半胱氨酰高半胱氨酸混合物二硫醚 | 4985-47-1

• 分子结构分类: 有机化合物 - 有机酸及其衍生物 - 羧酸及其衍生物
• 中文名称: 半胱氨酰高半胱氨酸混合物二硫醚
• 英文名称: 2-Amino-4-[(2-amino-2-carboxyethyl)disulfanyl]butanoic acid
• CAS: 4985-47-1
• 化学式: C₇H₁₄N₂O₄S₂
• 分子量: 254.3
• InChiKey: YPWSLBHSMIKTPR-UHFFFAOYSA-N

物化性质

• 沸点：
  488.0±45.0 °C(Predicted)
• 密度：
  1.501±0.06 g/cm3(Predicted)

计算性质

• 辛醇/水分配系数(LogP)：
  -5.9
• 重原子数：
  15
• 可旋转键数：
  8
• 环数：
  0.0
• sp3杂化的碳原子比例：
  0.71
• 拓扑面积：
  177
• 氢给体数：
  4
• 氢受体数：
  8

文献信息

• METHODS FOR DETERMINATION OF TOTAL HOMOCYSTEINE
  申请人：Castle Medical, LLC

  公开号：US20160195510A1

  公开（公告）日：2016-07-07

  Disclosed herein are simple, rapid and cost effective methods for determination of endogenous sulfhydryl amino acid species from a sample, example a sample in clinical practice. The method can include mixing of a biological sample with an internal standards which does not require pretreatment or derivatization and/or isotopic dilution. The method can further include analyzing the sample using liquid chromatography tandem mass spectrometer (LC-MS/MS) to determine the concentration of sulfhydryl amino acid species.
• BIOMARKERS AND METHODS OF PREDICTION
  申请人：Hoffmann-La Roche Inc.

  公开号：US20170322225A1

  公开（公告）日：2017-11-09

  Subject of the present invention are biomarkers and methods for the identification of risk for subsequent cardiovascular event (e.g. coronary heart disease death, non-fatal myocardial infarction, ischemic stroke, hospitalizations for unstable angina pectotis, cardiac arrest) in patients that have experienced an acute coronary syndrome, comprising the detecting the level of NT-proBNP, homocysteine and CRP.