杂化的碳原子比例：
  0.38
• 拓扑面积：
  103
• 氢给体数：
  1
• 氢受体数：
  6

反应信息

• 作为反应物：
  描述：

  methyl 2-[(2-amino-6-methylpyrimidin-4-yl)thio]acetate 在 hydrazine hydrate 作用下， 以 异丙醇 为溶剂， 以85%的产率得到2-[(2-amino-6-methylpyrimidin-4-yl)sulfanyl]-acetohydrazide
  参考文献：
  名称：

  Synthesis and Plant Growth Stimulating Action of 2-Amino-6-methylpyrimidine-4(3H)-thione Derivatives

  摘要：

  A series of new pyrimidine derivatives, including those containing an azole or azine heterocycle linked through a sulfur atom or a thiomethylene group, was synthesized based on 2-amino-6-methylpyrimidine-4(3H)-thione. The synthesized compounds exhibited a pronounced stimulating effect on plants growth in the range of 43-96% compared to heteroauxin.

  DOI：

  10.1134/s1070363220020073
• 作为产物：
  描述：

  2-氨基-4-氯-6-甲基嘧啶 在 盐酸 、 sodium carbonate 、 sodium hydroxide 作用下， 以 水 、 丙酮 为溶剂， 生成 methyl 2-[(2-amino-6-methylpyrimidin-4-yl)thio]acetate
  参考文献：
  名称：

  Synthesis and Plant Growth Stimulating Action of 2-Amino-6-methylpyrimidine-4(3H)-thione Derivatives

  摘要：

  A series of new pyrimidine derivatives, including those containing an azole or azine heterocycle linked through a sulfur atom or a thiomethylene group, was synthesized based on 2-amino-6-methylpyrimidine-4(3H)-thione. The synthesized compounds exhibited a pronounced stimulating effect on plants growth in the range of 43-96% compared to heteroauxin.

  DOI：

  10.1134/s1070363220020073