十四烷酸庚酯 | 42232-00-8

• 分子结构分类: 有机化合物 - 脂质和类脂质分子 - 脂肪酰基
• 中文名称: 十四烷酸庚酯
• 英文名称: myristic acid heptyl ester
• 英文别名: Myristinsaeure-heptylester；heptyl myristate；n-Tetradecansaeure-n-heptylester；Heptyl tetradecanoate
• CAS: 42232-00-8
• 化学式: C₂₁H₄₂O₂
• 分子量: 326.563
• InChiKey: MFCQPVRHCQCFBB-UHFFFAOYSA-N

物化性质

• 沸点：
  243-245 °C
• 密度：
  0.862±0.06 g/cm3(Predicted)

计算性质

• 辛醇/水分配系数(LogP)：
  9.2
• 重原子数：
  23
• 可旋转键数：
  19
• 环数：
  0.0
• sp3杂化的碳原子比例：
  0.95
• 拓扑面积：
  26.3
• 氢给体数：
  0
• 氢受体数：
  2

反应信息

• 作为产物：
  描述：

  正庚醇 、 肉豆蔻酸 在 silphos 作用下， 反应 0.08h， 以90%的产率得到十四烷酸庚酯
  参考文献：
  名称：

  在作为多相膦试剂的 Silphos [PCl3-n(SiO2)n] 存在下羧酸和醇的无溶剂酯化

  摘要：

  摘要 报道了一种使用多相膦试剂 silphos [PCl3-n(SiO2)n] 从各种芳香族和脂肪酸与伯醇、仲醇和叔醇制备酯的有效无溶剂方法，收率良好。图形概要

  DOI：

  10.1080/00397911.2011.555903

文献信息

• Allantoin-containing preparations for administration as gels and aerosols
  申请人：Alwyn Company, Inc.

  公开号：US20030147968A1

  公开（公告）日：2003-08-07

  Allantoin-containing preparations are prepared in a form suitable for administration as gels and aerosols. In one embodiment of the aerosol formulation, an allantoin-containing composition comprises: (1) water; (2) allantoin in a therapeutically effective quantity; (3) an anionic ethoxylated surfactant; (4) lanolin oil; and (5) cod liver oil. The composition has a viscosity and surface tension in a range that allows the composition to be administered to the skin of a user as an aerosol by a mechanical spray pump. In another aspect of this invention, the allantoin-containing preparations are prepared in a form suitable for administration as gels. The compositions can be substantially anhydrous or can contain water. In one embodiment of the gel formation, an allantoin-containing composition comprises: (1) allantoin in a therapeutically effective quantity; (2) a complex comprising mineral oil and at least one hydrogenated alkylene copolymer; (3) lanolin oil; and (4) cod liver oil. The compositions can comprise other ingredients. Compositions according to the present invention are suitable for the treatment of a number of skin conditions or diseases characterized by ulceration, inflammation, or blistering of the skin, such as epidermolysis bullosa.

  含有尿囊素的制剂以适合作为凝胶和气雾剂的形式制备。在气雾剂配方的一个实施例中，含有尿囊素的组合物包括：（1）水；（2）疗效有效量的尿囊素；（3）阴离子乙氧基化表面活性剂；（4）羊毛脂油；和（5）鱼肝油。该组合物具有粘度和表面张力范围，使得通过机械喷雾泵将组合物作为气雾施用到用户皮肤上。在这项发明的另一个方面，含有尿囊素的制剂以适合作为凝胶的形式制备。这些组合物可以是几乎无水的，也可以含水。在凝胶形成的一个实施例中，含有尿囊素的组合物包括：（1）疗效有效量的尿囊素；（2）包括矿物油和至少一种氢化烷烯共聚物的复合物；（3）羊毛脂油；和（4）鱼肝油。这些组合物可以包含其他成分。根据本发明的组合物适用于治疗一系列皮肤状况或疾病，其特征是皮肤溃疡、炎症或水疱，如表皮溶解性水疱症。
• A method for improving the release of a cast concrete item from the mould by applying to the mould a mould release composition
  申请人：CASTROL A/S

  公开号：EP0328158A1

  公开（公告）日：1989-08-16

  The release of a moulded concrete body from the mould can be improved by applying to the mould an effective amount of a concrete release composition comprising one or more oily esters of aliphatic carboxylic acids with mono- or dihydric alcohols, with a melting point of at the most 35°C, the total number of carbon atoms in the esters being 8-46, in an amount of 26-100% by weight, calculated on the total composition, optionally in admixture with other additives such as mineral oils, vegetable oils, glycols, glycol ethers, alkanols, emulsifiers and/or water.

