申请人:Marion Laboratories, Inc.
公开号:US04232014A1
公开(公告)日:1980-11-04
Aminoalkylindans of the formula ##STR1## wherein A represents an alkylene group having 2 to 5 carbons in a straight chain, R.sub.1 represents a lower alkyl having 1 to 3 carbons or is a lower alkoxy having 1 to 3 carbons, B represents --CH.sub.2 -- or ##STR2## and R.sub.2 represents phenyl or phenyl-lower alkyl and the phenyl group in such substituents is unsubstituted or is substituted with 1 to 3 lower alkoxy groups, and acid addition salts of the amines. The compounds have hypotensive activity.
公式为##STR1##的氨基烷基茚,其中A代表直链具有2至5个碳的烷基基团,R.sub.1代表具有1至3个碳的低烷基或是具有1至3个碳的低烷氧基,B代表--CH.sub.2--或##STR2##,R.sub.2代表苯基或苯基-低烷基,这些取代基中的苯基未取代或取代有1至3个低烷氧基,以及这些胺类的酸盐。这些化合物具有降压活性。