1-Ethyl-3-[(3-methoxyphenyl)methyl]thiourea

• 分子结构分类: 有机化合物 - 苯类化合物 - 苯酚醚
• 英文名称: 1-Ethyl-3-[(3-methoxyphenyl)methyl]thiourea
• 化学式: C₁₁H₁₆N₂OS
• 分子量: 224.32
• InChiKey: IYGKARNOQFYEMM-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  1.8
• 重原子数：
  15
• 可旋转键数：
  4
• 环数：
  1.0
• sp3杂化的碳原子比例：
  0.363
• 拓扑面积：
  65.4
• 氢给体数：
  2
• 氢受体数：
  2

文献信息

• 3-methoxybenzyl thiourea derivatives and improved lipid compositions containing same
  申请人：The Fanning Corporation

  公开号：US20020147365A1

  公开（公告）日：2002-10-10

  1-(3-methoxybenzyl)-3-substituted thiourea antioxidant compounds and improved lipids compositions which are supplemented with amounts of such antioxidant compounds effective for augmenting oxidative stability of the base lipid are provided. Also provided are methods for enhancing the oxidative stability of a lipid comprising supplementing a base lipid in need of enhanced oxidative stability with at least one 1-(3-methoxybenzyl)-3-substituted thiourea compound of the present invention.

  提供了一种抗氧化化合物，其为1-(3-甲氧基苄基)-3-取代硫脲，以及通过添加这些抗氧化化合物的有效量来改善脂质组成，从而增强基础脂质的氧化稳定性的方法。还提供了一种增强脂质氧化稳定性的方法，该方法包括向需要增强氧化稳定性的基础脂质中补充至少一种本发明所述的1-(3-甲氧基苄基)-3-取代硫脲化合物。
• 3-Methoxybenzyl thiourea derivatives and improved lipid compositions containing same
  申请人：The Fanning Corporation

  公开号：US20010056205A1

  公开（公告）日：2001-12-27

  1-(3-methoxybenzyl)-3-substituted thiourea antioxidant compounds and improved lipids compositions which are supplemented with amounts of such antioxidant compounds effective for augmenting oxidative stability of the base lipid are provided. Also provided are methods for enhancing the oxidative stability of a lipid comprising supplementing a base lipid in need of enhanced oxidative stability with at least one 1-(3-methoxybenzyl)-3-substituted thiourea compound of the present invention.

  本发明提供了一种1-(3-甲氧基苯基)-3-取代硫脲抗氧化化合物以及含有这种抗氧化化合物的改良脂质组成物，其中这种抗氧化化合物的添加量有效增强了基础脂质的氧化稳定性。同时，本发明还提供了增强脂质氧化稳定性的方法，包括将需要增强氧化稳定性的基础脂质补充至少一种本发明的1-(3-甲氧基苯基)-3-取代硫脲化合物。
• Methods and compositions for inhibiting free radical polymerization in skin and hair
  申请人：Fan Tech Ltd.

  公开号：EP1155677A2

  公开（公告）日：2001-11-21

  A method is provided for inhibiting free radical degradation in the skin of a human or nonhuman animal comprising contacting the skin with a skin treatment composition having a concentration of a 1-(3-methoxybenzyl)-3-substituted thiourea compound effective for inhibiting free radical generation. Skin protecting compositions comprising a free radical inhibiting concentration of a 1-(3-methoxybenzyl)-3-substituted thiourea compound, and optionally a sunscreeen composition, are also provided.

  本发明提供了一种抑制人类或非人类动物皮肤自由基降解的方法，该方法包括将皮肤与皮肤处理组合物接触，该组合物具有有效抑制自由基生成的 1-(3-甲氧基苄基)-3-取代的硫脲化合物浓度。本发明还提供了包含抑制自由基浓度的 1-(3-甲氧基苄基)-3-取代的硫脲化合物的皮肤保护组合物，以及可选的防晒组合物。
• Compositions for inhibiting free radical polymerization in skin and hair
  申请人：Fan Tech Ltd.

  公开号：EP1155677B1

  公开（公告）日：2007-06-13
• 3-METHOXYBENZYL THIOUREA DERIVATIVES AND IMPROVED LIPID COMPOSITIONS CONTAINING SAME
  申请人：Abbott, Thomas, P.

  公开号：EP1280495A2

  公开（公告）日：2003-02-05