  在模具上涂抹有效量的混凝土脱模组合物，可改善模制混凝土体的脱模效果，该组合物由一种或多种脂肪族羧酸与一元醇或二元醇的油性酯组成，熔点不超过 35°C、酯中的碳原子总数为 8-46，重量百分比为 26-100%，以总成分计算，可与其他添加剂如矿物油、植物油、乙二醇、乙二醇醚、烷醇、乳化剂和/或水混合使用。
• Temperature-sensitive color-memorizing microcapsulated pigment
  申请人：THE PILOT INK CO., LTD.

  公开号：EP0708153A1

  公开（公告）日：1996-04-24

  A microcapsulated pigment contains, as reaction media one or more specific aliphatic acid alcohol esters obtained from monohydric aliphatic alcohols having odd numbers of carbon atoms and aliphatic carboxylic acids, these reaction media in a homogenious compatible state with chromatic components are occluded in microcapsules to obtain characteristics of thermochromism with a hysteresis range (segment HG) from 8°C to 30°C.

  微胶囊颜料含有一种或多种特定的脂肪族酸醇酯作为反应介质，这些反应介质是从具有奇数碳原子数的一元脂肪族醇和脂肪族羧酸中获得的，这些反应介质在与色素成分均匀相容的状态下被包裹在微胶囊中，从而获得热致变色的特性，其滞后范围（HG 段）为 8°C 至 30°C。
• Thermochromic microencapsulated pigments
  申请人：THE PILOT INK CO., LTD.

  公开号：EP1084860A2

  公开（公告）日：2001-03-21

  Disclosed is a thermochromic microencapsulated pigment which comprises as four essential components (a) an electron-donating chromatic organic compound, (b) an electron-accepting compound, (c) a reaction medium determining the temperatures at which the color reactions of component (a) with component (b) take place, and (d) a color change temperature regulator, the color change temperature regulator (d) comprising one or more compounds selected from the group consisting of esters, alcohols, ketones, acid amides, hydrocarbons, and fatty acids and having a melting point Y (°C) satisfying the relationship (X+30)°C≤Y≤200°C, wherein X (°C) is the melting point of component (c), and the four essential components being microencapsulated.

  本发明公开了一种热致变色微胶囊颜料，它由四种基本成分组成：(a) 一种电子供色有机化合物；(b) 一种电子受色化合物；(c) 一种决定成分(a)与成分(b)发生颜色反应的温度的反应介质；(d) 一种变色温度调节剂、变色温度调节剂(d)包括一种或多种从酯、醇、酮、酸酰胺、烃和脂肪酸组成的组中选出的化合物，其熔点 Y(℃)满足(X+30)℃≤Y≤200℃的关系，其中 X(℃)是组分(c)的熔点，四种基本组分被微胶囊化。
• Thermally color-developing reversibly thermochromic pigment
  申请人：THE PILOT INK CO., LTD.

  公开号：EP1323540A2

  公开（公告）日：2003-07-02

  A thermally color-developing reversibly thermochromic pigment which shows a uniform color density in the coloring temperature range and also shows an optional ΔH value within a range of from 3 to 40°C of the ΔH value (hysteresis temperature range) in a temperature-color density curve. Thermally color-developing reversibly thermochromic pigments of a three component system having a ΔH value of within a range of from 7 to 40°C in which at least essential three components including (a) an electron-donating chromic organic compound, (b) a specified compound selected from gallic acid esters and (c) a reaction medium selected from alcohols, esters, ketones and hydrocarbons, which reversibly generates color reactions of both of the compounds within a specified temperature range and has a melting point of less than 50°C, are microencapsulated, and of a four component system having a ΔH value of within a range of from 3 to 25°C in which a compound (d) selected from monomer compounds having a melting point of 50°C or more or polymer compounds having a softening point of 70°C or more is added to the three component system.

  一种热显色可逆热致变色颜料，在着色温度范围内显示出均匀的色密度，同时在温度-色密度曲线上显示出ΔH 值在ΔH 值的 3 至 40°C 范围内（滞后温度范围）的可选ΔH 值。热显色可逆热致变色颜料的三组分体系，其 ΔH 值在 7 至 40°C 范围内，其中至少必不可少的三组分包括：(a) 电子负载铬有机化合物；(b) 选自没食子酸酯的特定化合物；(c) 选自醇、酯、酮和烃的反应介质、(c)选自醇、酯、酮和碳氢化合物的反应介质；(d)选自熔点为 50℃或以上的单体化合物或软化点为 70℃或以上的聚合物化合物的化合物；(e)选自熔点为 50℃或以上的单体化合物或软化点为 70℃或以上的聚合物化合物的反应介质。